Timeline

Iñaki Guijarro

Head of Facility

07 Feb 2023

publication

Solid-state NMR molecular snapshots of Aspergillus fumigatus cell wall architecture during a conidial morphotype transition.

24 Jan 2023

publication

Conidium Specific Polysaccharides in Aspergillus fumigatus.

22 Dec 2022

publication

Design of crotoxin-based peptides with potentiator activity targeting the ΔF508NBD1 Cystic Fibrosis Transmembrane Conductance Regulator.

09 Aug 2022

publication

Dynamics and structural changes of calmodulin upon interaction with the antagonist calmidazolium.

01 Jun 2022

publication

Identification of Chemical Probes Targeting MBD2.

01 Dec 2019

publication

Assembly and disassembly of Aspergillus fumigatus conidial rodlets

19 Nov 2019

event

Thesis defense: Borja Rodriguez de Francisco – “Self-assembly into functional amyloids of Aspergillus fumigatus hydrophobins”

18 Jun 2019

publication

Cn29, a novel orphan peptide found in the venom of the scorpion Centruroides noxius: Structure and function

01 May 2019

publication

The puzzling construction of the conidial outer layer of Aspergillus fumigatus.

07 Aug 2018

publication

Probing Structural Changes during Self-assembly of Surface-Active Hydrophobin Proteins that Form Functional Amyloids in Fungi.

24 Jul 2018

project

Hydrophobin: functional amyloids from the fungal pathogen Aspergillus fumigatus

28 Jun 2018

team

Biological NMR and HDX-MS Technological Platform

29 May 2018

event

Half-Day Symposium “NMR Beyond Protein Structures”

12 Jan 2018

publication

Calcium-dependent disorder-to-order transitions are central to the secretion and folding of the CyaA toxin of Bordetella pertussis, the causative agent of whooping cough.

24 Dec 2017

publication

Role of Hydrophobins in Aspergillus fumigatus

27 Jan 2017

event

HDX-MS/NMR DAY

20 Nov 2015

project

Biophysical characterization of the translocation process of Bordetella pertussis adenylate cyclase toxin CyaA

09 Sep 2015

tool

Nuclear Magnetic Resonance spectrometers

07 Jul 2015

project

Functional amyloids of the cell wall of the fungal pathogen Aspergillus fumigatus

11 May 2015

team

Structural Bioinformatics

01 Apr 2015

publication

(1)H, (13)C and (15)N resonance assignments of the RodA hydrophobin from the opportunistic pathogen Aspergillus fumigatus

22 Feb 2013

publication

New insights for native production of MSP1(19), the disulfide-rich C-terminal fragment from Plasmodium falciparum merozoite surface protein 1

09 Jan 2013

publication

Solution structure of an archaeal DNA binding protein with an eukaryotic zinc finger fold

31 May 2012

publication

Hydrophobins–unique fungal proteins

22 Jan 2010

publication

Characterization of the regions involved in the calcium-induced folding of the intrinsically disordered RTX motifs from the bordetella pertussis adenylate cyclase toxin

19 Jan 2010

publication

Calmodulin-induced conformational and hydrodynamic changes in the catalytic domain of Bordetella pertussis adenylate cyclase toxin

17 Nov 2008

publication

RTX calcium binding motifs are intrinsically disordered in the absence of calcium: implication for protein secretion

14 Sep 2006

publication

A novel archaeal regulatory protein, Sta1, activates transcription from viral promoters

01 Jan 2006

publication

Diversity and junction residues as hotspots of binding energy in an antibody neutralizing the dengue virus

01 Jun 2005

publication

A new type of scorpion Na+-channel-toxin-like polypeptide active on K+ channels

18 Nov 2003

publication

Assistance of maltose binding protein to the in vivo folding of the disulfide-rich C-terminal fragment from Plasmodium falciparum merozoite surface protein 1 expressed in Escherichia coli

01 Sep 2003

publication

Solution structure of Pi4, a short four-disulfide-bridged scorpion toxin specific of potassium channels

01 Sep 2003

publication

Synthesis and characterization of Pi4, a scorpion toxin from Pandinus imperator that acts on K+ channels

01 Mar 2002

publication

Structure and dynamics of the anticodon arm binding domain of Bacillus stearothermophilus Tyrosyl-tRNA synthetase

22 Aug 2001

publication

Preparation and characterization of purified amyloid fibrils

10 Aug 2001

publication

Dependence on solution conditions of aggregation and amyloid formation by an SH3 domain

01 Jan 2000

publication

Evidence concerning rate-limiting steps in protein folding from the effects of trifluoroethanol

15 Feb 1999

publication

Cryo-electron microscopy structure of an SH3 amyloid fibril and model of the molecular packing

14 Apr 1998

publication

Amyloid fibril formation by an SH3 domain

27 Feb 1998

publication

Folding kinetics of the SH3 domain of PI3 kinase by real-time NMR combined with optical spectroscopy

24 Feb 1998

publication

The folding kinetics and thermodynamics of the Fyn-SH3 domain

01 Feb 1998

publication

Does a peptide bound to a monoclonal antibody always adopt a unique conformation?

01 Jul 1997

publication

The “pre-molten globule,” a new intermediate in protein folding

01 Oct 1995

publication

Chemical structure and translation inhibition studies of the antibiotic microcin C7

07 Mar 1995

publication

A little guide for advanced search:

Solid-state NMR molecular snapshots of Aspergillus fumigatus cell wall architecture during a conidial morphotype transition.

Conidium Specific Polysaccharides in Aspergillus fumigatus.

Design of crotoxin-based peptides with potentiator activity targeting the ΔF508NBD1 Cystic Fibrosis Transmembrane Conductance Regulator.

Dynamics and structural changes of calmodulin upon interaction with the antagonist calmidazolium.

Identification of Chemical Probes Targeting MBD2.

Assembly and disassembly of Aspergillus fumigatus conidial rodlets

Thesis defense: Borja Rodriguez de Francisco – “Self-assembly into functional amyloids of Aspergillus fumigatus hydrophobins”

Cn29, a novel orphan peptide found in the venom of the scorpion Centruroides noxius: Structure and function

The puzzling construction of the conidial outer layer of Aspergillus fumigatus.

Probing Structural Changes during Self-assembly of Surface-Active Hydrophobin Proteins that Form Functional Amyloids in Fungi.

Hydrophobin: functional amyloids from the fungal pathogen Aspergillus fumigatus

Biological NMR and HDX-MS Technological Platform

Half-Day Symposium “NMR Beyond Protein Structures”

Calcium-dependent disorder-to-order transitions are central to the secretion and folding of the CyaA toxin of Bordetella pertussis, the causative agent of whooping cough.

Role of Hydrophobins in Aspergillus fumigatus

HDX-MS/NMR DAY

Biophysical characterization of the translocation process of Bordetella pertussis adenylate cyclase toxin CyaA

Nuclear Magnetic Resonance spectrometers

Functional amyloids of the cell wall of the fungal pathogen Aspergillus fumigatus

Structural Bioinformatics

(1)H, (13)C and (15)N resonance assignments of the RodA hydrophobin from the opportunistic pathogen Aspergillus fumigatus

New insights for native production of MSP1(19), the disulfide-rich C-terminal fragment from Plasmodium falciparum merozoite surface protein 1

Solution structure of an archaeal DNA binding protein with an eukaryotic zinc finger fold

Hydrophobins–unique fungal proteins

Characterization of the regions involved in the calcium-induced folding of the intrinsically disordered RTX motifs from the bordetella pertussis adenylate cyclase toxin

Calmodulin-induced conformational and hydrodynamic changes in the catalytic domain of Bordetella pertussis adenylate cyclase toxin

RTX calcium binding motifs are intrinsically disordered in the absence of calcium: implication for protein secretion

A novel archaeal regulatory protein, Sta1, activates transcription from viral promoters

Diversity and junction residues as hotspots of binding energy in an antibody neutralizing the dengue virus

A new type of scorpion Na+-channel-toxin-like polypeptide active on K+ channels

Assistance of maltose binding protein to the in vivo folding of the disulfide-rich C-terminal fragment from Plasmodium falciparum merozoite surface protein 1 expressed in Escherichia coli

Solution structure of Pi4, a short four-disulfide-bridged scorpion toxin specific of potassium channels

Synthesis and characterization of Pi4, a scorpion toxin from Pandinus imperator that acts on K+ channels

Structure and dynamics of the anticodon arm binding domain of Bacillus stearothermophilus Tyrosyl-tRNA synthetase

Preparation and characterization of purified amyloid fibrils

Dependence on solution conditions of aggregation and amyloid formation by an SH3 domain

Evidence concerning rate-limiting steps in protein folding from the effects of trifluoroethanol

Cryo-electron microscopy structure of an SH3 amyloid fibril and model of the molecular packing

Amyloid fibril formation by an SH3 domain

Folding kinetics of the SH3 domain of PI3 kinase by real-time NMR combined with optical spectroscopy

The folding kinetics and thermodynamics of the Fyn-SH3 domain

Does a peptide bound to a monoclonal antibody always adopt a unique conformation?

The “pre-molten globule,” a new intermediate in protein folding

Chemical structure and translation inhibition studies of the antibiotic microcin C7

Protein folding intermediates with rapidly exchangeable amide protons contain authentic hydrogen-bonded secondary structures