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© Pierre Lafaye
Astrocytes marqués par des anticorps VHH anti-GFAP. Des anticorps d'alpagas dirigés contre une protéine spécifique des astrocytes, la GFAP (Glial Fibrillary Acidic Protein), ont été obtenus à partir de camélidés immunisés. La partie VHH (partie de l'anticorps qui reconnaît l'antigène) a été exprimée sous forme recombinante chez Escherichia coli.
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About

Gaelle Chauveau-Le Friec is a research technician (Bachelor Degree in Biology, Faculté Paris XI Orsay, 1996) specialized in embryo microinjection. Her experience in embryo microinjection started during her professional experience in the Society Bioprotein (1998-2000) where she learnt and realised her first transgenesis techniques in mice and rabbit models. She pursued her experience as microinjectionnist in the society Genoway (2000-2006), where she continued the microinjection of one-cell mouse embryos for obtaining transgenic mice by classical transgenesis and of mouse blastocysts with Embryonic Stem cells in order to get germ-line chimeras. She started also there the microinjection of rat embryos together with cloning techniques using this animal model.

Since 2007 she has been research technician specialized in microinjection in the Mouse Genetics Engineering Center at the Institut Pasteur where she has been improving her experience with all type of transgene microinjection (BACs, lentivirus, nucleases) in mouse and rat embryos .

She holds the degrees “Certification d’Experimentation Animale Niveau II” (Lyon, 2005) and “Initiation a la Chirurgie experimentale” (Lyon, 2014).

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