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© Research
National Reference Center

Corynebacteria of the diphtheriae complex

Department of Global Health

Sylvain Brisse

Director

Edgar Badell-Ocando

Deputy Director

Julie Toubiana

Deputy Director
Biodiversity and Epidemiology of Bacterial Pathogens
Department of Global Health

About

The French National Reference Center for diphtheria (officially: the NRC for Corynebacteria of the diphtheriae complex; web pages in French) operates under the mandate of Public Health France (Santé publique France). Its missions are to diagnose and characterize potentially toxigenic strains of Corynebacterium diphtheriae, Corynebacterium ulcerans and related species. In case of detection of the diphtheria toxin gene, we alert public health authorities, who take action to avoid transmission and outbreaks. We also provide advice to medical microbiology laboratories and clinicians in the human and veterinary sectors (companion animals are often infected by C. ulcerans).

More information dedicated to French medical or veterinary microbiologists and clinicians is available on the official NRC website (see above link). 

 

 

 

Projects

Project
Ongoing
3 Members

The GenEpi-BioTrain programme: Interdisciplinary training in genomic epidemiology and public health bioinformatics

Sylvain Brisse (PI)

This interdisciplinary program, funded by the ECDC, integrates both lectures and hands-on practical sessions provided by various host institutions to enhance surveillance, preparedness, and the ability to respond to outbreaks. Institutes included in the […]
Project
Ongoing
34 Members

Welcome to the Nanopore User Group at Institut Pasteur webpage

Chiara Crestani (PI)

About the Nanopore User Group: The Nanopore User Group at Institut Pasteur was established in 2019 with the primary goal of fostering collaboration, sharing knowledge, and advancing the application of Oxford Nanopore Technologies (ONT) […]
Project
Ongoing
6 Members

Diphtheria and Corynebacteria: genomics, evolution and epidemiology

Sylvain Brisse (PI)

Our research on Corynebacterium diphtheriae and related bacterial pathogenic species, including Corynebacterium ulcerans,  aims at defining the diversity, evolution and epidemiology of the agents of diphtheria and related infections. We study human and animal clinical […]
Project
Ongoing
15 Members

Genomic taxonomy of bacterial strains: universal nomenclatures for epidemiology and population biology

Sylvain Brisse (PI)

High-throughput sequencing has revolutionized our abilities to track and characterize novel bacterial strains as they emerge and disseminate globally. Genome-based epidemiological typing systems provide ultimate resolution for strain discrimination. Genome sequences may also be […]
Project
Ongoing
3 Members

Bioinformatics of genome sequencing applied to epidemiological surveillance of infectious agents

Sylvain Brisse (PI)

The Institut Pasteur has voluminous activities of microbial strain characterisation, in the context of epidemiological surveillance, biological resource centres collections management, and research. These activities involve National Reference Centers, WHO-collaborative centers, biological resources centers […]

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