Timeline

Margaret Buckingham

Honorary President of the Departement

06 May 2024

publication

Cardiac progenitor cells of the first and second Heart Fields. Congenital Heart Diseases: The Broken Heart

29 Mar 2024

publication

Messenger RNA in differentiating muscle cells-my experience in François Gros’ lab in the 1970s and 80s.

01 Jan 2021

publication

M-Cadherin Is a PAX3 Target During Myotome Patterning.

24 Oct 2020

publication

In remembrance of David Yaffe.

18 May 2020

publication

Commentary on Distinct, but Previously Confused, Nrf1 Transcription Factors and Their Functions in Redox Regulation.

06 Jun 2019

publication

PAX3 Confers Functional Heterogeneity in Skeletal Muscle Stem Cell Responses to Environmental Stress.

01 Nov 2018

publication

The deployment of cell lineages that form the mammalian heart.

14 Aug 2018

publication

The role of Pitx2 and Pitx3 in muscle stem cells gives new insights into P38α MAP kinase and redox regulation of muscle regeneration

06 Jun 2017

publication

Gene regulatory networks and cell lineages that underlie the formation of skeletal muscle

01 Mar 2016

publication

Endothelial cell specification in the somite is compromised in Pax3-positive progenitors of Foxc1/2 conditional mutants, with loss of forelimb myogenesis.

18 Feb 2016

publication

Progressive developmental restriction, acquisition of left-right identity and cell growth behavior during lobe formation in mouse liver development

01 Jan 2016

publication

Tissue Differentiation: A Personal Account of Research on Myogenesis and Cardiogenesis.

01 Jan 2016

publication

First and second heart fields.

04 Nov 2015

publication

Fine-tuning the onset of myogenesis by homeobox proteins that interact with the Myf5 limb enhancer

28 Sep 2015

publication

PAX3 and PAX7 as upstream regulators of myogenesis

03 Feb 2015

publication

Clonal analysis reveals a common origin between nonsomite-derived neck muscles and heart myocardium.

02 Feb 2015

publication

Cardiac cell lineages that form the heart

01 Oct 2014

publication

Heart fields and cardiac morphogenesis

10 Aug 2014

publication

Interactions with John Gurdon–muscle as a mesodermal read-out and the community effect

03 Jun 2014

publication

Notch regulation of myogenic versus endothelial fates of cells that migrate from the somite to the limb

27 May 2014

publication

Redox regulation by Pitx2 and Pitx3 is critical for fetal myogenesis

12 May 2014

publication

Prdm1 functions in the mesoderm of the second heart field, where it interacts genetically with Tbx1, during outflow tract morphogenesis in the mouse embryo

10 Feb 2014

publication

Gene regulatory networks and transcriptional mechanisms that control myogenesis.

12 Jul 2013

publication

Lying low but ready for action: the quiescent muscle satellite cell

01 Jun 2013

publication

Resolving cell lineage contributions to the ventricular conduction system with a Cx40-GFP allele: a dual contribution of the first and second heart fields.

01 May 2013

publication

Itm2a is a Pax3 target gene, expressed at sites of skeletal muscle formation in vivo

25 Apr 2013

publication

Six homeoproteins directly activate Myod expression in the gene regulatory networks that control early myogenesis

04 Feb 2013

publication

Direct molecular regulation of the myogenic determination gene Myf5 by Pax3, with modulation by Six1/4 factors, is exemplified by the -111 kb-Myf5 enhancer

15 Jan 2013

publication

Quantitative analysis of polarity in 3D reveals local cell coordination in the embryonic mouse heart

23 Oct 2012

publication

Fibroblast growth factor 10 gene regulation in the second heart field by Tbx1, Nkx2-5, and Islet1 reveals a genetic switch for down-regulation in the myocardium

15 Sep 2012

publication

Sonic hedgehog acts cell-autonomously on muscle precursor cells to generate limb muscle diversity

05 Sep 2012

publication

Asymmetric fate of the posterior part of the second heart field results in unexpected left/right contributions to both poles of the heart

01 Aug 2012

publication

Lineage tree for the venous pole of the heart: clonal analysis clarifies controversial genealogy based on genetic tracing

12 Jul 2012

publication

Pax3( GFP ) , a new reporter for the melanocyte lineage, highlights novel aspects of PAX3 expression in the skin

01 Jul 2012

publication

Muscle satellite cells are primed for myogenesis but maintain quiescence with sequestration of Myf5 mRNA targeted by microRNA-31 in mRNP granules

20 Apr 2012

publication

Non conservation of function for the evolutionarily conserved prdm1 protein in the control of the slow twitch myogenic program in the mouse embryo

16 Mar 2012

publication

Studying the choreography of cardiogenesis. Interviewed by Ruth Williams

09 Mar 2012

publication

What does the concept of the stem cell niche really mean today?

08 Dec 2011

publication

Characterization of Pax3-expressing cells from adult blood vessels

13 Sep 2011

publication

Tracing cells for tracking cell lineage and clonal behavior

21 Apr 2011

publication

Lack of in vivo functional compensation between Pax family groups II and III in rodents

08 Dec 2010

publication

Transcriptome analyses based on genetic screens for Pax3 myogenic targets in the mouse embryo.

03 Nov 2010

publication

Megarole for microRNA in muscle disease.

01 Oct 2010

publication

Clonal analysis reveals common lineage relationships between head muscles and second heart field derivatives in the mouse embryo.

01 Aug 2010

publication

Developmental mechanisms, patterning and evolution.

09 Jul 2010

publication

Biphasic development of the mammalian ventricular conduction system.

01 Apr 2010

publication

A Pax3/Dmrt2/Myf5 regulatory cascade functions at the onset of myogenesis.

01 Mar 2010

publication

An adult tissue-specific stem cell in its niche: a gene profiling analysis of in vivo quiescent and activated muscle satellite cells.

19 Feb 2010

publication

Role of mesodermal FGF8 and FGF10 overlaps in the development of the arterial pole of the heart and pharyngeal arch arteries.

01 Feb 2010

publication

The formation of the embryonic mouse heart: heart fields and myocardial cell lineages.

01 Jan 2010

publication

How to make a heart: the origin and regulation of cardiac progenitor cells.

01 Dec 2009

publication

Pax3:Foxc2 reciprocal repression in the somite modulates muscular versus vascular cell fate choice in multipotent progenitors.

15 Nov 2009

publication

microRNAs gain magnitude in muscle.

01 Oct 2009

publication

Distinct and dynamic myogenic populations in the vertebrate embryo

11 Aug 2009

publication

Muscle stem cell behavior is modified by microRNA-27 regulation of Pax3 expression.

05 Jun 2009

publication

Landmarks and lineages in the developing heart.

01 Mar 2009

publication

The regulatory mechanisms that underlie inappropriate transcription of the myogenic determination gene Myf5 in the central nervous system.

01 Feb 2009

publication

Conotruncal defects associated with anomalous pulmonary venous connections.

01 Feb 2009

publication

The extracellular domain of Lrp5/6 inhibits noncanonical Wnt signaling in vivo.

01 Jan 2009

publication

Skeletal muscle differentiation of embryonic mesoangioblasts requires pax3 activity.

01 Nov 2008

publication

An FGF autocrine loop initiated in second heart field mesoderm regulates morphogenesis at the arterial pole of the heart.

01 Aug 2008

publication

Skeletal muscle stem cells.

01 Jul 2008

publication

Pax3 regulation of FGF signaling affects the progression of embryonic progenitor cells into the myogenic program.

01 Mar 2008

publication

Atrial myocardium derives from the posterior region of the second heart field, which acquires left-right identity as Pitx2c is expressed.

01 Jan 2008

publication

Myocardium at the base of the aorta and pulmonary trunk is prefigured in the outflow tract of the heart and in subdomains of the second heart field.

01 Jan 2008

publication

Integration of embryonic and fetal skeletal myogenic programs at the myosin light chain 1f/3f locus.

01 Dec 2007

publication

The A17 enhancer directs expression of Myf5 to muscle satellite cells but Mrf4 to myonuclei.

03 Jul 2007

publication

Six proteins regulate the activation of Myf5 expression in embryonic mouse limbs.

15 Apr 2007

publication

Beta catenin-independent activation of MyoD in presomitic mesoderm requires PKC and depends on Pax3 transcriptional activity.

09 Mar 2007

publication

An Nkx2-5/Bmp2/Smad1 negative feedback loop controls heart progenitor specification and proliferation.

01 Jan 2007

publication

The role of Pax genes in the development of tissues and organs: Pax3 and Pax7 regulate muscle progenitor cell functions.

01 Jan 2007

publication

Skeletal muscle progenitor cells and the role of Pax genes.

01 Dec 2006

publication

Myogenic progenitor cells in the mouse embryo are marked by the expression of Pax3/7 genes that regulate their survival and myogenic potential.

01 Oct 2006

publication

Myogenic progenitor cells and skeletal myogenesis in vertebrates.

01 Sep 2006

publication

A novel genetic hierarchy functions during hypaxial myogenesis: Pax3 directly activates Myf5 in muscle progenitor cells in the limb.

01 Sep 2006

publication

The Wnt/beta-catenin pathway regulates Gli-mediated Myf5 expression during somitogenesis.

01 Jul 2006

publication

Congenital heart defects in Fgfr2-IIIb and Fgf10 mutant mice.

15 Jun 2006

publication

Left and right ventricular contributions to the formation of the interventricular septum in the mouse heart.

01 May 2006

publication

Integrin alpha6beta1-laminin interactions regulate early myotome formation in the mouse embryo.

17 Feb 2006

publication

Rotation of the myocardial wall of the outflow tract is implicated in the normal positioning of the great arteries.

01 Feb 2006

publication

Smooth muscle of the dorsal aorta shares a common clonal origin with skeletal muscle of the myotome.

02 Jan 2006

publication

Pax3 and Pax7 have distinct and overlapping functions in adult muscle progenitor cells.

01 Nov 2005

publication

Building the mammalian heart from two sources of myocardial cells.

01 Sep 2005

publication

Direct isolation of satellite cells for skeletal muscle regeneration

16 Jun 2005

publication

A Pax3/Pax7-dependent population of skeletal muscle progenitor cells.

31 Dec 2004

publication

Characterization of a cardiac-specific enhancer, which directs {alpha}-cardiac actin gene transcription in the mouse adult heart.

23 Sep 2004

publication

Mrf4 determines skeletal muscle identity in Myf5:Myod double-mutant mice.

06 Aug 2004

publication

Right ventricular myocardium derives from the anterior heart field.

26 May 2004

publication

The in vivo form of the murine class VI POU protein Emb is larger than that encoded by previously described transcripts.

15 May 2004

publication

An enhancer directs differential expression of the linked Mrf4 and Myf5 myogenic regulatory genes in the mouse.

01 May 2004

publication

Divergent functions of murine Pax3 and Pax7 in limb muscle development.

01 May 2004

publication

The clonal origin of myocardial cells in different regions of the embryonic mouse heart.

01 Apr 2004

publication

A novel complex regulates cardiac actin gene expression through interaction of Emb, a class VI POU domain protein, MEF2D, and the histone transacetylase p300.

05 Jan 2004

publication

Oriented clonal cell growth in the developing mouse myocardium underlies cardiac morphogenesis.

15 Dec 2003

publication

Cell history determines the maintenance of transcriptional differences between left and right ventricular cardiomyocytes in the developing mouse heart.

01 Dec 2003

publication

The transcriptional activator PAX3-FKHR rescues the defects of Pax3 mutant mice but induces a myogenic gain-of-function phenotype with ligand-independent activation of Met signaling in vivo.

01 Aug 2003

publication

Analysis of a key regulatory region upstream of the Myf5 gene reveals multiple phases of myogenesis, orchestrated at each site by a combination of elements dispersed throughout the locus.

01 Aug 2003

publication

A retrospective clonal analysis of the myocardium reveals two phases of clonal growth in the developing mouse heart.

01 Jan 2003

publication

[The mouse as a model for heart morphogenesis in mammals: the origin of myocytes and studies with cardiac explants].

01 Jan 2003

publication

[The mouse as a model of heart morphogenesis in mammals: origin and lineage of myocytes].

01 Jan 2003

publication

How the community effect orchestrates muscle differentiation.

01 Jan 2003

publication

The formation of skeletal muscle: from somite to limb.

15 Nov 2002

publication

Kinetics of myoblast proliferation show that resident satellite cells are competent to fully regenerate skeletal muscle fibers.

01 Oct 2002

publication

The early epaxial enhancer is essential for the initial expression of the skeletal muscle determination gene Myf5 but not for subsequent, multiple phases of somitic myogenesis.

01 Apr 2002

publication

The anterior heart-forming field: voyage to the arterial pole of the heart.

01 Sep 2001

publication

The arterial pole of the mouse heart forms from Fgf10-expressing cells in pharyngeal mesoderm.

01 Aug 2001

publication

Skeletal muscle formation in vertebrates.

01 Jun 2001

publication

MLC3F transgene expression in iv mutant mice reveals the importance of left-right signalling pathways for the acquisition of left and right atrial but not ventricular compartment identity.

01 May 2001

publication

Transplanted primary neonatal myoblasts can give rise to functional satellite cells as identified using the Myf5nlacZl+ mouse.

14 Dec 2000

publication

A cellular cornucopia.

11 Dec 2000

publication

Expression of CD34 and Myf5 defines the majority of quiescent adult skeletal muscle satellite cells.

24 Nov 2000

publication

Multiple transcriptional domains, with distinct left and right components, in the atrial chambers of the developing heart.

01 Oct 2000

publication

Modular long-range regulation of Myf5 reveals unexpected heterogeneity between skeletal muscles in the mouse embryo.

15 Sep 2000

publication

Modular regulation of the MLC1F/3F gene and striated muscle diversity.

01 Jan 2000

publication

The birth of muscle progenitor cells in the mouse: spatiotemporal considerations.

01 Jan 2000

publication

Myf5 is a novel early axonal marker in the mouse brain and is subjected to post-transcriptional regulation in neurons.

01 Jan 2000

publication

Suppression of atrial myosin gene expression occurs independently in the left and right ventricles of the developing mouse heart.

15 Dec 1999

publication

From insect eye to vertebrate muscle: redeployment of a regulatory network.

01 Oct 1999

publication

Transplacental delivery of the Wnt antagonist Frzb1 inhibits development of caudal paraxial mesoderm and skeletal myogenesis in mouse embryos.

01 Sep 1999

publication

In vivo satellite cell activation via Myf5 and MyoD in regenerating mouse skeletal muscle.

01 Sep 1999

publication

Sonic hedgehog controls epaxial muscle determination through Myf5 activation.

01 Jun 1999

publication

The homeobox gene Msx1 is expressed in a subset of somites, and in muscle progenitor cells migrating into the forelimb.

01 Jan 1999

publication

Cardiosensor mice and transcriptional subdomains of the vertebrate heart.

01 Nov 1998

publication

Differential activation of Myf5 and MyoD by different Wnts in explants of mouse paraxial mesoderm and the later activation of myogenesis in the absence of Myf5.

01 Oct 1998

publication

DAN is a secreted glycoprotein related to Xenopus cerberus.

17 Jul 1998

publication

A novel GFPneo vector designed for the isolation and analysis of enhancer elements in transfected mammalian cells.

01 Jul 1998

publication

The formation and maturation of skeletal muscle in the mouse: the myosin MLC1F/3F gene as a molecular model.

01 Jun 1998

publication

Dynamic left/right regionalisation of endogenous myosin light chain 3F transcripts in the developing mouse heart.

01 Aug 1997

publication

Regionalized transcriptional domains of myosin light chain 3f transgenes in the embryonic mouse heart: morphogenetic implications.

15 Jul 1997

publication

Embryonic and fetal myogenic programs act through separate enhancers at the MLC1F/3F locus.

01 Jul 1997

publication

Insertional mutation of the mouse Msx1 homeobox gene by an nlacZ reporter gene.

01 Jun 1997

publication

Fibre type-specific and nerve-dependent regulation of myosin light chain 1 slow promoter in regenerating muscle.

01 May 1997

publication

Manipulating myosin light chain 2 isoforms in vivo: a transgenic approach to understanding contractile protein diversity.

04 Apr 1997

publication

Redefining the genetic hierarchies controlling skeletal myogenesis: Pax-3 and Myf-5 act upstream of MyoD.

01 Jan 1997

publication

[Early stages of myogenesis as seen through the action of the myf-5 gene].

01 Jan 1997

publication

Myogenesis in the mouse embryo.

21 Nov 1996

publication

Muscle progenitor cells failing to respond to positional cues adopt non-myogenic fates in myf-5 null mice.

01 Jul 1996

publication

Gene targeting the myf-5 locus with nlacZ reveals expression of this myogenic factor in mature skeletal muscle fibres as well as early embryonic muscle.

01 Jun 1996

publication

How is myogenesis initiated in the embryo?

01 May 1996

publication

Skeletal muscle development and the role of the myogenic regulatory factors.

01 Feb 1996

publication

Activation of different myogenic pathways: myf-5 is induced by the neural tube and MyoD by the dorsal ectoderm in mouse paraxial mesoderm.

10 Jan 1996

publication

Developmental and tissue-specific regulation of the murine cardiac actin gene in vivo depends on distinct skeletal and cardiac muscle-specific enhancer elements in addition to the proximal promoter.

01 Dec 1995

publication

Lineage restriction of the myogenic conversion factor myf-5 in the brain.

01 Aug 1995

publication

A skeletal muscle-specific enhancer regulated by factors binding to E and CArG boxes is present in the promoter of the mouse myosin light-chain 1A gene.

01 Apr 1995

publication

Muscle-specific gene expression during myogenesis in the mouse.

01 Apr 1995

publication

Myosin light chain 3F regulatory sequences confer regionalized cardiac and skeletal muscle expression in transgenic mice.

14 Mar 1995

publication

Myoblast differentiation during mammalian somitogenesis is dependent upon a community effect.

01 Oct 1994

publication

A population of myogenic cells derived from the mouse neural tube.

01 Oct 1994

publication

Muscle: the regulation of myogenesis.

15 Jul 1994

publication

Molecular biology of muscle development.

01 Jul 1994

publication

Msx1 is close but not allelic to either Hm or Hx on mouse chromosome 5.

01 May 1994

publication

Novel muscle-specific enhancer sequences upstream of the cardiac actin gene.

18 Jan 1994

publication

Mouse limb muscle is determined in the absence of the earliest myogenic factor myf-5.

01 Jan 1994

publication

Muscle differentiation. Which myogenic factors make muscle?

01 Dec 1993

publication

Expression of the dystrophin-related protein (utrophin) gene during mouse embryogenesis.

01 Nov 1993

publication

Type 2X-myosin heavy chain is coded by a muscle fiber type-specific and developmentally regulated gene.

01 Nov 1993

publication

Modulation of contractile protein gene expression in fetal murine crural muscles: emergence of muscle diversity.

01 Sep 1993

publication

Expression of myogenic factors in the mouse: myf-5, the first member of the MyoD gene family to be transcribed during skeletal myogenesis.

01 Apr 1993

publication

Contractile protein gene expression in primary myotubes of embryonic mouse hindlimb muscles.

01 Jan 1993

publication

Re-localization of Actsk-1 to mouse chromosome 8, a new region of homology with human chromosome 1.

01 Jan 1993

publication

[Induction phenomena during vertebrate limb development and homeo box gene expression].

01 Nov 1992

publication

Localization of dystrophin gene transcripts during mouse embryogenesis.

01 Aug 1992

publication

Multiple sites of Hox-7 expression during mouse embryogenesis: comparison with retinoic acid receptor mRNA localization.

01 Jul 1992

publication

Activation of the gene encoding the glycolytic enzyme beta-enolase during early myogenesis precedes an increased expression during fetal muscle development.

01 Jun 1992

publication

Expression of NCAM isoforms during skeletal myogenesis in the mouse embryo.

01 Apr 1992

publication

Making muscle in mammals.

01 Mar 1992

publication

MyoD, myogenin independent differentiation of primordial myoblasts in mouse somites.

01 Jan 1992

publication

Expression of muscle genes in the mouse embryo.

01 Jan 1992

publication

Myogenesis in the mouse.

01 Jan 1992

publication

Actin and myosin genes are transcriptionally regulated during mouse skeletal muscle development.

01 Dec 1991

publication

The apical ectodermal ridge regulates Hox-7 and Hox-8 gene expression in developing chick limb buds.

01 Nov 1991

publication

Developmental regulation of creatine kinase gene expression by myogenic factors in embryonic mouse and chick skeletal muscle.

01 Jun 1991

publication

The muscle regulatory gene, Myf-6, has a biphasic pattern of expression during early mouse development.

01 Apr 1991

publication

Early expression of the myogenic regulatory gene, myf-5, in precursor cells of skeletal muscle in the mouse embryo.

01 Feb 1991

publication

alpha-Actin proteins and gene transcripts are colocalized in embryonic mouse muscle.

01 Jan 1991

publication

Three linked myosin heavy chain genes clustered within 370 kb of each other show independent transcriptional and post-transcriptional regulation during differentiation of a mouse muscle cell line.

01 Jan 1991

publication

Carbonic anhydrase III, an early mesodermal marker, is expressed in embryonic mouse skeletal muscle and notochord.

01 Dec 1990

publication

Developmental regulation of myosin gene expression in mouse cardiac muscle.

01 Oct 1990

publication

The expression of myosin genes in developing skeletal muscle in the mouse embryo.

01 Jun 1990

publication

Transcriptional regulation of actin and myosin genes during differentiation of a mouse muscle cell line.

01 Apr 1990

publication

The human homeobox gene HOX7 maps to chromosome 4p16.1 and may be implicated in Wolf-Hirschhorn syndrome.

20 Feb 1990

publication

Genetic analysis of the interaction between cardiac and skeletal actin gene expression in striated muscle of the mouse.

01 Dec 1989

publication

Myosin light chain gene expression in developing and denervated fetal muscle in the mouse.

28 Sep 1989

publication

Expression of two myogenic regulatory factors myogenin and MyoD1 during mouse embryogenesis.

01 Jul 1989

publication

A developmental study of the abnormal expression of alpha-cardiac and alpha-skeletal actins in the striated muscle of a mutant mouse.

01 Jul 1989

publication

The control of muscle gene expression: a review of molecular studies on the production and processing of primary transcripts.

01 May 1989

publication

Nonsynchronous accumulation of alpha-skeletal actin and beta-myosin heavy chain mRNAs during early stages of pressure-overload–induced cardiac hypertrophy demonstrated by in situ hybridization.

01 Feb 1989

publication

Chromosomal assignment of two myosin alkali light-chain genes encoding the ventricular/slow skeletal muscle isoform and the atrial/fetal muscle isoform (MYL3, MYL4).

15 Jan 1989

publication

Chronic stimulation-induced changes of myosin light chains at the mRNA and protein levels in rat fast-twitch muscle.

01 Jan 1989

publication

Hox-7, a mouse homeobox gene with a novel pattern of expression during embryogenesis.

11 Nov 1988

publication

Promoter analysis of myosin alkali light chain genes expressed in mouse striated muscle.

05 Sep 1988

publication

Structure and sequence of the myosin alkali light chain gene expressed in adult cardiac atria and fetal striated muscle.

01 Sep 1988

publication

Transcripts of alpha-cardiac and alpha-skeletal actins are early markers for myogenesis in the mouse embryo.

01 Mar 1988

publication

Detection of the nicotinic acetylcholine receptor alpha-subunit mRNA by in situ hybridization at neuromuscular junctions of 15-day-old chick striated muscles.

25 Feb 1988

publication

Functional activity of the two promoters of the myosin alkali light chain gene in primary muscle cell cultures: comparison with other muscle gene promoters and other culture systems.

01 Jan 1988

publication

Assignment of the human fast skeletal muscle myosin alkali light chains gene (MLC1F/MLC3F) to 2q 32.1-2qter.

10 Apr 1987

publication

Developmental pattern of mouse skeletal myosin heavy chain gene transcripts in vivo and in vitro.

01 Jan 1987

publication

Polymorphism of contractile proteins.

01 Dec 1986

publication

Actin and myosin multigene families: their expression during the formation and maturation of striated muscle.

01 Nov 1986

publication

Alpha-skeletal muscle actin mRNA’s accumulate in hypertrophied adult rat hearts.

01 Oct 1986

publication

A 5′ duplication of the alpha-cardiac actin gene in BALB/c mice is associated with abnormal levels of alpha-cardiac and alpha-skeletal actin mRNAs in adult cardiac tissue.

05 Feb 1986

publication

Simultaneous expression of skeletal muscle and heart actin proteins in various striated muscle tissues and cells. A quantitative determination of the two actin isoforms.

01 Jan 1986

publication

Comparison of three actin-coding sequences in the mouse; evolutionary relationships between the actin genes of warm-blooded vertebrates.

01 Nov 1985

publication

Genes for skeletal muscle myosin heavy chains are clustered and are not located on the same mouse chromosome as a cardiac myosin heavy chain gene.

15 Oct 1985

publication

The myosin alkali light chain proteins and their genes.

01 Aug 1985

publication

The same myosin alkali light chain gene is expressed in adult cardiac atria and in fetal skeletal muscle.

15 Jul 1985

publication

The myosin alkali light chains of mouse ventricular and slow skeletal muscle are indistinguishable and are encoded by the same gene.

11 Jul 1985

publication

A comparison between mammalian and avian fast skeletal muscle alkali myosin light chain genes: regulatory implications.

14 Mar 1985

publication

Investigation of genetic linkage between myosin and actin genes using an interspecific mouse back-cross.

14 Mar 1985

publication

Investigation of genetic linkage between myosin and actin genes using an interspecific mouse back-cross.

01 Jan 1985

publication

The actin and myosin multigene families.

01 Jan 1985

publication

Actin and myosin multigene families: their expression during the formation of skeletal muscle.

01 Nov 1984

publication

A single locus in the mouse encodes both myosin light chains 1 and 3, a second locus corresponds to a related pseudogene.

25 Nov 1983

publication

Sequential accumulation of mRNAs encoding different myosin heavy chain isoforms during skeletal muscle development in vivo detected with a recombinant plasmid identified as coding for an adult fast myosin heavy chain from mouse skeletal muscle.

15 Jun 1983

publication

Number and organization of actin-related sequences in the mouse genome.

01 Sep 1982

publication

Regulation of muscle gene expression. The accumulation of messenger RNAs coding for muscle-specific proteins during myogenesis in a mouse cell line.

01 Aug 1982

publication

A fetal skeletal muscle actin mRNA in the mouse and its identity with cardiac actin mRNA.

01 Apr 1982

publication

cDNA recombinant plasmid complementary to mRNAs for light chains 1 and 3 of mouse skeletal muscle myosin.

01 Jan 1982

publication

Analysis of the expression of myosin and actin genes during mouse myoblast differentiation using specific recombinant plasmids.

01 Jan 1982

publication

Skeletal muscle myogenesis: the expression of actin and myosin mRNAs.

10 Oct 1981

publication

There are approximately 20 actin gene in the human genome.

15 Sep 1981

publication

Length of the polyadenylated sequence in cytoplasmic ribonucleic acid isolated from fetal calf myoblasts differentiating in vitro.

01 May 1981

publication

A comparison between the synthesis of contractile proteins and the accumulation of their translatable mRNAs during calf myoblast differentiation.

25 Jan 1981

publication

Mouse actin messenger RNAs. Construction and characterization of a recombinant plasmid molecule containing a complementary DNA transcript of mouse alpha-actin mRNA.

01 Jan 1981

publication

Muscle coding sequences and their regulation during myogenesis: cloning of muscle actin cDNA probes.

15 Jul 1980

publication

Changes in gene expression during myogenic differentiation. I. Regulation of messenger RNA sequences expressed during myotube formation.

01 Jan 1979

publication

Biochemical aspects of muscle differentiation as analyzed by in vitro cultivation techniques.

01 Aug 1978

publication

A modified assay procedure for revealing the M form of creatine kinase in cultured muscle cells.

01 Jul 1978

publication

A skeletal muscle cell line isolated from a mouse teratocarcinoma undergoes apparently normal terminal differentiation in vitro.

01 Jan 1977

publication

Molecular aspects of myogenesis.

01 Jan 1977

publication

Messenger ribonucleic acid metabolism during myogenesis.

25 May 1976

publication

Cytoplasmic distribution of pulse-labelled poly(A)-containing RNA, particularly 26 S RNA, during myoblast growth and differentiation.

15 May 1975

publication

The use of metrizamide to separate cytoplasmic ribonucleoprotein particles in muscle cell cultures: a method for the isolation of messenger RNA, independent of its poly A content.

18 Jun 1974

publication

Effects of superoxide radicals on myoblast growth and differentiation.

01 Apr 1974

publication

The synthesis and stability of cytoplasmic messenger RNA during myoblast differentiation in culture.

01 Jan 1974

publication

Expression of the myosin gene in a hybrid cell derives from a rat myoblast and a mouse fibroblast.

01 Jan 1974

publication

[Mouse teratocarcinoma: isolation and characterization of two muscle cell lines (author’s transl)].

01 Aug 1972

publication

Changes in nuclear protein during the cell cycle in cultured mast cells separated by zonal centrifugation.

01 Aug 1971

publication

Changes in histone phosphorylation and associated early metabolic events in pig lymphocyte cultures transformed by phytohaemagglutinin or 6-N,2′-O-dibutyryladenosine 3′:5′-cyclic monophosphate.

01 Dec 1970

publication

The transformation of lymphccytes by adenosine 3′:5′-cyclic monophosphate, and consequent changes in histone microstructure.

01 Jun 1970

publication

A little guide for advanced search:

Cardiac progenitor cells of the first and second Heart Fields. Congenital Heart Diseases: The Broken Heart

Messenger RNA in differentiating muscle cells-my experience in François Gros’ lab in the 1970s and 80s.

M-Cadherin Is a PAX3 Target During Myotome Patterning.

In remembrance of David Yaffe.

Commentary on Distinct, but Previously Confused, Nrf1 Transcription Factors and Their Functions in Redox Regulation.

PAX3 Confers Functional Heterogeneity in Skeletal Muscle Stem Cell Responses to Environmental Stress.

The deployment of cell lineages that form the mammalian heart.

The role of Pitx2 and Pitx3 in muscle stem cells gives new insights into P38α MAP kinase and redox regulation of muscle regeneration

Gene regulatory networks and cell lineages that underlie the formation of skeletal muscle

Endothelial cell specification in the somite is compromised in Pax3-positive progenitors of Foxc1/2 conditional mutants, with loss of forelimb myogenesis.

Progressive developmental restriction, acquisition of left-right identity and cell growth behavior during lobe formation in mouse liver development

Tissue Differentiation: A Personal Account of Research on Myogenesis and Cardiogenesis.

First and second heart fields.

Fine-tuning the onset of myogenesis by homeobox proteins that interact with the Myf5 limb enhancer

PAX3 and PAX7 as upstream regulators of myogenesis

Clonal analysis reveals a common origin between nonsomite-derived neck muscles and heart myocardium.

Cardiac cell lineages that form the heart

Heart fields and cardiac morphogenesis

Interactions with John Gurdon–muscle as a mesodermal read-out and the community effect

Notch regulation of myogenic versus endothelial fates of cells that migrate from the somite to the limb

Redox regulation by Pitx2 and Pitx3 is critical for fetal myogenesis

Prdm1 functions in the mesoderm of the second heart field, where it interacts genetically with Tbx1, during outflow tract morphogenesis in the mouse embryo

Gene regulatory networks and transcriptional mechanisms that control myogenesis.

Lying low but ready for action: the quiescent muscle satellite cell

Resolving cell lineage contributions to the ventricular conduction system with a Cx40-GFP allele: a dual contribution of the first and second heart fields.

Itm2a is a Pax3 target gene, expressed at sites of skeletal muscle formation in vivo

Six homeoproteins directly activate Myod expression in the gene regulatory networks that control early myogenesis

Direct molecular regulation of the myogenic determination gene Myf5 by Pax3, with modulation by Six1/4 factors, is exemplified by the -111 kb-Myf5 enhancer

Quantitative analysis of polarity in 3D reveals local cell coordination in the embryonic mouse heart

Fibroblast growth factor 10 gene regulation in the second heart field by Tbx1, Nkx2-5, and Islet1 reveals a genetic switch for down-regulation in the myocardium

Sonic hedgehog acts cell-autonomously on muscle precursor cells to generate limb muscle diversity

Asymmetric fate of the posterior part of the second heart field results in unexpected left/right contributions to both poles of the heart

Lineage tree for the venous pole of the heart: clonal analysis clarifies controversial genealogy based on genetic tracing

Pax3( GFP ) , a new reporter for the melanocyte lineage, highlights novel aspects of PAX3 expression in the skin

Muscle satellite cells are primed for myogenesis but maintain quiescence with sequestration of Myf5 mRNA targeted by microRNA-31 in mRNP granules

Non conservation of function for the evolutionarily conserved prdm1 protein in the control of the slow twitch myogenic program in the mouse embryo

Studying the choreography of cardiogenesis. Interviewed by Ruth Williams

What does the concept of the stem cell niche really mean today?

Characterization of Pax3-expressing cells from adult blood vessels

Tracing cells for tracking cell lineage and clonal behavior

Lack of in vivo functional compensation between Pax family groups II and III in rodents

Transcriptome analyses based on genetic screens for Pax3 myogenic targets in the mouse embryo.

Megarole for microRNA in muscle disease.

Clonal analysis reveals common lineage relationships between head muscles and second heart field derivatives in the mouse embryo.

Developmental mechanisms, patterning and evolution.

Biphasic development of the mammalian ventricular conduction system.

A Pax3/Dmrt2/Myf5 regulatory cascade functions at the onset of myogenesis.

An adult tissue-specific stem cell in its niche: a gene profiling analysis of in vivo quiescent and activated muscle satellite cells.

Role of mesodermal FGF8 and FGF10 overlaps in the development of the arterial pole of the heart and pharyngeal arch arteries.

The formation of the embryonic mouse heart: heart fields and myocardial cell lineages.

How to make a heart: the origin and regulation of cardiac progenitor cells.

Pax3:Foxc2 reciprocal repression in the somite modulates muscular versus vascular cell fate choice in multipotent progenitors.

microRNAs gain magnitude in muscle.

Distinct and dynamic myogenic populations in the vertebrate embryo

Muscle stem cell behavior is modified by microRNA-27 regulation of Pax3 expression.

Landmarks and lineages in the developing heart.

The regulatory mechanisms that underlie inappropriate transcription of the myogenic determination gene Myf5 in the central nervous system.

Conotruncal defects associated with anomalous pulmonary venous connections.

The extracellular domain of Lrp5/6 inhibits noncanonical Wnt signaling in vivo.

Skeletal muscle differentiation of embryonic mesoangioblasts requires pax3 activity.

An FGF autocrine loop initiated in second heart field mesoderm regulates morphogenesis at the arterial pole of the heart.

Skeletal muscle stem cells.

Pax3 regulation of FGF signaling affects the progression of embryonic progenitor cells into the myogenic program.

Atrial myocardium derives from the posterior region of the second heart field, which acquires left-right identity as Pitx2c is expressed.

Myocardium at the base of the aorta and pulmonary trunk is prefigured in the outflow tract of the heart and in subdomains of the second heart field.

Integration of embryonic and fetal skeletal myogenic programs at the myosin light chain 1f/3f locus.

The A17 enhancer directs expression of Myf5 to muscle satellite cells but Mrf4 to myonuclei.

Six proteins regulate the activation of Myf5 expression in embryonic mouse limbs.

Beta catenin-independent activation of MyoD in presomitic mesoderm requires PKC and depends on Pax3 transcriptional activity.

An Nkx2-5/Bmp2/Smad1 negative feedback loop controls heart progenitor specification and proliferation.

The role of Pax genes in the development of tissues and organs: Pax3 and Pax7 regulate muscle progenitor cell functions.

Skeletal muscle progenitor cells and the role of Pax genes.

Myogenic progenitor cells in the mouse embryo are marked by the expression of Pax3/7 genes that regulate their survival and myogenic potential.

Myogenic progenitor cells and skeletal myogenesis in vertebrates.

A novel genetic hierarchy functions during hypaxial myogenesis: Pax3 directly activates Myf5 in muscle progenitor cells in the limb.

The Wnt/beta-catenin pathway regulates Gli-mediated Myf5 expression during somitogenesis.

Congenital heart defects in Fgfr2-IIIb and Fgf10 mutant mice.

Left and right ventricular contributions to the formation of the interventricular septum in the mouse heart.

Integrin alpha6beta1-laminin interactions regulate early myotome formation in the mouse embryo.