Timeline

Claude Roth

Permanent Researcher

03 Feb 2023

publication

Tocilizumab treated convalescent COVID-19 patients retain the cross-neutralization potential against SARS-CoV-2 variants.

09 Oct 2020

project

Study of immune crosstalk in COVID-19 COVIMUNE

21 Jun 2019

publication

A Modified mRNA Vaccine Targeting Immunodominant NS Epitopes Protects Against Dengue Virus Infection in HLA Class I Transgenic Mice

08 Oct 2018

project

T cell immunity to dengue virus infection in transgenic mice expressing human HLA molecules

08 Oct 2018

patent

A Zika virus chimeric polyepitope comprising non-structural proteins and its use in immunogenic composition (EP 17 306553.3)

07 Sep 2018

publication

Improved Immune Responses Against Zika Virus After Sequential Dengue and Zika Virus Infection in Humans

01 Aug 2018

publication

Host genetic control of mosquito-borne Flavivirus infections.

20 Apr 2018

event

Role of T and B cells in long lasting immunity against dengue

23 Feb 2018

publication

Immune Responses to Dengue and Zika Viruses-Guidance for T Cell Vaccine Development

01 Oct 2015

patent

A dengue virus chimeric polyepitope composed of fragments of non-structural proteins and its use in an immunogenic composition against dengue virus infection (E14305984.8)

20 Feb 2009

publication

Maturation of mouse NK cells is a 4-stage developmental program

11 Apr 2007

publication

Stromal-cell regulation of natural killer cell differentiation

04 Jun 2006

publication

Natural killer cell differentiation driven by Tyro3 receptor tyrosine kinases

01 Jun 2001

publication

Identification of committed NK cell progenitors in adult murine bone marrow

01 Jul 2000

publication

Clonal acquisition of inhibitory Ly49 receptors on developing NK cells is successively restricted and regulated by stromal class I MHC

01 Sep 1998

publication

Cancer immunotherapy by direct in vivo transfer of immunomodulatory genes

01 Dec 1996

publication

Gene therapy of spontaneous canine melanoma and feline fibrosarcoma by intratumoral administration of histoincompatible cells expressing human interleukin-2

01 Aug 1996

publication

Interleukin-10 inhibits tumor metastasis through an NK cell-dependent mechanism

01 Dec 1995

publication

Interleukin-2 and interleukin-4 display potent antitumour activity on rat medullary thyroid carcinoma cells

18 Aug 1995

publication

PCR-based analysis of the murine immunoglobulin heavy-chain repertoire

01 Mar 1995

publication

[Genetically modified cells as vectors of local secretion of cytokines. Perspectives in antitumoral immunotherapy]

01 Jan 1995

publication

Systemic antitumor effects of electrochemotherapy combined with histoincompatible cells secreting interleukin-2

01 Sep 1994

publication

Ly-49-independent inhibition of natural killer cell-mediated cytotoxicity by a soluble major histocompatibility complex class I molecule

01 Jan 1994

publication

Immune response against tumors

01 Aug 1993

publication

Identification of T cell peptides from C gamma 2ab involved in IgG2ab T cell-induced allotypic suppression. Relationship with the MHC haplotype of the suppressor T cell-donor Igha mice

01 Dec 1992

publication

Inhibition of tumor growth by histoincompatible cells expressing interleukin-2

01 Jan 1992

publication

[Inhibition of the tumoral growth induced by the injection of histo-incompatible cells producing interleukin-2]

01 Jan 1992

publication

[Potentiation of the antitumoral effect of electrochemotherapy by immunotherapy with allogeneic cells producing interleukin 2]

01 Jan 1992

publication

IL-2 gene transduction in malignant cells: applications in cancer containment

01 Nov 1990

publication

A novel approach to the induction of specific cytolytic T cells in vivo

01 Nov 1988

publication

IL-4, but not IL-5, can act synergistically with B cell activating factor (BCAF) to induce proliferation of resting B cells

01 Aug 1988

publication

Allogeneic manipulation of the GAT idiotypic cascade. Immunization of C57BL/6 mice by BALB/c anti-idiotypes stimulates similar strain-specific V genes as the original antigen

01 Apr 1988

publication

Biochemical characterization and biological effects of partially purified B cell-activating factor (BCAF)

01 Jan 1986

publication

Is there a germ-line network? The “GAT” case

01 Jul 1985

publication

Gene repertoire of the anti-poly(Glu60Ala30Tyr10) (GAT) immune response: comparison of VH, V kappa, and D regions used by anti-GAT antibodies and monoclonal antibodies produced after anti-idiotypic immunization

01 Jun 1985

publication

Immune response against poly(Glu60,Ala30,Tyr10) (GAT): immunization with monoclonal anti-idiotypic antibodies leads to the predominant stimulation of idiotypically similar immunoglobulins with anti-GAT activity

01 Apr 1985

publication

Induction by monoclonal anti-idiotypic antibodies of an anti-poly(Glu60 Ala30 Tyr10) (GAT) immune response in GAT-responder and GAT-nonresponder mice

01 Mar 1985

publication

Characterization of monoclonal antibodies against prostaglandin E2: fine specificity and neutralization of biological effects

01 Jan 1985

publication

The internal image and the structural idiotypic network (Ab1, Ab2, Ab3) in the GAT system

01 Jun 1984

publication

Poly(Glu60,Ala30,Tyr10) (GAT)-specific T cells do not express B cell public idiotopes but can be primed by monoclonal anti-idiotypic antibodies

01 Jan 1984

publication

Public idiotopes and/or internal images in the anti-poly(Glu60Ala30Tyr10) response: analysis by monoclonal antibodies

01 Jan 1984

publication

The use of monoclonal anti-idiotypic antibodies for studying antigen-specific T and B cell receptors

01 Dec 1983

publication

A little guide for advanced search:

Tocilizumab treated convalescent COVID-19 patients retain the cross-neutralization potential against SARS-CoV-2 variants.

Study of immune crosstalk in COVID-19 COVIMUNE

A Modified mRNA Vaccine Targeting Immunodominant NS Epitopes Protects Against Dengue Virus Infection in HLA Class I Transgenic Mice

T cell immunity to dengue virus infection in transgenic mice expressing human HLA molecules

A Zika virus chimeric polyepitope comprising non-structural proteins and its use in immunogenic composition (EP 17 306553.3)

Improved Immune Responses Against Zika Virus After Sequential Dengue and Zika Virus Infection in Humans

Host genetic control of mosquito-borne Flavivirus infections.

Role of T and B cells in long lasting immunity against dengue

Immune Responses to Dengue and Zika Viruses-Guidance for T Cell Vaccine Development

A dengue virus chimeric polyepitope composed of fragments of non-structural proteins and its use in an immunogenic composition against dengue virus infection (E14305984.8)

Maturation of mouse NK cells is a 4-stage developmental program

Stromal-cell regulation of natural killer cell differentiation

Natural killer cell differentiation driven by Tyro3 receptor tyrosine kinases

Identification of committed NK cell progenitors in adult murine bone marrow

Clonal acquisition of inhibitory Ly49 receptors on developing NK cells is successively restricted and regulated by stromal class I MHC

Cancer immunotherapy by direct in vivo transfer of immunomodulatory genes

Gene therapy of spontaneous canine melanoma and feline fibrosarcoma by intratumoral administration of histoincompatible cells expressing human interleukin-2

Interleukin-10 inhibits tumor metastasis through an NK cell-dependent mechanism

Interleukin-2 and interleukin-4 display potent antitumour activity on rat medullary thyroid carcinoma cells

PCR-based analysis of the murine immunoglobulin heavy-chain repertoire

[Genetically modified cells as vectors of local secretion of cytokines. Perspectives in antitumoral immunotherapy]

Systemic antitumor effects of electrochemotherapy combined with histoincompatible cells secreting interleukin-2

Ly-49-independent inhibition of natural killer cell-mediated cytotoxicity by a soluble major histocompatibility complex class I molecule

Immune response against tumors

Identification of T cell peptides from C gamma 2ab involved in IgG2ab T cell-induced allotypic suppression. Relationship with the MHC haplotype of the suppressor T cell-donor Igha mice

Inhibition of tumor growth by histoincompatible cells expressing interleukin-2

[Inhibition of the tumoral growth induced by the injection of histo-incompatible cells producing interleukin-2]

[Potentiation of the antitumoral effect of electrochemotherapy by immunotherapy with allogeneic cells producing interleukin 2]

IL-2 gene transduction in malignant cells: applications in cancer containment

A novel approach to the induction of specific cytolytic T cells in vivo

IL-4, but not IL-5, can act synergistically with B cell activating factor (BCAF) to induce proliferation of resting B cells

Allogeneic manipulation of the GAT idiotypic cascade. Immunization of C57BL/6 mice by BALB/c anti-idiotypes stimulates similar strain-specific V genes as the original antigen

Biochemical characterization and biological effects of partially purified B cell-activating factor (BCAF)

Is there a germ-line network? The “GAT” case

Gene repertoire of the anti-poly(Glu60Ala30Tyr10) (GAT) immune response: comparison of VH, V kappa, and D regions used by anti-GAT antibodies and monoclonal antibodies produced after anti-idiotypic immunization

Immune response against poly(Glu60,Ala30,Tyr10) (GAT): immunization with monoclonal anti-idiotypic antibodies leads to the predominant stimulation of idiotypically similar immunoglobulins with anti-GAT activity

Induction by monoclonal anti-idiotypic antibodies of an anti-poly(Glu60 Ala30 Tyr10) (GAT) immune response in GAT-responder and GAT-nonresponder mice

Characterization of monoclonal antibodies against prostaglandin E2: fine specificity and neutralization of biological effects

The internal image and the structural idiotypic network (Ab1, Ab2, Ab3) in the GAT system

Poly(Glu60,Ala30,Tyr10) (GAT)-specific T cells do not express B cell public idiotopes but can be primed by monoclonal anti-idiotypic antibodies

Public idiotopes and/or internal images in the anti-poly(Glu60Ala30Tyr10) response: analysis by monoclonal antibodies

The use of monoclonal anti-idiotypic antibodies for studying antigen-specific T and B cell receptors

Public and individual idiotopes in the anti-poly(Glu60, Ala30, Tyr10) response: analysis by monoclonal antibodies