Ligne de temps
Julia Chamot-Rooke
Responsable de Structure
18 mars 2024
publication
Cryo-EM structures of type IV pili complexed with nanobodies reveal immune escape mechanisms
Lire plus13 févr. 2024
publication
Do Not Waste Time─Ensure Success in Your Cross-Linking Mass Spectrometry Experiments before You Begin.
Lire plus26 mai 2023
publication
Comparing Top-Down Proteoform Identification: Deconvolution, PrSM Overlap, and PTM Detection.
Lire plus01 mai 2023
publication
Biological differences between FIM2 and FIM3 fimbriae of Bordetella pertussis: not just the serotype
Lire plus18 nov. 2021
publication
TDFragMapper: a visualization tool for evaluating experimental parameters in top-down proteomics.
Lire plus08 nov. 2021
29 sept. 2021
03 août 2021
publication
De Novo Sequencing of Antibody Light Chain Proteoforms from Patients with Multiple Myeloma.
Lire plus22 févr. 2021
publication
Advanced In Vivo Cross-Linking Mass Spectrometry Platform to Characterize Proteome-Wide Protein Interactions.
Lire plus23 déc. 2020
publication
Mass-spectrometry analysis of the human pineal proteome during night and day and in autism.
Lire plus10 nov. 2020
10 nov. 2020
09 nov. 2020
publication
ProteoCombiner: integrating bottom-up with top-down proteomics data for improved proteoform assessment.
Lire plus03 nov. 2020
publication
Toward Increased Reliability, Transparency, and Accessibility in Cross-linking Mass Spectrometry.
Lire plus05 oct. 2020
01 oct. 2020
publication
Optimization of a Top-Down Proteomics Platform for Closely Related Pathogenic Bacterial Discrimination.
Lire plus02 sept. 2020
publication
Interlaboratory Study for Characterizing Monoclonal Antibodies by Top-Down and Middle-Down Mass Spectrometry.
Lire plus02 juin 2020
publication
Extensive flavivirus E trimer breathing accompanies stem zippering of the post-fusion hairpin.
Lire plus02 juin 2020
publication
Structural basis for loading and inhibition of a bacterial T6SS phospholipase effector by the VgrG spike.
Lire plus05 févr. 2020
publication
Defective lytic transglycosylase disrupts cell morphogenesis by hindering cell wall de-O-acetylation in Neisseria meningitidis.
Lire plus21 janv. 2020
project
TopSpec : Next generation precision antibody profiling – from science fiction to reality
Lire plus01 oct. 2019
27 juin 2019
publication
Best practices and benchmarks for intact protein analysis for top-down mass spectrometry
Lire plus04 févr. 2019
publication
Top-Down Garbage Collector: a tool for selecting high-quality top-down proteomics mass spectra.
Lire plus25 oct. 2018
18 oct. 2018
publication
Consensus designs and thermal stability determinants of a human glutamate transporter
Lire plus15 oct. 2018
10 oct. 2018
14 août 2018
06 août 2018
publication
Characterization of LE3 and LE4, the only lytic phages known to infect the spirochete Leptospira.
Lire plus14 févr. 2018
02 févr. 2018
publication
Glycosylphosphatidylinositol Anchors from Galactomannan and GPI-Anchored Protein Are Synthesized by Distinct Pathways in Aspergillus fumigatus
Lire plus01 févr. 2018
publication
Characterization of homodimer interfaces with cross-linking mass spectrometry and isotopically labeled proteins
Lire plus12 janv. 2018
publication
Calcium-dependent disorder-to-order transitions are central to the secretion and folding of the CyaA toxin of Bordetella pertussis, the causative agent of whooping cough.
Lire plus21 mai 2017
publication
Prepore Stability Controls Productive Folding of the BAM-independent Multimeric Outer Membrane Secretin PulD.
Lire plus10 févr. 2017
publication
Stability, structural and functional properties of a monomeric, calcium-loaded adenylate cyclase toxin, CyaA, from Bordetella pertussis
Lire plus10 févr. 2017
06 janv. 2017
publication
Prepore Stability Controls Productive Folding of the BAM-independent Multimeric Outer Membrane Secretin PulD.
Lire plus23 août 2016
publication
Abundant Lysine Methylation and N-Terminal Acetylation in Sulfolobus islandicus Revealed by Bottom-Up and Top-Down Proteomics
Lire plus13 juil. 2016
publication
MEMHDX: an interactive tool to expedite the statistical validation and visualization of large HDX-MS datasets.
Lire plus05 juil. 2016
publication
Pseudopilin residue E5 is essential for recruitment by the type 2 secretion system assembly platform.
Lire plus23 févr. 2016
publication
Bio-guided identification of proteins for the diagnosis of cysticercosis in swine
Lire plus22 déc. 2015
publication
R vs. S fluoroproline ring substitution: trans/cis effects on the formation of b2 ions in gas-phase peptide fragmentation
Lire plus07 déc. 2015
publication
Evolution of Helicobacter: Acquisition by Gastric Species of Two Histidine-Rich Proteins Essential for Colonization
Lire plus01 nov. 2015
29 oct. 2015
publication
Changes in markers associated with dendritic cells driving the differentiation of either TH2 cells or regulatory T cells correlate with clinical benefit during allergen immunotherapy.
Lire plus16 sept. 2015
publication
Structural models of intrinsically disordered and calcium-bound folded states of a protein adapted for secretion.
Lire plus14 sept. 2015
publication
Neisseria meningitidis Type IV Pili Composed of Sequence Invariable Pilins Are Masked by Multisite Glycosylation
Lire plus08 juil. 2015
03 juil. 2015
11 mai 2015
15 avr. 2015
publication
Conserved Streptococcus pneumoniae spirosomes suggest a single type of transformation pilus in competence
Lire plus12 janv. 2015
publication
A novel bio-orthogonal cross-linker for improved protein/protein interaction analysis
Lire plus01 oct. 2014
publication
Robust and low cost uniform (15)N-labeling of proteins expressed in Drosophila S2 cells and Spodoptera frugiperda Sf9 cells for NMR applications.
Lire plus15 juin 2014
publication
Ion source parameters and hydrogen scrambling in the ECD of selectively deuterated peptides
Lire plus05 mai 2014
publication
O-Glycosylation of the N-terminal region of the serine-rich adhesin Srr1 of Streptococcus agalactiae explored by mass spectrometry
Lire plus01 mai 2014
publication
IR action spectroscopy shows competitive oxazolone and diketopiperazine formation in peptides depends on peptide length and identity of terminal residue in the departing fragment
Lire plus16 avr. 2014
publication
Proteomic analysis of intact flagella of procyclic Trypanosoma brucei cells identifies novel flagellar proteins with unique sub-localization and dynamics
Lire plus12 mars 2014
publication
Complete posttranslational modification mapping of pathogenic Neisseria meningitidis pilins requires top-down mass spectrometry
Lire plus01 nov. 2013
publication
A combined mass spectrometry strategy for complete posttranslational modification mapping of Neisseria meningitidis major pilin
Lire plus27 juin 2013
publication
A type IV pilus mediates DNA binding during natural transformation in Streptococcus pneumoniae
Lire plus14 avr. 2013
publication
Identification and functional characterization of a novel α-conotoxin (EIIA) from Conus ermineus
Lire plus01 mars 2013
06 févr. 2013
publication
Influence of N-terminal residue composition on the structure of proline-containing b2+ ions
Lire plus24 avr. 2012
publication
Structural influences on preferential oxazolone versus diketopiperazine b(2+) ion formation for histidine analogue-containing peptides
Lire plus06 mars 2012
publication
Assigning structures to gas-phase peptide cations and cation-radicals. An infrared multiphoton dissociation, ion mobility, electron transfer, and computational study of a histidine peptide ion
Lire plus04 juin 2011
publication
Dissociation channel dependence on peptide size observed in electron capture dissociation of tryptic peptides
Lire plus11 févr. 2011
publication
Posttranslational modification of pili upon cell contact triggers N. meningitidis dissemination
Lire plus01 nov. 2010
publication
Identification of a novel snake peptide toxin displaying high affinity and antagonist behaviour for the α2-adrenoceptors
Lire plus11 août 2010
publication
The histidine effect. Electron transfer and capture cause different dissociations and rearrangements of histidine peptide cation-radicals
Lire plus01 août 2010
02 avr. 2010
publication
Separation and identification of structural isomers by quadrupole collision-induced dissociation-hydrogen/deuterium exchange-infrared multiphoton dissociation (QCID-HDX-IRMPD)
Lire plus01 déc. 2009
31 déc. 2008
21 oct. 2008
publication
Structure of electron-capture dissociation fragments from charge-tagged peptides probed by tunable infrared multiple photon dissociation
Lire plus01 nov. 2007
18 sept. 2007
publication
Electron capture in charge-tagged peptides. Evidence for the role of excited electronic states
Lire plus05 sept. 2007
publication
Alternative Neisseria spp. type IV pilin glycosylation with a glyceramido acetamido trideoxyhexose residue
Lire plus25 avr. 2007
publication
The combination of electron capture dissociation and fixed charge derivatization increases sequence coverage for O-glycosylated and O-phosphorylated peptides
Lire plus30 mars 2006
01 mars 2006
publication
Proteomic analysis of the tetraspanin web using LC-ESI-MS/MS and MALDI-FTICR-MS
Lire plus15 oct. 2005
publication
Characterization of toxins within crude venoms by combined use of Fourier transform mass spectrometry and cloning
Lire plus01 nov. 1975
publication