The fundamental unit of life is the cell. Only a profound understanding of the structure and function of cells —either as single units or in the context of tissues and the whole organism— will allow an understanding of what derails in pathological conditions and provide means to prevent those. Our goal is a quantitative and comprehensive characterization and ultimately predictive understanding of the cellular processes at multiple scales, in physiological and pathological conditions. This knowledge is essential for the development of successful translational research strategies, in the context of infection or in other cellular-based pathologies such as cancer and neurodegenerative diseases.
The main themes that we are exploring are:
• Cell division
• Cell migration
• Host-pathogen interactions with a focus on intracellular traffic, epigenetic, metabolism, cytoskeletal and membrane remodeling
• Cancer
• Cell metabolism
• Function and traffic of intracellular organelles
• Advanced microscopy and imaging, including image analysis
• Cell-cell communication and collective behavior
• Evolution of morphogenesis
The UMR 3691 is directed by Agathe Subtil and Arnaud Echard acts as deputy director.
