Pour plus d’informations sur la plateforme, voir la page web en anglais :
https://research.pasteur.fr/en/team/fabrice-agou-team/
(19/01/2018)
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Équipements
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Array
Echo Liquid Handler System • Labcyte • Echo 550
The Echo 550 instrument enables non-contact liquid handling using sound energy, high speed, contamination-free transfer of cDNA, siRNA vectors, proteins and crystallography reagents – in nanoliter increments. Echo Plate Reformat software offers a variety […]
Octet Instrument • ForteBio • Octet HTX System
The Octet HTX instrument monitors up to 96 biosensors simultaneously, enabling label-free detection for protein quantitation and kinetic characterization at unmatched speed. The system’s ability to read 8, 16, 32, 48 or 96 wells […]
Microscope • Olympus • IX83
The fully motorized IX83 is the most advanced member of the IX3 series of inverted imaging systems and offers a new level of application flexibility. Choose from the one-deck system with a low, ergonomic […]
Microscope • Optical Biosystems • StellarVision
Target-based, cell-based and phenotypic/microscopy screening assay have numerous advantages and disadvantages and an important challenge in the near future will be to effectively incorporate new screening technologies into phenotypic screening approaches since the traditional […]
Plate Reader • Wyatt Technology • DynaPro Plate Reader II
For small molecules, the DynaPro Plate Reader II can easily detect compound aggregates and aggregation inducers which often result from High-Throughput Screening (HTS) campaign. These primary Hits are often considered as false-positives with poor […]
Membres
Fabrice Agou
Responsable de Plateforme
Responsable
Anciens Membres
2000
2000
Name
Position
2015
2020
Laurianne Davignon
Post-doc
2015
2020
Elisabeth Fontan
2015
2020
Keïs Nabhane Said Halidi
2015
2020
Sara Consalvi
Post-doc
2015
2020
Marine Charpentier
Post-doc
2015
2020
Emmanuel Laplantine
Group Leader
Projet Transversal
Financements
Publications
Télécharger-
2020Large Scale Active-Learning-Guided Exploration for in Vitro Protein Production Optimization, Nat Commun. 2020 Apr 20;11(1):1872.
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2019Two NEMO-like Ubiquitin-Binding Domains in CEP55 Differently Regulate Cytokinesis., iScience. 2019 Sep 25;20:292-309.
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2018CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair., Nat Commun. 2018 Mar 19;9(1):1133.
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2018An Attractive Reelin Gradient Establishes Synaptic Lamination in the Vertebrate Visual System, Neuron. 2018 Feb 5. pii: S0896-6273(18)30055-2..
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2018TALEN-Induced Double-Strand Break Repair of CTG Trinucleotide Repeats., Cell Rep. 2018 Feb 20;22(8):2146-2159.
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2017Argonaute proteins regulate HIV-1 multiply spliced RNA and viral production in a Dicer independent manner, Nucleic Acids Res. 2017 Apr;45(7):4158-4173.
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2017Lack of interaction between NEMO and SHARPIN impairs linear ubiquitination and NF-κB activation and leads to incontinentia pigmenti., J Allergy Clin Immunol. 2017 Dec;140(6):1671-1682.e2.
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2017Intracellular growth of Mycobacterium tuberculosis after macrophage cell death leads to serial killing of host cells., Elife. 2017 May 5;6. pii: e28205.
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2017Single-Molecule Analysis of mtDNA Replication Uncovers the Basis of the Common Deletion, Mol. Cell 2017 Feb;65(3):527-538.e6.
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2016HIV Cell-to-Cell Spread Results in Earlier Onset of Viral Gene Expression by Multiple Infections per Cell, PLoS Pathog. 2016 Nov 3;12(11):e1005964.
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Contact
Phone: +33 (0)1 40 61 38 10
Email: pfccb@pasteur.fr
Address
25-28 Rue du Docteur Roux
75015, Paris
France