• 2021
  Luke K. McKenzie, Marie Flamme, Patrick S. Felder, Johannes Karges, Frederic Bonhomme, Albert Gandioso, Christian Malosse, Gilles Gasser*, Marcel Hollenstein*, A ruthenium-oligonucleotide bioconjugated photosensitizing aptamer for cancer cell specific photodynamic therapy, ChemRxiv 2021, 10.33774/chemrxiv-2021-5n9xv.
• 2021
  Czernecki D, Bonhomme F, Kaminski PA, Delarue M, , Characterization of a triad of genes in cyanophage S-2L sufficient to replace adenine by 2-aminoadenine in bacterial DNA., Nat Commun 2021 08; 12(1): 4710.
• 2021
  Nardella F, Halby L, Dobrescu I, Viluma J, Bon C, Claes A, Cadet-Daniel V, Tafit A, Roesch C, Hammam E, Erdmann D, Mairet-Khedim M, Peronet R, Mecheri S, Witkowski B, Scherf A, Arimondo PB, , Procainamide-SAHA Fused Inhibitors of hHDAC6 Tackle Multidrug-Resistant Malaria Parasites., J Med Chem 2021 Jul; 64(14): 10403-10417.
• 2021
  Lobo J, Cardoso AR, Miranda-Gonçalves V, Looijenga LHJ, Lopez M, Arimondo PB, Henrique R, Jerónimo C, , Targeting Germ Cell Tumors with the Newly Synthesized Flavanone-Derived Compound MLo1302 Efficiently Reduces Tumor Cell Viability and Induces Apoptosis and Cell Cycle Arrest., Pharmaceutics 2021 Jan; 13(1): .
• 2020
  Corentin BON, Ludovic Halby, Paola B. Arimondo, Bisubstrate inhibitors: the promise of a selective and potent chemical inhibition of epigenetic ‘writers’, Epigenomics, Sep. 2020.
• 2020
  Bon C, Halby L, Arimondo PB, , Bisubstrate inhibitors: the promise of a selective and potent chemical inhibition of epigenetic ‘writers’., Epigenomics 2020 Sep; 12(17): 1479-1482.
• 2020
  CorentinBon,YangSi, Paola B.Arimondo, Chapter 4 – Targeting DOT1L for mixed-lineage rearranged leukemia, Histone Modifications in Therapy, Translational Epigenetics 2020.
• 2020
  Topart C, Werner E, Arimondo PB, , Wandering along the epigenetic timeline., Clin Epigenetics 2020 07; 12(1): 97.
• 2020
  Castillo-Aguilera O; Depreux P; Ballée A; Beaurain F; Arimondo PB; Goossens L , Study of the Effect of Substituents of ortho-Phenylenediamines in the Opening of Lactones and Lactams for Access to Benzimidazol-2-yl Alkanols and Benzimidazol-2-yl Alkylamines., SynLett 2020 31.
• 2020
  Pechalrieu D, Assemat F, Halby L, Marcellin M, Yan P, Chaoui K, Sharma S, Chiosis G, Burlet-Schiltz O, Arimondo PB, Lopez M, , Bisubstrate-Type Chemical Probes Identify GRP94 as a Potential Target of Cytosine-Containing Adenosine Analogs., ACS Chem Biol 2020 04; 15(4): 952-961.
• 2020
  Zwergel C, Fioravanti R, Stazi G, Sarno F, Battistelli C, Romanelli A, Nebbioso A, Mendes E, Paulo A, Strippoli R, Tripodi M, Pechalrieu D, Arimondo PB, De Luca T, Del Bufalo D, Trisciuoglio D, Altucci L, Valente S, Mai A, Novel Quinoline Compounds Active in Cancer Cells through Coupled DNA Methyltransferase Inhibition and Degradation, Cancers (Basel) 2020 Feb;12(2).
• 2020
  Nardella F, Halby L, Hammam E, Erdmann D, Cadet-Daniel V, Peronet R, Ménard D, Witkowski B, Mecheri S, Scherf A, Arimondo PB, , DNA Methylation Bisubstrate Inhibitors Are Fast-Acting Drugs Active against Artemisinin-Resistant Plasmodium falciparum Parasites., ACS Cent Sci 2020 Jan; 6(1): 16-21.
• 2019
  Ganesan A, Arimondo PB, Rots MG, Jeronimo C, Berdasco M, The timeline of epigenetic drug discovery: from reality to dreams, Clin Epigenetics 2019 12;11(1):174.
• 2019
  Pechalrieu D, Dauzonne D, Arimondo PB, Lopez M, , Synthesis of novel 3-halo-3-nitroflavanones and their activities as DNA methyltransferase inhibitors in cancer cells., Eur J Med Chem 2020 Jan; 186(): 111829.
• 2019
  Bon C, Erdmann D, Halby L, Arimondo PB, , [Chemical targeting of DNA and histone methylation in cancer: Novelties, hopes and promises]., Bull Cancer 2019 Oct; 106(10): 823-833.
• 2019
  Arimondo PB, Barberousse A, Pontarotti G., The Many Faces of Epigenetics, Oxford, December 2017, Epigenetics 2019 Apr 17:1-9.
• 2019
  Desjobert C, Carrier A, Delmas A, Marzese DM, Daunay A, Busato F, Pillon A, Tost J, Riond J, Favre G, Etievant C, Arimondo PB, Demethylation by low-dose 5-aza-2′-deoxycytidine impairs 3D melanoma invasion partially through miR-199a-3p expression revealing the role of this miR in melanoma, Clin Epigenetics 2019 Jan;11(1):9.
• 2019
  Franchini DM, Lanvin O, Tosolini M, Patras de Campaigno E, Cammas A, Péricart S, Scarlata CM, Lebras M, Rossi C, Ligat L, Pont F, Arimondo PB, Laurent C, Ayyoub M, Despas F, Lapeyre-Mestre M, Millevoi S, Fournié JJ, Microtubule-Driven Stress Granule Dynamics Regulate Inhibitory Immune Checkpoint Expression in T Cells, Cell Rep 2019 Jan;26(1):94-107.e7.
• 2019
  Lecourt C, Dhambri S, Yamani K, Boissonnat G, Specklin S, Fleury E, Hammad K, Auclair E, Sablé S, Grondin A, Arimondo PB, Sautel F, Massiot G, Meyer C, Cossy J, Sorin G, Lannou MI, Ardisson J, Assembly of the Entire Carbon Backbone of a Stereoisomer of the Antitumor Marine Natural Product Hemicalide, Chemistry 2019 Jan;.
• 2018
  Lascano S, Lopez M, Arimondo PB, Natural Products and Chemical Biology Tools: Alternatives to Target Epigenetic Mechanisms in Cancers, Chem Rec 2018 Dec;18(12):1854-1876.
• 2018
  Bouchut A, Rotili D, Pierrot C, Valente S, Lafitte S, Schultz J, Hoglund U, Mazzone R, Lucidi A, Fabrizi G, Pechalrieu D, Arimondo PB, Skinner-Adams TS, Chua MJ, Andrews KT, Mai A, Khalife J, Identification of novel quinazoline derivatives as potent antiplasmodial agents, Eur J Med Chem 2019 Jan;161:277-291.
• 2018
  Manara MC, Valente S, Cristalli C, Nicoletti G, Landuzzi L, Zwergel C, Mazzone R, Stazi G, Arimondo PB, Pasello M, Guerzoni C, Picci P, Nanni P, Lollini PL, Mai A, Scotlandi K, A Quinoline-Based DNA Methyltransferase Inhibitor as a Possible Adjuvant in Osteosarcoma Therapy, Mol. Cancer Ther. 2018 Sep;17(9):1881-1892.
• 2018
  Geel TM, Ruiters MHJ, Cool RH, Halby L, Voshart DC, Andrade Ruiz L, Niezen-Koning KE, Arimondo PB, Rots MG, The past and presence of gene targeting: from chemicals and DNA via proteins to RNA, Philos. Trans. R. Soc. Lond., B, Biol. Sci. 2018 Jun;373(1748).
• 2018
  Halby L, Marechal N, Pechalrieu D, Cura V, Franchini DM, Faux C, Alby F, Troffer-Charlier N, Kudithipudi S, Jeltsch A, Aouadi W, Decroly E, Guillemot JC, Page P, Ferroud C, Bonnefond L, Guianvarc'h D, Cavarelli J, Arimondo PB, , , Philos Trans R Soc Lond B Biol Sci 2018 06; 373(1748): .
• 2018
  Emperle M, Rajavelu A, Kunert S, Arimondo PB, Reinhardt R, Jurkowska RZ, Jeltsch A, The DNMT3A R882H mutant displays altered flanking sequence preferences, Nucleic Acids Res. 2018 Apr;46(6):3130-3139.
• 2018
  Zhang D, Markoulides MS, Stepanovs D, Rydzik AM, El-Hussein A, Bon C, Kamps JJAG, Umland KD, Collins PM, Cahill ST, Wang DY, von Delft F, Brem J, McDonough MA, Schofield CJ, Structure activity relationship studies on rhodanines and derived enethiol inhibitors of metallo-β-lactamases, Bioorg. Med. Chem. 2018 07;26(11):2928-2936.
• 2018
  Sabatino M, Rotili D, Patsilinakos A, Forgione M, Tomaselli D, Alby F, Arimondo PB, Mai A, Ragno R, Disruptor of telomeric silencing 1-like (DOT1L): disclosing a new class of non-nucleoside inhibitors by means of ligand-based and structure-based approaches, J. Comput. Aided Mol. Des. 2018 Mar;32(3):435-458.
• 2017
  Rondelet G, Fleury L, Faux C, Masson V, Dubois J, Arimondo PB, Willems L, Wouters J, Inhibition studies of DNA methyltransferases by maleimide derivatives of RG108 as non-nucleoside inhibitors, Future Med Chem 2017 09;9(13):1465-1481.
• 2017
  Halby L, Menon Y, Rilova E, Pechalrieu D, Masson V, Faux C, Bouhlel MA, David-Cordonnier MH, Novosad N, Aussagues Y, Samson A, Lacroix L, Ausseil F, Fleury L, Guianvarc'h D, Ferroud C, Arimondo PB, Rational Design of Bisubstrate-Type Analogues as Inhibitors of DNA Methyltransferases in Cancer Cells, J. Med. Chem. 2017 06;60(11):4665-4679.
• 2017
  Daly HC, Sampedro G, Bon C, Wu D, Ismail G, Cahill RA, O'Shea DF, BF-azadipyrromethene NIR-emissive fluorophores with research and clinical potential, Eur J Med Chem 2017 Jul;135:392-400.
• 2017
  Castillo-Aguilera O, Depreux P, Halby L, Arimondo PB, Goossens L, DNA Methylation Targeting: The DNMT/HMT Crosstalk Challenge, Biomolecules 2017 01;7(1).
• 2016
  Pechalrieu D, Etievant C, Arimondo PB, DNA methyltransferase inhibitors in cancer: From pharmacology to translational studies, Biochem. Pharmacol. 2017 04;129:1-13.
• 2016
  Gregoire JM, Fleury L, Salazar-Cardozo C, Alby F, Masson V, Arimondo PB, Ausseil F, Identification of epigenetic factors regulating the mesenchyme to epithelium transition by RNA interference screening in breast cancer cells, BMC Cancer 2016 08;16:700.
• 2016
  Erdmann A, Menon Y, Gros C, Masson V, Aussagues Y, Ausseil F, Novosad N, Schambel P, Baltas M, Arimondo PB, Identification and optimization of hydrazone-gallate derivatives as specific inhibitors of DNA methyltransferase 3A, Future Med Chem 2016;8(4):373-80.
• 2016
  Lopez M, Halby L, Arimondo PB, DNA Methyltransferase Inhibitors: Development and Applications, Adv. Exp. Med. Biol. 2016;945:431-473.
• 2015
  Erdmann A, Menon Y, Gros C, Molinier N, Novosad N, Samson A, Gregoire JM, Long C, Ausseil F, Halby L, Arimondo PB, Design and synthesis of new non nucleoside inhibitors of DNMT3A, Bioorg. Med. Chem. 2015 Sep;23(17):5946-53.
• 2015
  Vispé S, Deroide A, Davoine E, Desjobert C, Lestienne F, Fournier L, Novosad N, Bréand S, Besse J, Busato F, Tost J, De Vries L, Cussac D, Riond J, Arimondo PB, Consequences of combining siRNA-mediated DNA methyltransferase 1 depletion with 5-aza-2′-deoxycytidine in human leukemic KG1 cells, Oncotarget 2015 Jun;6(17):15265-82.
• 2015
  Desjobert C, El Maï M, Gérard-Hirne T, Guianvarc'h D, Carrier A, Pottier C, Arimondo PB, Riond J, Combined analysis of DNA methylation and cell cycle in cancer cells, Epigenetics 2015;10(1):82-91.
• 2015
  Moison C, Assemat F, Daunay A, Arimondo PB, Tost J, DNA Methylation Analysis of ChIP Products at Single Nucleotide Resolution by Pyrosequencing®, Methods Mol. Biol. 2015;1315:315-33.
• 2014
  Gros C, Fleury L, Nahoum V, Faux C, Valente S, Labella D, Cantagrel F, Rilova E, Bouhlel MA, David-Cordonnier MH, Dufau I, Ausseil F, Mai A, Mourey L, Lacroix L, Arimondo PB, New insights on the mechanism of quinoline-based DNA Methyltransferase inhibitors, J. Biol. Chem. 2015 Mar;290(10):6293-302.
• 2014
  Erdmann A, Halby L, Fahy J, Arimondo PB, Targeting DNA methylation with small molecules: what’s next?, J. Med. Chem. 2015 Mar;58(6):2569-83.
• 2014
  Pouny I, Batut M, Vendier L, David B, Yi S, Sautel F, Arimondo PB, Massiot G, Cytisine-like alkaloids from Ormosia hosiei Hemsl. & E.H. Wilson, Phytochemistry 2014 Nov;107:97-101.
• 2014
  Guianvarc'h D, Arimondo PB, Challenges in developing novel DNA methyltransferases inhibitors for cancer therapy, Future Med Chem 2014 Jul;6(11):1237-40.
• 2014
  Rotili D, Tarantino D, Marrocco B, Gros C, Masson V, Poughon V, Ausseil F, Chang Y, Labella D, Cosconati S, Di Maro S, Novellino E, Schnekenburger M, Grandjenette C, Bouvy C, Diederich M, Cheng X, Arimondo PB, Mai A, Properly substituted analogues of BIX-01294 lose inhibition of G9a histone methyltransferase and gain selective anti-DNA methyltransferase 3A activity, PLoS ONE 2014;9(5):e96941.
• 2014
  Rilova E, Erdmann A, Gros C, Masson V, Aussagues Y, Poughon-Cassabois V, Rajavelu A, Jeltsch A, Menon Y, Novosad N, Gregoire JM, Vispé S, Schambel P, Ausseil F, Sautel F, Arimondo PB, Cantagrel F, Design, synthesis and biological evaluation of 4-amino-N- (4-aminophenyl)benzamide analogues of quinoline-based SGI-1027 as inhibitors of DNA methylation, ChemMedChem 2014 Mar;9(3):590-601.
• 2014
  Moison C, Assemat F, Daunay A, Tost J, Guieysse-Peugeot AL, Arimondo PB, Synergistic chromatin repression of the tumor suppressor gene RARB in human prostate cancers, Epigenetics 2014 Apr;9(4):477-82.
• 2014
  Valente S, Liu Y, Schnekenburger M, Zwergel C, Cosconati S, Gros C, Tardugno M, Labella D, Florean C, Minden S, Hashimoto H, Chang Y, Zhang X, Kirsch G, Novellino E, Arimondo PB, Miele E, Ferretti E, Gulino A, Diederich M, Cheng X, Mai A, Selective non-nucleoside inhibitors of human DNA methyltransferases active in cancer including in cancer stem cells, J. Med. Chem. 2014 Feb;57(3):701-13.
• 2014
  Asgatay S, Champion C, Marloie G, Drujon T, Senamaud-Beaufort C, Ceccaldi A, Erdmann A, Rajavelu A, Schambel P, Jeltsch A, Lequin O, Karoyan P, Arimondo PB, Guianvarc'h D, Synthesis and evaluation of analogues of N-phthaloyl-l-tryptophan (RG108) as inhibitors of DNA methyltransferase 1, J. Med. Chem. 2014 Jan;57(2):421-34.
• 2013
  Gros C, Chauvigné L, Poulet A, Menon Y, Ausseil F, Dufau I, Arimondo PB, Development of a universal radioactive DNA methyltransferase inhibition test for high-throughput screening and mechanistic studies, Nucleic Acids Res. 2013 Oct;41(19):e185.
• 2013
  Long C, Aussagues Y, Molinier N, Marcourt L, Vendier L, Samson A, Poughon V, Chalo Mutiso PB, Ausseil F, Sautel F, Arimondo PB, Massiot G, Dichapetalins from Dichapetalum species and their cytotoxic properties, Phytochemistry 2013 Oct;94:184-91.
• 2013
  Ceccaldi A, Rajavelu A, Ragozin S, Sénamaud-Beaufort C, Bashtrykov P, Testa N, Dali-Ali H, Maulay-Bailly C, Amand S, Guianvarc'h D, Jeltsch A, Arimondo PB, Identification of novel inhibitors of DNA methylation by screening of a chemical library, ACS Chem. Biol. 2013 Mar;8(3):543-8.
• 2013
  Moison C, Senamaud-Beaufort C, Fourrière L, Champion C, Ceccaldi A, Lacomme S, Daunay A, Tost J, Arimondo PB, Guieysse-Peugeot AL, DNA methylation associated with polycomb repression in retinoic acid receptor β silencing, FASEB J. 2013 Apr;27(4):1468-78.
• 2012
  Fahy J, Jeltsch A, Arimondo PB, DNA methyltransferase inhibitors in cancer: a chemical and therapeutic patent overview and selected clinical studies, Expert Opin Ther Pat 2012 Dec;22(12):1427-42.
• 2012
  Arimondo PB, Egger G, Tost J, Epigenetics, Biochimie 2012 Nov;94(11):2191-2.
• 2012
  Gros C, Fahy J, Halby L, Dufau I, Erdmann A, Gregoire JM, Ausseil F, Vispé S, Arimondo PB, DNA methylation inhibitors in cancer: recent and future approaches, Biochimie 2012 Nov;94(11):2280-96.
• 2011
  Vekhoff P, Duca M, Guianvarc'h D, Benhida R, Arimondo PB, Sequence-specific base pair mimics are efficient topoisomerase IB inhibitors, Biochemistry 2012 Jan;51(1):43-51.
• 2011
  Halby L, Champion C, Sénamaud-Beaufort C, Ajjan S, Drujon T, Rajavelu A, Ceccaldi A, Jurkowska R, Lequin O, Nelson WG, Guy A, Jeltsch A, Guianvarc'h D, Ferroud C, Arimondo PB, Rapid synthesis of new DNMT inhibitors derivatives of procainamide, Chembiochem 2012 Jan;13(1):157-65.
• 2011
  Beck J, Guminski Y, Long C, Marcourt L, Derguini F, Plisson F, Grondin A, Vandenberghe I, Vispé S, Brel V, Aussagues Y, Ausseil F, Arimondo PB, Massiot G, Sautel F, Cantagrel F, Semisynthetic neoboutomellerone derivatives as ubiquitin-proteasome pathway inhibitors, Bioorg. Med. Chem. 2012 Jan;20(2):819-31.
• 2011
  Bensasson RV, Zoete V, Jossang A, Bodo B, Arimondo PB, Land EJ, Potency of inhibition of human DNA topoisomerase I by flavones assessed through physicochemical parameters, Free Radic. Biol. Med. 2011 Oct;51(7):1406-10.
• 2011
  Moison C, Arimondo PB, Guieysse-Peugeot AL, Commercial reverse transcriptase as source of false-positive strand-specific RNA detection in human cells, Biochimie 2011 Oct;93(10):1731-7.
• 2011
  Ceccaldi A, Rajavelu A, Champion C, Rampon C, Jurkowska R, Jankevicius G, Sénamaud-Beaufort C, Ponger L, Gagey N, Ali HD, Tost J, Vriz S, Ros S, Dauzonne D, Jeltsch A, Guianvarc'h D, Arimondo PB, C5-DNA methyltransferase inhibitors: from screening to effects on zebrafish embryo development, Chembiochem 2011 Jun;12(9):1337-45.
• 2011
  Pitts SL, Jablonksy MJ, Duca M, Dauzonne D, Monneret C, Arimondo PB, Anklin C, Graves DE, Osheroff N, Contributions of the D-Ring to the activity of etoposide against human topoisomerase IIα: potential interactions with DNA in the ternary enzyme–drug–DNA complex, Biochemistry 2011 Jun;50(22):5058-66.
• 2011
  Le Breton C, Hennion M, Arimondo PB, Hyrien O, Replication-fork stalling and processing at a single psoralen interstrand crosslink in Xenopus egg extracts, PLoS ONE 2011 Apr;6(4):e18554.
• 2011
  Jurkowska RZ, Ceccaldi A, Zhang Y, Arimondo PB, Jeltsch A, DNA methyltransferase assays, Methods Mol. Biol. 2011;791:157-77.
• 2010
  Braslau A, van Noort J, Arimondo PB, Introduction “DNA and chromosomes: Physical and biological approaches”, Biochimie 2010 Dec;92(12):v-vi.
• 2010
  Champion C, Guianvarc'h D, Sénamaud-Beaufort C, Jurkowska RZ, Jeltsch A, Ponger L, Arimondo PB, Guieysse-Peugeot AL, Mechanistic insights on the inhibition of c5 DNA methyltransferases by zebularine, PLoS ONE 2010 Aug;5(8):e12388.
• 2010
  Miroglio A, Jammes H, Tost J, Ponger L, Gut IG, El Abdalaoui H, Coste J, Chaussade S, Arimondo PB, Lamarque D, Dandolo L, Specific hypomethylated CpGs at the IGF2 locus act as an epigenetic biomarker for familial adenomatous polyposis colorectal cancer, Epigenomics 2010 Jun;2(3):365-75.
• 2010
  Oussedik K, François JC, Halby L, Senamaud-Beaufort C, Toutirais G, Dallavalle S, Pommier Y, Pisano C, Arimondo PB, Sequence-specific targeting of IGF-I and IGF-IR genes by camptothecins, FASEB J. 2010 Jul;24(7):2235-44.
• 2009
  Vekhoff P, Halby L, Oussedik K, Dallavalle S, Merlini L, Mahieu C, Lansiaux A, Bailly C, Boutorine A, Pisano C, Giannini G, Alloatti D, Arimondo PB, Optimized synthesis and enhanced efficacy of novel triplex-forming camptothecin derivatives based on gimatecan, Bioconjug. Chem. 2009 Apr;20(4):666-72.
• 2008
  Vekhoff P, Ceccaldi A, Polverari D, Pylouster J, Pisano C, Arimondo PB, Triplex formation on DNA targets: how to choose the oligonucleotide, Biochemistry 2008 Nov;47(47):12277-89.
• 2008
  Duca M, Vekhoff P, Oussedik K, Halby L, Arimondo PB, The triple helix: 50 years later, the outcome, Nucleic Acids Res. 2008 Sep;36(16):5123-38.
• 2008
  Stierlé V, Duca M, Halby L, Senamaud-Beaufort C, Capobianco ML, Laigle A, Jollès B, Arimondo PB, Targeting MDR1 gene: synthesis and cellular study of modified daunomycin-triplex-forming oligonucleotide conjugates able to inhibit gene expression in resistant cell lines, Mol. Pharmacol. 2008 May;73(5):1568-77.
• 2008
  Koster DA, Czerwinski F, Halby L, Crut A, Vekhoff P, Palle K, Arimondo PB, Dekker NH, Single-molecule observations of topotecan-mediated TopIB activity at a unique DNA sequence, Nucleic Acids Res. 2008 Apr;36(7):2301-10.
• 2007
  Kamashev D, Balandina A, Mazur AK, Arimondo PB, Rouviere-Yaniv J, HU binds and folds single-stranded DNA, Nucleic Acids Res. 2008 Feb;36(3):1026-36.
• 2007
  Rossignol JM, Jacquet M, Arimondo PB, “DNA, more than just a ladder”. A tribute to Michel Duguet (1943-2005), Biochimie 2007 Apr;89(4):423-6.
• 2007
  Nöllmann M, Crisona NJ, Arimondo PB, Thirty years of Escherichia coli DNA gyrase: from in vivo function to single-molecule mechanism, Biochimie 2007 Apr;89(4):490-9.
• 2006
  Belotserkovskii BP, Arimondo PB, Cozzarelli NR, Topoisomerase action on short DNA duplexes reveals requirements for gate and transfer DNA segments, J. Biol. Chem. 2006 Sep;281(35):25407-15.
• 2006
  Duca M, Guianvarc'h D, Oussedik K, Halby L, Garbesi A, Dauzonne D, Monneret C, Osheroff N, Giovannangeli C, Arimondo PB, Molecular basis of the targeting of topoisomerase II-mediated DNA cleavage by VP16 derivatives conjugated to triplex-forming oligonucleotides, Nucleic Acids Res. 2006;34(6):1900-11.
• 2006
  Guillaumel J, Léonce S, Pierré A, Renard P, Pfeiffer B, Arimondo PB, Monneret C, Synthesis and biological activity of 6H-isoindolo[2,1-a]indol-6-ones, analogues of batracylin, and related compounds, Eur J Med Chem 2006 Mar;41(3):379-86.
• 2006
  Arimondo PB, Thomas CJ, Oussedik K, Baldeyrou B, Mahieu C, Halby L, Guianvarc'h D, Lansiaux A, Hecht SM, Bailly C, Giovannangeli C, Exploring the cellular activity of camptothecin-triple-helix-forming oligonucleotide conjugates, Mol. Cell. Biol. 2006 Jan;26(1):324-33.
• 2005
  Duca M, Oussedik K, Ceccaldi A, Halby L, Guianvarc'h D, Dauzonne D, Monneret C, Sun JS, Arimondo PB, Triple helix-forming oligonucleotides conjugated to new inhibitors of topoisomerase II: synthesis and binding properties, Bioconjug. Chem. 2005 Jul-Aug;16(4):873-84.
• 2005
  Arimondo PB, Laco GS, Thomas CJ, Halby L, Pez D, Schmitt P, Boutorine A, Garestier T, Pommier Y, Hecht SM, Sun JS, Bailly C, Activation of camptothecin derivatives by conjugation to triple helix-forming oligonucleotides, Biochemistry 2005 Mar;44(11):4171-80.
• 2005
  Duca M, Arimondo PB, Léonce S, Pierré A, Pfeiffer B, Monneret C, Dauzonne D, Novel carbamate derivatives of 4-beta-amino-4′-O-demethyl-4-desoxypodophyllotoxin as inhibitors of topoisomerase II: synthesis and biological evaluation, Org. Biomol. Chem. 2005 Mar;3(6):1074-80.
• 2005
  Duca M, Guianvarc'h D, Meresse P, Bertounesque E, Dauzonne D, Kraus-Berthier L, Thirot S, Léonce S, Pierré A, Pfeiffer B, Renard P, Arimondo PB, Monneret C, Synthesis and biological study of a new series of 4′-demethylepipodophyllotoxin derivatives, J. Med. Chem. 2005 Jan;48(2):593-603.
• 2004
  Antony S, Arimondo PB, Sun JS, Pommier Y, Position- and orientation-specific enhancement of topoisomerase I cleavage complexes by triplex DNA structures, Nucleic Acids Res. 2004;32(17):5163-73.
• 2004
  Guianvarc'h D, Duca M, Boukarim C, Kraus-Berthier L, Léonce S, Pierré A, Pfeiffer B, Renard P, Arimondo PB, Monneret C, Dauzonne D, Synthesis and biological activity of sulfonamide derivatives of epipodophyllotoxin, J. Med. Chem. 2004 Apr;47(9):2365-74.
• 2004
  Shim YH, Arimondo PB, Laigle A, Garbesi A, Lavielle S, Relative DNA binding affinity of helix 3 homeodomain analogues, major groove binders, can be rapidly screened by displacement of prebound ethidium bromide. A comparative study, Org. Biomol. Chem. 2004 Mar;2(6):915-21.
• 2003
  Arimondo PB, Angenault S, Halby L, Boutorine A, Schmidt F, Monneret C, Garestier T, Sun JS, Bailly C, Hélène C, Spatial organization of topoisomerase I-mediated DNA cleavage induced by camptothecin-oligonucleotide conjugates, Nucleic Acids Res. 2003 Jul;31(14):4031-40.
• 2003
  Guillaumel J, Léonce S, Pierré A, Renard P, Pfeiffer B, Peruchon L, Arimondo PB, Monneret C, Synthesis and antiproliferative activity of basic ethers of 1,2-dihydropyrrolo[1,2-a]indole, 6H-isoindolo[2,1-a]indole, and 6H-benz[5,6]isoindolo[2,1-a]indole, Oncol. Res. 2003;13(12):537-49.
• 2003
  Vinogradov S, Roig V, Sergueeva Z, Nguyen CH, Arimondo P, Thuong NT, Bisagni E, Sun JS, Hélène C, Asseline U, Synthesis and binding properties of oligo-2′-deoxyribonucleotides conjugated with triple-helix-specific intercalators: benzo[e] and benzo[g] pyridoindoles, Bioconjug. Chem. 2003 Jan-Feb;14(1):120-35.
• 2002
  Alberti P, Arimondo PB, Mergny JL, Garestier T, Hélène C, Sun JS, A directional nucleation-zipping mechanism for triple helix formation, Nucleic Acids Res. 2002 Dec;30(24):5407-15.
• 2002
  Roulland E, Magiatis P, Arimondo P, Bertounesque E, Monneret C, Hemi-synthesis and biological activity of new analogues of podophyllotoxin, Bioorg. Med. Chem. 2002 Nov;10(11):3463-71.
• 2002
  Mills M, Lacroix L, Arimondo PB, Leroy JL, François JC, Klump H, Mergny JL, Unusual DNA conformations: implications for telomeres, Curr Med Chem Anticancer Agents 2002 Sep;2(5):627-44.
• 2002
  Mills M, Arimondo PB, Lacroix L, Garestier T, Klump H, Mergny JL, Chemical modification of the third strand: differential effects on purine and pyrimidine triple helix formation, Biochemistry 2002 Jan;41(1):357-66.
• 2001
  Arimondo PB, Boutorine A, Baldeyrou B, Bailly C, Kuwahara M, Hecht SM, Sun JS, Garestier T, Hélène C, Design and optimization of camptothecin conjugates of triple helix-forming oligonucleotides for sequence-specific DNA cleavage by topoisomerase I, J. Biol. Chem. 2002 Feb;277(5):3132-40.
• 2001
  Arimondo PB, Hélène C, Design of new anti-cancer agents based on topoisomerase poisons targeted to specific DNA sequences, Curr Med Chem Anticancer Agents 2001 Nov;1(3):219-35.
• 2001
  Arimondo PB, Baldeyrou B, Laine W, Bal C, Alphonse FA, Routier S, Coudert G, Mérour JY, Colson P, Houssier C, Bailly C, DNA interaction and cytotoxicity of a new series of indolo[2,3-b]quinoxaline and pyridopyrazino[2,3-b]indole derivatives, Chem. Biol. Interact. 2001 Oct;138(1):59-75.
• 2001
  Arimondo PB, Bailly C, Boutorine AS, Moreau P, Prudhomme M, Sun JS, Garestier T, Hélène C, Triple helix-forming oligonucleotides conjugated to indolocarbazole poisons direct topoisomerase I-mediated DNA cleavage to a specific site, Bioconjug. Chem. 2001 Jul-Aug;12(4):501-9.
• 2001
  Mergny JL, Lacroix L, Teulade-Fichou MP, Hounsou C, Guittat L, Hoarau M, Arimondo PB, Vigneron JP, Lehn JM, Riou JF, Garestier T, Hélène C, Telomerase inhibitors based on quadruplex ligands selected by a fluorescence assay, Proc. Natl. Acad. Sci. U.S.A. 2001 Mar;98(6):3062-7.
• 2001
  Koeppel F, Riou JF, Laoui A, Mailliet P, Arimondo PB, Labit D, Petitgenet O, Hélène C, Mergny JL, Ethidium derivatives bind to G-quartets, inhibit telomerase and act as fluorescent probes for quadruplexes, Nucleic Acids Res. 2001 Mar;29(5):1087-96.
• 2001
  Arimondo PB, Garestier T, Hélène C, Sun JS, Detection of competing DNA structures by thermal gradient gel electrophoresis: from self-association to triple helix formation by (G,A)-containing oligonucleotides, Nucleic Acids Res. 2001 Feb;29(4):E15.
• 2001
  Arimondo PB, Bailly C, Boutorine AS, Ryabinin VA, Syniakov AN, Sun JS, Garestier T, Hélène C, Directing topoisomerase I mediated DNA cleavage to specific sites by camptothecin tethered to minor- and major-groove ligands, Angew. Chem. Int. Ed. Engl. 2001;40(16):3045-8.
• 2000
  Arimondo PB, Riou JF, Mergny JL, Tazi J, Sun JS, Garestier T, Hélène C, Interaction of human DNA topoisomerase I with G-quartet structures, Nucleic Acids Res. 2000 Dec;28(24):4832-8.
• 2000
  Arimondo P, Boukarim C, Bailly C, Dauzonne D, Monneret C, Design of two etoposide-amsacrine conjugates: topoisomerase II and tubuline polymerization inhibition and relation to cytotoxicity, Anticancer Drug Des. 2000 Dec;15(6):413-21.
• 2000
  Arimondo PB, Gelus N, Hamy F, Payet D, Travers A, Bailly C, The chromosomal protein HMG-D binds to the TAR and RBE RNA of HIV-1, FEBS Lett. 2000 Nov;485(1):47-52.
• 2000
  Arimondo P, Bailly C, Boutorine A, Asseline U, Sun JS, Garestier T, Hélène C, Linkage of a triple helix-forming oligonucleotide to amsacrine-4-carboxamide derivatives modulates the sequence-selectivity of topoisomerase II-mediated DNA cleavage, Nucleosides Nucleotides Nucleic Acids 2000 Aug;19(8):1205-18.
• 2000
  Lacroix L, Arimondo PB, Takasugi M, Hélène C, Mergny JL, Pyrimidine morpholino oligonucleotides form a stable triple helix in the absence of magnesium ions, Biochem. Biophys. Res. Commun. 2000 Apr;270(2):363-9.
• 2000
  Arimondo PB, Moreau P, Boutorine A, Bailly C, Prudhomme M, Sun JS, Garestier T, Hélène C, Recognition and cleavage of DNA by rebeccamycin- or benzopyridoquinoxaline conjugated of triple helix-forming oligonucleotides, Bioorg. Med. Chem. 2000 Apr;8(4):777-84.
• 1999
  Mills M, Arimondo PB, Lacroix L, Garestier T, Hélène C, Klump H, Mergny JL, Energetics of strand-displacement reactions in triple helices: a spectroscopic study, J. Mol. Biol. 1999 Sep;291(5):1035-54.
• 1999
  Arimondo PB, Bailly C, Boutorine A, Sun JS, Garestier T, Hélène C, Targeting topoisomerase I cleavage to specific sequences of DNA by triple helix-forming oligonucleotide conjugates. A comparison between a rebeccamycin derivative and camptothecin, C. R. Acad. Sci. III, Sci. Vie 1999 Sep;322(9):785-90.
• 1998
  Arimondo PB, Barcelo F, Sun JS, Maurizot JC, Garestier T, Hélène C, Triple helix formation by (G,A)-containing oligonucleotides: asymmetric sequence effect, Biochemistry 1998 Nov;37(47):16627-35.
• 1998
  Arimondo PB, Calderazzo F, Hiemeyer R, Maichle-Mössmer C, Marchetti F, Pampaloni G, Strähle J, Synthesis and Crystal Structure of a Self-Assembled, Octanuclear Oxo-Tantalum(V) Derivative Containing the First Example of a Transition Metal M(8)(&mgr;-O)(12) Cage, Inorg Chem 1998 Oct;37(21):5507-5511.