Our research on Bordetella covers the population biology and epidemiology of various Bordetella species, including B. pertussis, the major agent of whooping cough; vaccine improvements; and the impact of vaccination on population evolution. Current research lines include:
(i) Diversity, evolution and transmission of Bordetellae using genomics, transcriptomics and proteomics
(ii) Vaccine-induced and pathogen-induced immunity
(iii) Identification and functional analysis of bacterial determinants of malignant pertussis (most severe infections)
Our projects on Bordetella leverage and reinforce the resources and expertise of the French National Reference Center for Whooping cough and other Bordetella infections (web pages in French).