(EN) Induction and analysis of Neutrophil Extracellular Trap (NET) formation in microfluidic droplets (Master 2)
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Use of microfluidic approaches to study Neutrophil Extracellular Trap formation
Netosis consists of the ejection of DNA filaments by activated neutrophils resulting in extracellular DNA (Neutrophil Extracellular Traps, NETs). This DNA has antimicrobial properties but is also toxic to surrounding tissues. NETs have recently […]
Role of platelets and their interactions in allergic diseases
Role of platelets and their interactions in allergic diseases that aims at understanding how platelets induce/promote/regulate antibody-induced allergic diseases, their interaction partners (myeloid cells, endothelium) and their dynamics.
Clinical and pathological consequences of human anti-drug antibodies (NASA study)
Clinical and pathological consequences of human anti-drug antibodies (NASA study) that aims at demonstrating in the clinic that neutrophils are activated by antibody-curare complexes and involved in curare-induced anaphylaxis (allergic shock) in humans, and […]
USE OF ANTl-FcyRI AND/OR ANTl-FcyRllA ANTIBODIES FOR TREATING ARTHRITIS, INFLAMMATION, THROMBOCYTOPENIA AND ALLERGIC SHOCK
The present invention relates to the prevention and/or treatment of arthritic, inflammatory and/or allergic reactions as well as thrombocytopenia, by blocking the human receptors FcyRI and FcyRIIA. It is disclosed a mouse monoclonal antibody […]
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2020Mouse Models and Tools for the in vivo Study of Neutrophils., Front Immunol. 2020 Jan 21;10:3130..
2019Expression, Role, and Regulation of Neutrophil Fcγ Receptors., Front Immunol. 2019 Aug 27;10:1958. Review..
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