Timeline

Friederike Jönsson

Group Leader

24 Oct 2024

project

Characterization and functional consequences of anti-Caspr2 antibodies in autoimmune encephalitis patients

03 Oct 2024

publication

Humoral signatures of Caspr2-antibody spectrum disorder track with clinical phenotypes and outcomes.

11 Sep 2024

publication

Rocuronium-specific antibodies drive perioperative anaphylaxis but can also function as reversal agents in preclinical models.

31 Jul 2024

publication

Dual neutralization of influenza virus hemagglutinin and neuraminidase by a bispecific antibody leads to improved antiviral activity

01 Feb 2024

publication

Standardized high-dimensional spectral cytometry protocol and panels for whole blood immune phenotyping in clinical and translational studies.

15 Dec 2023

project

Étude du phénomène de libération par les polynucléaires neutrophiles de fibres d’ADN et de protéines : NETOSIS

25 Aug 2023

publication

A human immune system (HIS) mouse model that dissociates roles for mouse and human FcR+ cells during antibody-mediated immune responses.

06 Apr 2023

publication

Conditional neutrophil depletion challenges their contribution to mouse models of anaphylaxis.

01 Jan 2023

publication

Isolation methods determine human neutrophil responses after stimulation.

17 Aug 2022

project

Induction and analysis of Neutrophil Extracellular Trap (NET) formation in microfluidic droplets (Master 2)

02 Jun 2022

publication

Current research and unmet needs in allergy and immunology in Germany: report presented by the DGfI and DGAKI task force Allergy & Immunology

01 Jun 2022

publication

The role of neutrophils in antibody-driven autoimmune cytopenias.

08 Feb 2022

publication

Specificity of mouse and human Fcgamma receptors and their polymorphic variants for IgG subclasses of different species.

14 Sep 2021

publication

Platelet FcγRIIA-induced serotonin release exacerbates the severity of Transfusion-Related Acute Lung Injury in mice

03 Sep 2021

publication

Neutrophil-specific gain-of-function mutations in Nlrp3 promote development of cryopyrin-associated periodic syndrome

22 Jan 2021

publication

The role of IgG subclasses and platelets in experimental anaphylaxis.

06 Mar 2020

publication

Cofilin1-driven Actin Dynamics Controls Migration of Thymocytes and Is Essential for Positive Selection in the Thymus

02 Mar 2020

publication

Human IgA binds a diverse array of commensal bacteria

21 Jan 2020

publication

Mouse Models and Tools for the in vivo Study of Neutrophils.

27 Aug 2019

publication

Expression, Role, and Regulation of Neutrophil Fcγ Receptors.

31 Jul 2019

event

Department of Immunology seminar: Betty Diamond, B cell tolerance and plasma cell differentiation in SLE.

10 Jul 2019

publication

An IgG-induced neutrophil activation pathway contributes to human drug-induced anaphylaxis

16 Oct 2018

project

Use of microfluidic approaches to study Neutrophil Extracellular Trap formation

14 Sep 2018

team

Group: Allergy and Autoimmunity

19 Apr 2018

publication

MUB40 Binds to Lactoferrin and Stands as a Specific Neutrophil Marker.

13 Apr 2018

publication

Platelets expressing IgG receptor FcγRIIA/CD32A determine the severity of experimental anaphylaxis.

20 Oct 2017

publication

Low end-tidal CO2 as a real-time severity marker of intra-anaesthetic acute hypersensitivity reactions.

17 Feb 2017

publication

Neutrophil myeloperoxidase diminishes the toxic effects and mortality induced by lipopolysaccharide

20 Dec 2016

publication

Trans-inhibition of activation and proliferation signals by Fc receptors in mast cells and basophils.

10 Oct 2016

publication

In vivo effector functions of high-affinity mouse IgG receptor FcγRI in disease and therapy models.

26 Sep 2016

event

2015-2016 Institut Pasteur PhD Graduation Ceremony

24 Aug 2016

publication

Mechanisms of anaphylaxis in human low-affinity IgG receptor locus knock-in mice.

21 Jul 2016

event

Andres Hidalgo Alonso seminar

06 Jul 2016

publication

Mucosal mast cells are indispensable for the timely termination of Strongyloides ratti infection.fr

26 Apr 2016

publication

IgG subclasses determine pathways of anaphylaxis in mice

26 Oct 2015

publication

Mouse and human FcR effector functions.

01 Sep 2015

patent

USE OF ANTl-FcyRI AND/OR ANTl-FcyRllA ANTIBODIES FOR TREATING ARTHRITIS, INFLAMMATION, THROMBOCYTOPENIA AND ALLERGIC SHOCK

27 May 2015

publication

Shaping mycolactone for therapeutic use against inflammatory disorders.

11 May 2015

team

Antibodies in Therapy and Pathology

25 Jul 2014

publication

Shifting FcγRIIA-ITAM from activation to inhibitory configuration ameliorates arthritis

30 May 2014

publication

Contribution of Human FcγRs to Disease with Evidence from Human Polymorphisms and Transgenic Animal Studies

14 Feb 2014

publication

Severe protein aggregate myopathy in a knockout mouse model points to an essential role of cofilin2 in sarcomeric actin exchange and muscle maintenance

26 Aug 2013

publication

Neutrophils mediate antibody-induced antitumor effects in mice

26 Mar 2013

publication

Neutrophils in local and systemic antibody-dependent inflammatory and anaphylactic reactions

04 Jan 2013

publication

The high-affinity human IgG receptor FcγRI (CD64) promotes IgG-mediated inflammation, anaphylaxis, and antitumor immunotherapy

01 Sep 2012

publication

A hypomorphic mutation in the Gfi1 transcriptional repressor results in a novel form of neutropenia

20 Aug 2012

publication

Fcγ receptors inhibit mouse and human basophil activation

27 Apr 2012

publication

Immunological responses and actin dynamics in macrophages are controlled by N-cofilin but are independent from ADF

20 Feb 2012

publication

Mast cells and company

02 Dec 2011

publication

Human FcγRIIA induces anaphylactic and allergic reactions

21 Oct 2011

publication

[An unexpected role for neutrophils in anaphylaxis]

23 Mar 2011

publication

Mouse and human neutrophils induce anaphylaxis

19 Jan 2011

publication

Cutting Edge: The murine high-affinity IgG receptor FcγRIV is sufficient for autoantibody-induced arthritis

15 Feb 2009

publication

A little guide for advanced search:

Characterization and functional consequences of anti-Caspr2 antibodies in autoimmune encephalitis patients

Humoral signatures of Caspr2-antibody spectrum disorder track with clinical phenotypes and outcomes.

Rocuronium-specific antibodies drive perioperative anaphylaxis but can also function as reversal agents in preclinical models.

Dual neutralization of influenza virus hemagglutinin and neuraminidase by a bispecific antibody leads to improved antiviral activity

Standardized high-dimensional spectral cytometry protocol and panels for whole blood immune phenotyping in clinical and translational studies.

Étude du phénomène de libération par les polynucléaires neutrophiles de fibres d’ADN et de protéines : NETOSIS

A human immune system (HIS) mouse model that dissociates roles for mouse and human FcR+ cells during antibody-mediated immune responses.

Conditional neutrophil depletion challenges their contribution to mouse models of anaphylaxis.

Isolation methods determine human neutrophil responses after stimulation.

Induction and analysis of Neutrophil Extracellular Trap (NET) formation in microfluidic droplets (Master 2)

Current research and unmet needs in allergy and immunology in Germany: report presented by the DGfI and DGAKI task force Allergy & Immunology

The role of neutrophils in antibody-driven autoimmune cytopenias.

Specificity of mouse and human Fcgamma receptors and their polymorphic variants for IgG subclasses of different species.

Platelet FcγRIIA-induced serotonin release exacerbates the severity of Transfusion-Related Acute Lung Injury in mice

Neutrophil-specific gain-of-function mutations in Nlrp3 promote development of cryopyrin-associated periodic syndrome

The role of IgG subclasses and platelets in experimental anaphylaxis.

Cofilin1-driven Actin Dynamics Controls Migration of Thymocytes and Is Essential for Positive Selection in the Thymus

Human IgA binds a diverse array of commensal bacteria

Mouse Models and Tools for the in vivo Study of Neutrophils.

Expression, Role, and Regulation of Neutrophil Fcγ Receptors.

Department of Immunology seminar: Betty Diamond, B cell tolerance and plasma cell differentiation in SLE.

An IgG-induced neutrophil activation pathway contributes to human drug-induced anaphylaxis

Use of microfluidic approaches to study Neutrophil Extracellular Trap formation

Group: Allergy and Autoimmunity

MUB40 Binds to Lactoferrin and Stands as a Specific Neutrophil Marker.

Platelets expressing IgG receptor FcγRIIA/CD32A determine the severity of experimental anaphylaxis.

Low end-tidal CO2 as a real-time severity marker of intra-anaesthetic acute hypersensitivity reactions.

Neutrophil myeloperoxidase diminishes the toxic effects and mortality induced by lipopolysaccharide

Trans-inhibition of activation and proliferation signals by Fc receptors in mast cells and basophils.

In vivo effector functions of high-affinity mouse IgG receptor FcγRI in disease and therapy models.

2015-2016 Institut Pasteur PhD Graduation Ceremony

Mechanisms of anaphylaxis in human low-affinity IgG receptor locus knock-in mice.

Andres Hidalgo Alonso seminar

Mucosal mast cells are indispensable for the timely termination of Strongyloides ratti infection.fr

IgG subclasses determine pathways of anaphylaxis in mice

Mouse and human FcR effector functions.

USE OF ANTl-FcyRI AND/OR ANTl-FcyRllA ANTIBODIES FOR TREATING ARTHRITIS, INFLAMMATION, THROMBOCYTOPENIA AND ALLERGIC SHOCK

Shaping mycolactone for therapeutic use against inflammatory disorders.

Antibodies in Therapy and Pathology

Shifting FcγRIIA-ITAM from activation to inhibitory configuration ameliorates arthritis

Contribution of Human FcγRs to Disease with Evidence from Human Polymorphisms and Transgenic Animal Studies

Severe protein aggregate myopathy in a knockout mouse model points to an essential role of cofilin2 in sarcomeric actin exchange and muscle maintenance

Neutrophils mediate antibody-induced antitumor effects in mice

Neutrophils in local and systemic antibody-dependent inflammatory and anaphylactic reactions

The high-affinity human IgG receptor FcγRI (CD64) promotes IgG-mediated inflammation, anaphylaxis, and antitumor immunotherapy

A hypomorphic mutation in the Gfi1 transcriptional repressor results in a novel form of neutropenia

Fcγ receptors inhibit mouse and human basophil activation

Immunological responses and actin dynamics in macrophages are controlled by N-cofilin but are independent from ADF

Mast cells and company

Human FcγRIIA induces anaphylactic and allergic reactions

[An unexpected role for neutrophils in anaphylaxis]

Mouse and human neutrophils induce anaphylaxis

Cutting Edge: The murine high-affinity IgG receptor FcγRIV is sufficient for autoantibody-induced arthritis

Human basophils express the glycosylphosphatidylinositol-anchored low-affinity IgG receptor FcgammaRIIIB (CD16B)