LabEx IBEID – Integrative Biology of Emerging Infectious Diseases
Presentation Le but du projet Biologie Intégrative des Maladies Infectieuses Emergentes (IBEID), coordonné par les professeurs Philippe Sansonetti et Pascale Cossart, est de développer une structure pour anticiper et lutter contre les maladies […]
INDUCE: INciDence and conseqUenCes of sEpsis in France
As recently acknowledged by the WHO, sepsis is the number one killer from infectious diseases, mostly bacterial infections, and as such has emerged as a major public health priority. Global estimates ascribe to sepsis […]
BactHub: Antibiotic exposure and antibiotic-resistant bacteremia in the community
Antibiotic resistance rates are increasing worldwide, especially for Gram-negative bacteria, potentially responsible for difficult-to-treat infections and therapeutic failures. While the high prevalence of resistance in hospitals is a long-lived concern, resistance is now spreading […]
Project MOD-COV (Modelling of the hOspital Dissemination of SARS-CoV-2) In the context of SARS-CoV-2 pandemic, healthcare institutions are confronted to major challenges. First the community spread is leading to a large demand in available […]
I-Share is an Internet-based Students HeAlth Research Enterprise. It is an entirely new, prospective cohort of 30,000 students registered in the first years of study at the Universities of Bordeaux and Versailles-Saint-Quentin during five years and followed […]
Modelling Infection Spread in Hospitals
Despite advances in modern biology and medicine, antibiotic-resistant bacteria (ARB) have spread in the community and in hospitals over the last decades, becoming a major public health problem. Mathematical modeling and computer simulations are […]
MIBAC: Antibiotic use in the community
Since 2002 a centralized storage of therapeutic or preventive medications of bacterial infections in the community (MIBAC) has been initiated. Reimbursements for all systemic antibiotics (class J01 of the Anatomical Therapeutic classification), as well […]
PHIBRA: Bacterial resistance to antibiotics
Bacterial resistance to antibiotics has become a major public health issue. A recent report, delivered to the Minister of Health in September 2015, pointed out 158,000 cases of infections by antibiotic-resistant bacteria annually in […]
I-BIRD: Individual Based Investigation of Resistance Dissemination
The i-Bird program was devoted to explore the ability of MRSA and ER3GC to disseminate within hospital clinical departments. This program involved tracing the clonal dissemination of MRSA and ER3GC among hospitalized patients and […]
Ad hoc epidemiological investigations
Current research investigations Antibiotic use and Staphylococcus aureus resistant to antibiotics, ASAR This study is a prospective pharmacoepidemiological investigation involving the establishment of a cohort of hospitalized individuals not initially colonized with S. aureus. […]
Current and future research programs
Challenges in understanding the determinants of anti-infection agent escape New antibiotic components are being developed and, provided the necessary investments are made, new antibiotics may therefore become available within the next few years. […]
Main achievements over the last 5 years
Determinants of the spread and competitiveness of multiresistant bacteria In 2000, we investigated whether pneumococcal resistance to penicillin G in a child population could be controlled by modifying the use of antibiotics in […]
2021Severe bacterial neonatal infections in Madagascar, Senegal, and Cambodia: A multicentric community-based cohort study., PLoS Med 2021 Sep; 18(9): e1003681.
2021Antibiotic prescriptions and risk factors for antimicrobial resistance in patients hospitalized with urinary tract infection: a matched case-control study using the French health insurance database (SNDS), BMC Infect Dis 2021 Jun; 21(1): 571.
2021Outpatient antibiotic use attributable to viral acute lower respiratory tract infections during the cold season in France, 2010-2017, Int J Antimicrob Agents 2021 Jun; 57(6): 106339.
2021Costs and Outcomes of 1-year post-discharge care trajectories of patients admitted with infection due to antibiotic-resistant bacteria, J Infect 2021 03; 82(3): 339-345.
2020Optimizing COVID-19 surveillance in long-term care facilities: a modelling study., BMC Med 2020 12; 18(1): 386.
2019Association of Pneumococcal Conjugate Vaccine Coverage With Pneumococcal Meningitis: An Analysis of French Administrative Areas, 2001-2016, Am. J. Epidemiol. 2019 Aug;188(8):1466-1474.
2019Transmission Routes of Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae in a Neonatology Ward in Madagascar, Am. J. Trop. Med. Hyg. 2019 06;100(6):1355-1362.
2019A Payer Perspective of the Hospital Inpatient Additional Care Costs of Antimicrobial Resistance in France: A Matched Case-Control Study, Appl Health Econ Health Policy 2019 Jun;17(3):381-389.
2019Close proximity interactions support transmission of ESBL-K. pneumoniae but not ESBL-E. coli in healthcare settings, PLoS Comput. Biol. 2019 05;15(5):e1006496.
2019Host contact dynamics shapes richness and dominance of pathogen strains, PLoS Comput. Biol. 2019 May;15(5):e1006530.
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