Although competitive interactions between bacteria (bacterial interference), are likely to represent a key aspect of many infectious processes, the nature of these interactions within mixed biofilm communities is poorly understood. We use in vitro biofilm models […]
Specific metabolic changes occurring during biofilm formation were hypothesized to lead to the production of biofilm-associated molecules and biofilm-specific functions. The identification of biofilm-specific metabolites could reveal new aspects of biofilm biology, and lead to novel strategies […]
Biofilm Tolerance to Antibiotics
One of the of the hallmarks of biofilm physiology is its tolerance to a high level of antimicrobials. We are currently investigating the molecular mechanisms that lead to this transient ability to withstand antimicrobial treatments. […]
Biofilm Volatile Compounds
Bacteria produce and release into their headspace a wide variety of volatile secondary metabolites. However, While detection and quantification of these volatiles as attractive or repellent odors and aromas are of great interest in food and cosmetic […]
2017Biofilm microenvironment induces a widespread adaptive amino-acid fermentation pathway conferring strong fitness advantage in Escherichia coli, PLoS Genetics, May 19;13(5):e1006800.
2015Airborne bacterial interactions: Functions out of thin air?, Front. Microbiol. Dec. 2015;6:1476..
2014Aerial exposure to the bacterial volatile compound trimethylamine modifies antibiotic resistance of physically separated bacteria by raising culture medium pH, MBio 2014;5(1):e00944-13.
2004Haemophore-mediated signalling in Serratia marcescens: a new mode of regulation for an extra cytoplasmic function (ECF) sigma factor involved in haem acquisition, Mol Microbiol. 2004 Aug;53(4):1267-77.
2001Identification and characterization of the hemophore-dependent heme acquisition system of Yersinia pestis, Infect Immun. 2001 Nov;69(11):6707-17.