Christiane Bouchier

Our main objective is to increase the knowledge regarding the human virome during homeostasis and diseases. We mainly focus on: immunocompromised patients, where new pathogens and new associations between known pathogens and diseases at found at higher frequency than […]

Cholera is thought by many to be a disease of the Victorian era. However, Yemen has recently experienced one of the largest ever cholera epidemics. The first cases were declared in September 2016, and […]

Little is known about the emergence and spread of the first antibiotic-resistant populations. It is believed, for example, that the very common penicillinase gene, blaTEM-1, discovered for the first time in E. coli in Greece […]

This project intends to share expertise, developments, equipement and bioinformatics tools to apply Oxford Nanopore Technology sequencing to the detection, diagnostic and characterization of pathogens of public health importance. It corresponds to a collaboration […]

The agent of epidemic dysentery, the bacterium Shigella dysenteriae type 1, was isolated in Japan in 1897 by Dr Kyoshi Shiga during a massive epidemic of bloody diarrhea that caused 20,000 deaths over a […]

Non-segmented negative strand RNA viruses are characterized by an intrinsic genome instability, the result of an error-prone RNA dependant RNA polymerase. To date, most viral populations have been characterized by their consensus genome sequences. […]

Sequana is a Python framework designed to provide pipelines to analyse Next Generation Sequencing data sets. Sequana provides tools to access the sequence quality but also post-processing analysis such as depth of coverage or […]