Timeline

Jean-Pierre Changeux
Honorary President of the Departement
24 Sep 2021
news

Jean-Pierre Changeux selected as a Clarivate Citation Laureate

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29 Jul 2021
news

Ivermectin alleviates COVID-19 symptoms in an animal model

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26 Jul 2021
team

Allosteric modulation of pentameric receptor channels and relevance to Covid 19

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25 Jun 2021
publication

Attenuation of clinical and immunological outcomes during SARS-CoV-2 infection by ivermectin.

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01 Jun 2021
publication

Ivermectin as a potential treatment for COVID-19?

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31 Mar 2021
publication

A Connectomic Hypothesis for the Hominization of the Brain.

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19 Jan 2021
publication

The natural axis of transmitter receptor distribution in the human cerebral cortex.

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01 Aug 2020
publication

Do Nicotinic Receptors Modulate High-Order Cognitive Processing?

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08 Jul 2020
publication

Golden Anniversary of the Nicotinic Receptor.

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05 Jun 2020
publication

A nicotinic hypothesis for Covid-19 with preventive and therapeutic implications.

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01 Jun 2020
publication

The Glycine Receptor Allosteric Ligands Library (GRALL).

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03 Apr 2020
publication

Discovery of the First Neurotransmitter Receptor: The Acetylcholine Nicotinic Receptor.

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04 Mar 2020
publication

Conscious Processing and the Global Neuronal Workspace Hypothesis.

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04 Feb 2020
publication

A strategy for designing allosteric modulators of transcription factor dimerization.

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01 Jan 2020
publication

The Molecular Organization of Self-awareness: Paralimbic Dopamine-GABA Interaction.

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07 Feb 2019
publication

Allostery in Its Many Disguises: From Theory to Applications.

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19 Nov 2018
publication

Drug Addiction: From Neuroscience to Ethics

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19 Jun 2018
publication

The nicotinic acetylcholine receptor: a typical ‘allosteric machine’

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19 Apr 2018
project

The use of computational methods to design drugs – Human Brain Project Specific Grant Agreement 1

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01 Feb 2018
publication

Structural Identification of the Nicotinic Receptor Ion Channel

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25 Oct 2017
publication

Un-gating and allosteric modulation of a pentameric ligand-gated ion channel captured by molecular dynamics

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01 Sep 2017
publication

Allosteric modulation as a unifying mechanism for receptor function and regulation

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25 Jul 2017
publication

Response by the authors

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01 Feb 2017
publication

Climbing Brain Levels of Organisation from Genes to Consciousness

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20 Dec 2016
publication

Nicotinic receptors in mouse prefrontal cortex modulate ultraslow fluctuations related to conscious processing.

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23 Dec 2013
publication

Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation

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06 Jun 2012
publication

Structure and pharmacology of pentameric receptor channels: from bacteria to brain

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20 Jan 2011
publication

X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel

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22 Mar 2010
publication

One-microsecond molecular dynamics simulation of channel gating in a nicotinic receptor homologue

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01 Apr 2005
publication

Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism

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01 Jan 1989
publication

An evaluation of the Coulter VCS differential counter.

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