Timeline

Jean-Pierre Changeux
Honorary President of the Departement
07 Feb 2019
publication

Allostery in Its Many Disguises: From Theory to Applications

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19 Nov 2018
publication

Drug Addiction: From Neuroscience to Ethics

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19 Jun 2018
publication

The nicotinic acetylcholine receptor: a typical ‘allosteric machine’

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19 Apr 2018
project

The use of computational methods to design drugs – Human Brain Project Specific Grant Agreement 1

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01 Feb 2018
publication

Structural Identification of the Nicotinic Receptor Ion Channel

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25 Oct 2017
publication

Un-gating and allosteric modulation of a pentameric ligand-gated ion channel captured by molecular dynamics

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01 Sep 2017
publication

Allosteric modulation as a unifying mechanism for receptor function and regulation

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25 Jul 2017
publication

Response by the authors

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01 Feb 2017
publication

Climbing Brain Levels of Organisation from Genes to Consciousness

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02 Dec 2016
publication

Nicotinic receptors in mouse prefrontal cortex modulate ultraslow fluctuations related to conscious processing.

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23 Dec 2013
publication

Crystal structures of a pentameric ligand-gated ion channel provide a mechanism for activation

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06 Jun 2012
publication

Structure and pharmacology of pentameric receptor channels: from bacteria to brain

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20 Jan 2011
publication

X-ray structures of general anaesthetics bound to a pentameric ligand-gated ion channel

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22 Mar 2010
publication

One-microsecond molecular dynamics simulation of channel gating in a nicotinic receptor homologue

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01 Apr 2005
publication

Normal mode analysis suggests a quaternary twist model for the nicotinic receptor gating mechanism

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