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© Research
Publication : Frontiers in systems neuroscience

The Molecular Organization of Self-awareness: Paralimbic Dopamine-GABA Interaction.

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Frontiers in systems neuroscience - 01 Jan 2020

Lou HC, Rømer Thomsen K, Changeux JP,

Link to Pubmed [PMID] – 32047425

Link to DOI – 10.3389/fnsys.2020.00003

Front Syst Neurosci 2020 ; 14(): 3

The electrophysiology of the paralimbic network (“default mode”) for self-awareness has drawn much attention in the past couple of decades. In contrast, knowledge of the molecular organization of conscious experience has only lately come into focus. We here review newer data on dopaminergic control of awareness in humans, particularly in self-awareness. These results implicate mainly dopaminergic neurotransmission and the control of GABAergic function directly in the paralimbic network. The findings are important for understanding addiction, developmental disorders, and dysfunctional consciousness.

https://pubmed.ncbi.nlm.nih.gov/32047425