Timeline

Miria Ricchetti
Group Leader
06 Dec 2019
publication
CSB promoter downregulation via histone H3 hypoacetylation is an early determinant of replicative senescence
Read more25 Mar 2019
event
Developmental and Stem Cell Biology Department seminar by: Professor Juan-Carlos Izpisua Belmonte, Salk Institute for Biological Studies, La Jolla California
Read more09 Nov 2018
publication
Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells
Read more07 Sep 2018
event
Extra seminar by Francesco Saverio Tedesco, University College London: “Reprogramming stem cell-based strategies for skeletal muscle repair and (re)generation”
Read more05 Sep 2018
event
PhD Thesis defense: “Implication of DNA damage and repair in viability and differentiation of muscle stem cells”
Read more27 Jul 2018
publication
Distinct metabolic states govern skeletal muscle stem cell fates during prenatal and postnatal myogenesis
Read more12 Apr 2018
06 Apr 2018
15 Feb 2018
publication
Mitochondrial MDM2 Regulates Respiratory Complex I Activity Independently of p53
Read more01 Feb 2018
21 Nov 2017
publication
Helicobacter pylori targets mitochondrial import and components of mitochondrial DNA replication machinery through an alternative VacA-dependent and a VacA-independent mechanisms
Read more27 Apr 2017
publication
A novel paradigm links mitochondrial dysfunction with muscle stem cell impairment in sepsis
Read more16 Feb 2017
08 Jul 2016
publication
How stem cells manage to escape senescence and ageing – while they can: A recent study reveals that autophagy is responsible for senescence-dependent loss of regenerative potential of muscle stem cells during ageing
Read more24 May 2016
24 May 2016
event
17th International Conference on Oxidative Stress Reduction, Redox Homeostasis and Antioxidants
Read more24 May 2016
01 Jan 2016
publication
A Single-Cell Resolution Imaging Protocol of Mitochondrial DNA Dynamics in Physiopathology, mTRIP, Which Also Evaluates Sublethal Cytotoxicity
Read more15 Dec 2015
publication
Sepsis induces long-term metabolic and mitochondrial muscle stem cell dysfunction amenable by mesenchymal stem cell therapy
Read more13 Oct 2015
16 Jul 2015
18 May 2015
publication
Reversal of mitochondrial defects with CSB-dependent serine protease inhibitors in patient cells of the progeroid Cockayne syndrome
Read more11 May 2015
01 Jan 2015
publication
mTRIP: an imaging tool to investigate mitochondrial DNA dynamics in physiology and disease at the single-cell resolution
Read more01 Nov 2014
publication
Replication of mitochondrial DNA: the art of staying paired to avoid dangerous changes (comment on DOI 10.1002/bies.201400052)
Read more26 Aug 2014
publication
More efficient repair of DNA double-strand breaks in skeletal muscle stem cells compared to their committed progeny
Read more20 Jun 2014
publication
Nitroso-redox balance and mitochondrial homeostasis are regulated by STOX1, a pre-eclampsia-associated gene
Read more04 Jun 2014
23 Jan 2013
publication
Prevalent coordination of mitochondrial DNA transcription and initiation of replication with the cell cycle
Read more13 Dec 2012
publication
Large heterogeneity of mitochondrial DNA transcription and initiation of replication exposed by single-cell imaging
Read more12 Jun 2012
publication
Skeletal muscle stem cells adopt a dormant cell state post mortem and retain regenerative capacity
Read more08 Nov 2011
publication
DNA polymerase μ is a global player in the repair of non-homologous end-joining substrates
Read more08 Mar 2011
14 Oct 2010
publication
Lack of DNA polymerase μ affects the kinetics of DNA double-strand break repair and impacts on cellular senescence
Read more19 Jan 2010
26 Oct 2007
publication
Low joining efficiency and non-conservative repair of two distant double-strand breaks in mouse embryonic stem cells
Read more07 Sep 2004
01 May 2003
publication
Distance from the chromosome end determines the efficiency of double strand break repair in subtelomeres of haploid yeast
Read more01 Nov 1999
15 Aug 1997
26 Nov 1996
publication
A reiterative mode of DNA synthesis adopted by HIV-1 reverse transcriptase after a misincorporation
Read more18 Jul 1995
publication
Homologous recombination promoted by reverse transcriptase during copying of two distinct RNA templates
Read more01 Jun 1993
publication
Comparison of interactions of 5′-derivatives of deoxyoctathymidylate with human DNA polymerize alpha and HIV reverse transcriptase
Read more01 Feb 1993
01 May 1990
publication
Reverse transcriptases and genomic variability: the accuracy of DNA replication is enzyme specific and sequence dependent
Read more20 Dec 1988
publication
DNA-dependent RNA polymerase of Escherichia coli induces bending or an increased flexibility of DNA by specific complex formation
Read more01 Jul 1988
publication
One-dimensional diffusion of Escherichia coli DNA-dependent RNA polymerase: a mechanism to facilitate promoter location
Read more01 Jan 1984
publication