Timeline

Miria Ricchetti
Group Leader
06 Dec 2019
publication

CSB promoter downregulation via histone H3 hypoacetylation is an early determinant of replicative senescence

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25 Mar 2019
event

Developmental and Stem Cell Biology Department seminar by: Professor Juan-Carlos Izpisua Belmonte, Salk Institute for Biological Studies, La Jolla California

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09 Nov 2018
publication

Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells

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07 Sep 2018
event

Extra seminar by Francesco Saverio Tedesco, University College London: “Reprogramming stem cell-based strategies for skeletal muscle repair and (re)generation”

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05 Sep 2018
event

PhD Thesis defense: “Implication of DNA damage and repair in viability and differentiation of muscle stem cells”

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27 Jul 2018
publication

Distinct metabolic states govern skeletal muscle stem cell fates during prenatal and postnatal myogenesis

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12 Apr 2018
publication

Loss of heterogeneity, quiescence, and differentiation in muscle stem cells

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06 Apr 2018
publication

Endonuclease G promotes mitochondrial genome cleavage and replication

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15 Feb 2018
publication

Mitochondrial MDM2 Regulates Respiratory Complex I Activity Independently of p53

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01 Feb 2018
publication

Replication stress in mitochondria

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21 Nov 2017
publication

Helicobacter pylori targets mitochondrial import and components of mitochondrial DNA replication machinery through an alternative VacA-dependent and a VacA-independent mechanisms

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27 Apr 2017
publication

A novel paradigm links mitochondrial dysfunction with muscle stem cell impairment in sepsis

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08 Jul 2016
publication

How stem cells manage to escape senescence and ageing – while they can: A recent study reveals that autophagy is responsible for senescence-dependent loss of regenerative potential of muscle stem cells during ageing

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24 May 2016
project

DNA repair in muscle stem cells and during cell differentiation

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24 May 2016
event

17th International Conference on Oxidative Stress Reduction, Redox Homeostasis and Antioxidants

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24 May 2016
project

Mechanism of ageing and progeroid diseases

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01 Jan 2016
publication

A Single-Cell Resolution Imaging Protocol of Mitochondrial DNA Dynamics in Physiopathology, mTRIP, Which Also Evaluates Sublethal Cytotoxicity

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15 Dec 2015
publication

Sepsis induces long-term metabolic and mitochondrial muscle stem cell dysfunction amenable by mesenchymal stem cell therapy

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13 Oct 2015
project

Muscle Stem Cells & Sepsis

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16 Jul 2015
team

Group: Miria Ricchetti

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18 May 2015
publication

Reversal of mitochondrial defects with CSB-dependent serine protease inhibitors in patient cells of the progeroid Cockayne syndrome

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11 May 2015
team

Stem Cells And Development

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01 Jan 2015
publication

mTRIP: an imaging tool to investigate mitochondrial DNA dynamics in physiology and disease at the single-cell resolution

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01 Nov 2014
publication

Replication of mitochondrial DNA: the art of staying paired to avoid dangerous changes (comment on DOI 10.1002/bies.201400052)

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26 Aug 2014
publication

More efficient repair of DNA double-strand breaks in skeletal muscle stem cells compared to their committed progeny

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20 Jun 2014
publication

Nitroso-redox balance and mitochondrial homeostasis are regulated by STOX1, a pre-eclampsia-associated gene

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04 Jun 2014
publication

Are mitochondria the Achilles’ heel of the Kingdom Fungi?

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23 Jan 2013
publication

Prevalent coordination of mitochondrial DNA transcription and initiation of replication with the cell cycle

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13 Dec 2012
publication

Large heterogeneity of mitochondrial DNA transcription and initiation of replication exposed by single-cell imaging

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12 Jun 2012
publication

Skeletal muscle stem cells adopt a dormant cell state post mortem and retain regenerative capacity

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08 Nov 2011
publication

DNA polymerase μ is a global player in the repair of non-homologous end-joining substrates

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08 Mar 2011
publication

Nuclear mitochondrial DNA activates replication in Saccharomyces cerevisiae

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14 Oct 2010
publication

Lack of DNA polymerase μ affects the kinetics of DNA double-strand break repair and impacts on cellular senescence

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19 Jan 2010
publication

An end-joining repair mechanism in Escherichia coli

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26 Oct 2007
publication

Low joining efficiency and non-conservative repair of two distant double-strand breaks in mouse embryonic stem cells

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07 Sep 2004
publication

Continued colonization of the human genome by mitochondrial DNA

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01 May 2003
publication

Distance from the chromosome end determines the efficiency of double strand break repair in subtelomeres of haploid yeast

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01 Nov 1999
publication

Mitochondrial DNA repairs double-strand breaks in yeast chromosomes

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15 Aug 1997
publication

Telomerase activity of reverse transcriptase

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26 Nov 1996
publication

A reiterative mode of DNA synthesis adopted by HIV-1 reverse transcriptase after a misincorporation

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18 Jul 1995
publication

Homologous recombination promoted by reverse transcriptase during copying of two distinct RNA templates

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01 Jun 1993
publication

Comparison of interactions of 5′-derivatives of deoxyoctathymidylate with human DNA polymerize alpha and HIV reverse transcriptase

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01 Feb 1993
publication

E. coli DNA polymerase I as a reverse transcriptase

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01 May 1990
publication

Reverse transcriptases and genomic variability: the accuracy of DNA replication is enzyme specific and sequence dependent

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20 Dec 1988
publication

DNA-dependent RNA polymerase of Escherichia coli induces bending or an increased flexibility of DNA by specific complex formation

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01 Jul 1988
publication

One-dimensional diffusion of Escherichia coli DNA-dependent RNA polymerase: a mechanism to facilitate promoter location

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01 Jan 1984
publication

Piliated Bacteroides fragilis strains adhere to epithelial cells and are more sensitive to phagocytosis by human neutrophils than nonpiliated strains

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