Timeline

Najma Rachidi
Permanent Researcher
11 Jul 2023
event

First international conference on CK1 PROTEIN KINASES: “FROM CELL SIGNALING TO THERAPEUTIC TARGETS IN HUMAN DISEASE”

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05 Apr 2023
event

Symposium on Microbial Extracellular Vesicles ; June 15th, 2023 ; Auditorium François Jacob

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27 Sep 2022
project

ANR Texleish: Targeting host-parasite interactions through the inhibition of excreted leishmania casein kinase 1

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22 Sep 2022
project

Pasteur-Weizmann project: Role of kinases in vesicle-mediated regulation of host-pathogen interactions: Focus on Leishmania donovani and Plasmodium falciparum.

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22 Sep 2022
project

Parafrap grant : Studying two complementary infection models to identify common mechanisms of intracellular parasite survival: The roles of Leishmania and Eimeria exo-kinases in subversion of host cell signalling.

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20 Sep 2022
project

Campus France procope: CASEIN KINASE 1, A KEY REGULATOR OF TUMORIGENESIS AND HOST-PATHOGEN INTERACTIONS

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31 May 2022
event

DPT Parasites and insects Vectors Seminar – Neta Regev Rudzki “How malaria parasite tricks its hots”

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08 Feb 2022
team

Signalling and host-parasite interactions

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01 Jan 2022
publication

Released Parasite-Derived Kinases as Novel Targets for Antiparasitic Therapies.

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15 Jan 2021
publication

In vitro identification of imidazo[1,2-a]pyrazine-based antileishmanial agents and evaluation of L. major casein kinase 1 inhibition.

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01 Jan 2021
publication

Identification of the Host Substratome of Leishmania-Secreted Casein Kinase 1 Using a SILAC-Based Quantitative Mass Spectrometry Assay.

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01 Jan 2021
publication

Dangerous Duplicity: The Dual Functions of Casein Kinase 1 in Parasite Biology and Host Subversion.

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20 Feb 2020
publication

SILAC-based quantitative proteomics reveals pleiotropic, phenotypic modulation in primary murine macrophages infected with the protozoan pathogen Leishmania donovani.

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24 Oct 2019
event

Symposium “The future of Parasitology”

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05 Oct 2019
publication

Structure, regulation, and (patho-)physiological functions of the stress-induced protein kinase CK1 delta (CSNK1D).

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01 Sep 2019
publication

The kinase domain of CK1δ can be phosphorylated by Chk1.

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22 Aug 2019
event

PhD Defense – Daniel MARTEL -20th September 2019 at 9am: “Functional characterisation of Leishmania casein kinase 1.2 in the parasite and the mammalian host”

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18 Apr 2019
publication

CRISPR in Parasitology: Not Exactly Cut and Dried!

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25 Mar 2019
publication

Leishmania donovani 90 kD Heat Shock Protein – Impact of Phosphosites on Parasite Fitness, Infectivity and Casein Kinase Affinity.

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24 Aug 2018
event

CRISPR in Parasitology Symposium

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29 Nov 2017
publication

Characterisation of Casein Kinase 1.1 in Leishmania donovani Using the CRISPR Cas9 Toolkit.

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08 Jun 2017
publication

The enemy within: Targeting host-parasite interaction for antileishmanial drug discovery.

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02 Jul 2016
publication

Species- and Strain-Specific Adaptation of the HSP70 Super Family in Pathogenic Trypanosomatids.

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01 May 2016
publication

From Drug Screening to Target Deconvolution: a Target-Based Drug Discovery Pipeline Using Leishmania Casein Kinase 1 Isoform 2 To Identify Compounds with Antileishmanial Activity.

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07 Sep 2015
project

FP7 Targeting the Leishmania kinome for the development of novel anti-parasitic strategies (LeishDrug)

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07 Sep 2015
project

ANR TransLeish – Discovery of druggable protein kinases in the protozoan parasite Leishmania donovani using hit compounds identified by phenotypic screening

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07 Sep 2015
project

ANR TranSig – Trans-signalling: A novel mechanism of Leishmania host cell immune evasion through the release of parasite signalling proteins

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07 Sep 2015
project

PTR 539 – A multilevel systems approach to elucidate the host-Leishmania interactome and to identify host targets for anti-leishmanial drug discovery

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11 May 2015
team

Molecular Parasitology and Signaling

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08 Apr 2015
publication

A touch of Zen: post-translational regulation of the Leishmania stress response.

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01 Sep 2014
publication

Transgenic analysis of the Leishmania MAP kinase MPK10 reveals an auto-inhibitory mechanism crucial for stage-regulated activity and parasite viability.

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01 Jul 2014
publication

Probing druggability and biological function of essential proteins in Leishmania combining facilitated null mutant and plasmid shuffle analyses.

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18 Feb 2014
publication

Phosphorylation of Sli15 by Ipl1 is important for proper CPC localization and chromosome stability in Saccharomyces cerevisiae.

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01 Jan 2014
publication

Pharmacological assessment defines Leishmania donovani casein kinase 1 as a drug target and reveals important functions in parasite viability and intracellular infection.

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21 Dec 2012
publication

Apoptotic marker expression in the absence of cell death in staurosporine-treated Leishmania donovani.

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02 Nov 2012
publication

Synthesis and biological evaluation of 2,3-diarylimidazo[1,2-a]pyridines as antileishmanial agents.

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01 Dec 2009
publication

Ipl1-dependent phosphorylation of Dam1 is reduced by tension applied on kinetochores.

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15 May 2007
publication

Ipl1p-dependent phosphorylation of Mad3p is required for the spindle checkpoint response to lack of tension at kinetochores.

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01 Dec 2005
publication

Global analysis of protein phosphorylation in yeast.

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08 Feb 2002
publication

Evidence that the Ipl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections.

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01 Mar 2000
publication

Saccharomyces cerevisiae PAU genes are induced by anaerobiosis.

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01 Jan 2000
publication

Examination of the transcriptional specificity of an enological yeast. A pilot experiment on the chromosome-III right arm.

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01 Jun 1999
publication

Multiple Ty-mediated chromosomal translocations lead to karyotype changes in a wine strain of Saccharomyces cerevisiae.

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18 Jul 1997
publication

Membrane potential-generating malate (MleP) and citrate (CitP) transporters of lactic acid bacteria are homologous proteins. Substrate specificity of the 2-hydroxycarboxylate transporter family.

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