Ligne de temps
Najma Rachidi
Chercheur(euse) Permanent(e)
11 juil. 2023
event
First international conference on CK1 PROTEIN KINASES: “FROM CELL SIGNALING TO THERAPEUTIC TARGETS IN HUMAN DISEASE”
Lire plus05 avr. 2023
event
Symposium on Microbial Extracellular Vesicles ; June 15th, 2023 ; Auditorium François Jacob
Lire plus27 sept. 2022
project
ANR Texleish: Targeting host-parasite interactions through the inhibition of excreted leishmania casein kinase 1
Lire plus22 sept. 2022
project
Pasteur-Weizmann project: Role of kinases in vesicle-mediated regulation of host-pathogen interactions: Focus on Leishmania donovani and Plasmodium falciparum.
Lire plus22 sept. 2022
project
Parafrap grant : Studying two complementary infection models to identify common mechanisms of intracellular parasite survival: The roles of Leishmania and Eimeria exo-kinases in subversion of host cell signalling.
Lire plus20 sept. 2022
project
Campus France procope: CASEIN KINASE 1, A KEY REGULATOR OF TUMORIGENESIS AND HOST-PATHOGEN INTERACTIONS
Lire plus31 mai 2022
event
DPT Parasites and insects Vectors Seminar – Neta Regev Rudzki “How malaria parasite tricks its hots”
Lire plus08 févr. 2022
01 janv. 2022
publication
Released Parasite-Derived Kinases as Novel Targets for Antiparasitic Therapies.
Lire plus15 janv. 2021
publication
In vitro identification of imidazo[1,2-a]pyrazine-based antileishmanial agents and evaluation of L. major casein kinase 1 inhibition.
Lire plus01 janv. 2021
publication
Dangerous Duplicity: The Dual Functions of Casein Kinase 1 in Parasite Biology and Host Subversion.
Lire plus01 janv. 2021
publication
Identification of the Host Substratome of Leishmania-Secreted Casein Kinase 1 Using a SILAC-Based Quantitative Mass Spectrometry Assay.
Lire plus20 févr. 2020
publication
SILAC-based quantitative proteomics reveals pleiotropic, phenotypic modulation in primary murine macrophages infected with the protozoan pathogen Leishmania donovani.
Lire plus24 oct. 2019
05 oct. 2019
publication
Structure, regulation, and (patho-)physiological functions of the stress-induced protein kinase CK1 delta (CSNK1D).
Lire plus01 sept. 2019
22 août 2019
event
PhD Defense – Daniel MARTEL -20th September 2019 at 9am: “Functional characterisation of Leishmania casein kinase 1.2 in the parasite and the mammalian host”
Lire plus18 avr. 2019
25 mars 2019
publication
Leishmania donovani 90 kD Heat Shock Protein – Impact of Phosphosites on Parasite Fitness, Infectivity and Casein Kinase Affinity.
Lire plus24 août 2018
29 nov. 2017
publication
Characterisation of Casein Kinase 1.1 in Leishmania donovani Using the CRISPR Cas9 Toolkit.
Lire plus08 juin 2017
publication
The enemy within: Targeting host-parasite interaction for antileishmanial drug discovery.
Lire plus02 juil. 2016
publication
Species- and Strain-Specific Adaptation of the HSP70 Super Family in Pathogenic Trypanosomatids.
Lire plus01 mai 2016
publication
From Drug Screening to Target Deconvolution: a Target-Based Drug Discovery Pipeline Using Leishmania Casein Kinase 1 Isoform 2 To Identify Compounds with Antileishmanial Activity.
Lire plus07 sept. 2015
project
FP7 Targeting the Leishmania kinome for the development of novel anti-parasitic strategies (LeishDrug)
Lire plus07 sept. 2015
project
ANR TransLeish – Discovery of druggable protein kinases in the protozoan parasite Leishmania donovani using hit compounds identified by phenotypic screening
Lire plus07 sept. 2015
project
ANR TranSig – Trans-signalling: A novel mechanism of Leishmania host cell immune evasion through the release of parasite signalling proteins
Lire plus07 sept. 2015
project
PTR 539 – A multilevel systems approach to elucidate the host-Leishmania interactome and to identify host targets for anti-leishmanial drug discovery
Lire plus11 mai 2015
08 avr. 2015
publication
A touch of Zen: post-translational regulation of the Leishmania stress response.
Lire plus01 sept. 2014
publication
Transgenic analysis of the Leishmania MAP kinase MPK10 reveals an auto-inhibitory mechanism crucial for stage-regulated activity and parasite viability.
Lire plus01 juil. 2014
publication
Probing druggability and biological function of essential proteins in Leishmania combining facilitated null mutant and plasmid shuffle analyses.
Lire plus18 févr. 2014
publication
Phosphorylation of Sli15 by Ipl1 is important for proper CPC localization and chromosome stability in Saccharomyces cerevisiae.
Lire plus01 janv. 2014
publication
Pharmacological assessment defines Leishmania donovani casein kinase 1 as a drug target and reveals important functions in parasite viability and intracellular infection.
Lire plus21 déc. 2012
publication
Apoptotic marker expression in the absence of cell death in staurosporine-treated Leishmania donovani.
Lire plus02 nov. 2012
publication
Synthesis and biological evaluation of 2,3-diarylimidazo[1,2-a]pyridines as antileishmanial agents.
Lire plus01 déc. 2009
publication
Ipl1-dependent phosphorylation of Dam1 is reduced by tension applied on kinetochores.
Lire plus15 mai 2007
publication
Ipl1p-dependent phosphorylation of Mad3p is required for the spindle checkpoint response to lack of tension at kinetochores.
Lire plus01 déc. 2005
08 févr. 2002
publication
Evidence that the Ipl1-Sli15 (Aurora kinase-INCENP) complex promotes chromosome bi-orientation by altering kinetochore-spindle pole connections.
Lire plus01 mars 2000
01 janv. 2000
publication
Examination of the transcriptional specificity of an enological yeast. A pilot experiment on the chromosome-III right arm.
Lire plus01 juin 1999
publication
Multiple Ty-mediated chromosomal translocations lead to karyotype changes in a wine strain of Saccharomyces cerevisiae.
Lire plus18 juil. 1997
publication