Timeline

Lars Rogge
Head of Structure
19 Mar 2019
publication

Anti-TNF Therapy in Spondyloarthritis and Related Diseases, Impact on the Immune System and Prediction of Treatment Responses

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17 Oct 2018
publication

Brief Report: Interleukin-17 Blockade With Secukinumab in Peripheral Spondyloarthritis Impacts Synovial Immunopathology Without Compromising Systemic Immune Responses

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27 Sep 2018
publication

Expansion of Interleukin-22- and Granulocyte-Macrophage Colony-Stimulating Factor-Expressing, but Not Interleukin-17A-Expressing, Group 3 Innate Lymphoid Cells in the Inflamed Joints of Patients With Spondyloarthritis

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23 Feb 2018
publication

Natural variation in the parameters of innate immune cells is preferentially driven by genetic factors

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24 Nov 2017
publication

Regulatory T cells control toxicity in a humanized model of IL-2 therapy

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19 Mar 2017
news

‘ILC-poiesis’: A new model of human ILC differentiation

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09 Mar 2017
publication

Systemic Human ILC Precursors Provide a Substrate for Tissue ILC Differentiation

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14 Mar 2016
publication

IL-12 drives functional plasticity of human group 2 innate lymphoid cells

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28 Jul 2015
patent

Seronegative spondyloarthropathy diagnosis and treatment (WO/2015/010744)

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28 Jul 2015
project

Exploring immunological mechanisms of graft-versus-host disease and of functional immune tolerance in patients after allogeneic hematopoietic stem cell transplantation

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07 Jul 2015
project

Multiparameter single-cell profiling of human CD4+FOXP3+ regulatory T-cell populations in homeostatic conditions and during graft-versus-host disease

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07 Jul 2015
project

Epigenetic mechanisms controlling the stability and plasticity of CD4+ T cell subsets

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06 Jul 2015
project

Linking genotype, cell function and pathology in inflammatory diseases

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11 May 2015
team

Immunoregulation

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07 Jan 2015
publication

Automated flow cytometric analysis across large numbers of samples and cell types

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06 Jan 2015
publication

Semi-automated and standardized cytometric procedures for multi-panel and multi-parametric whole blood immunophenotyping

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20 Mar 2014
publication

Functional analysis via standardized whole-blood stimulation systems defines the boundaries of a healthy immune response to complex stimuli

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01 Jul 2013
publication

Multiparameter single-cell profiling of human CD4+FOXP3+ regulatory T-cell populations in homeostatic conditions and during graft-versus-host disease

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01 Jun 2013
publication

Combinatorial control of Th17 and Th1 cell functions by genetic variations in genes associated with the interleukin-23 signaling pathway in spondyloarthritis

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08 Apr 2011
publication

Proinflammatory environment dictates the IL-17-producing capacity of human invariant NKT cells

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24 May 2010
publication

In vivo expansion of naive and activated CD4+CD25+FOXP3+ regulatory T cell populations in interleukin-2-treated HIV patients

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08 Apr 2010
publication

The human COP9 signalosome protects ubiquitin-conjugating enzyme 3 (UBC3/Cdc34) from beta-transducin repeat-containing protein (betaTrCP)-mediated degradation

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15 Dec 2009
publication

Integration of distinct intracellular signaling pathways at distal regulatory elements directs T-bet expression in human CD4+ T cells

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01 Jun 2009
publication

Genetic and epigenetic networks controlling T helper 1 cell differentiation

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01 Nov 2008
publication

Jakmip1 is expressed upon T cell differentiation and has an inhibitory function in cytotoxic T lymphocytes

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16 May 2007
publication

Long oligonucleotide microarrays for African green monkey gene expression profile analysis

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15 Feb 2007
publication

Chromatin remodeling by the SWI/SNF-like BAF complex and STAT4 activation synergistically induce IL-12Rbeta2 expression during human Th1 cell differentiation

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01 Oct 2006
publication

A thymic pathway of mouse natural killer cell development characterized by expression of GATA-3 and CD127

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30 Aug 2006
publication

The COP9 signalosome regulates Skp2 levels and proliferation of human cells

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13 Jan 2004
publication

RanBPM is a phosphoprotein that associates with the plasma membrane and interacts with the integrin LFA-1

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24 Jul 2003
publication

Gene profiling of lymphoma, myeloma, and AML

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21 Jul 2003
publication

Dissecting oncogenes and tyrosine kinases in AML cells

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18 Jul 2003
publication

Antileukemic activity of natural killer cells in allogeneic BMT

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01 Jul 2003
publication

Increased expression of alpha(1,3)-fucosyltransferase-VII and P-selectin binding of synovial fluid T cells in juvenile idiopathic arthritis

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15 Jan 2003
publication

Down-modulation of responses to type I IFN upon T cell activation

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06 Jan 2003
publication

Gene profiling for defining targets for new therapeutics in autoimmune diseases

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01 Dec 2002
publication

A genomic view of helper T cell subsets

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01 May 2000
publication

Transcript imaging of the development of human T helper cells using oligonucleotide arrays

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01 Apr 2000
publication

Integrin LFA-1 interacts with the transcriptional co-activator JAB1 to modulate AP-1 activity

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