Timeline

Elisabetta Bianchi
Group Leader
19 Mar 2019
publication

Anti-TNF Therapy in Spondyloarthritis and Related Diseases, Impact on the Immune System and Prediction of Treatment Responses

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28 Jul 2015
patent

Seronegative spondyloarthropathy diagnosis and treatment (WO/2015/010744)

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16 Jul 2015
team

Group: Elisabetta Bianchi

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07 Jul 2015
project

Epigenetic mechanisms controlling the stability and plasticity of CD4+ T cell subsets

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11 May 2015
team

Immunoregulation

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02 Jun 2014
publication

RanBP9 overexpression accelerates loss of dendritic spines in a mouse model of Alzheimer’s disease

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13 Jan 2014
publication

Dynamic regulation of the COP9 signalosome in response to DNA damage

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01 Jan 2014
publication

RanBP9 overexpression down-regulates phospho-cofilin, causes early synaptic deficits and impaired learning, and accelerates accumulation of amyloid plaques in the mouse brain

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07 Aug 2013
publication

COPS5 (Jab1) protein increases β site processing of amyloid precursor protein and amyloid β peptide generation by stabilizing RanBP9 protein levels

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01 Jul 2013
publication

Multiparameter single-cell profiling of human CD4+FOXP3+ regulatory T-cell populations in homeostatic conditions and during graft-versus-host disease

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26 Jun 2013
publication

RanBP9 Plays a Critical Role in Neonatal Brain Development in Mice

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13 Jun 2013
publication

RanBP9 aggravates synaptic damage in the mouse brain and is inversely correlated to spinophilin levels in Alzheimer’s brain synaptosomes

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01 Jun 2013
publication

Combinatorial control of Th17 and Th1 cell functions by genetic variations in genes associated with the interleukin-23 signaling pathway in spondyloarthritis

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31 Jan 2012
publication

Role of RanBP9 on amyloidogenic processing of APP and synaptic protein levels in the mouse brain

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08 Apr 2010
publication

The human COP9 signalosome protects ubiquitin-conjugating enzyme 3 (UBC3/Cdc34) from beta-transducin repeat-containing protein (betaTrCP)-mediated degradation

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01 Jan 2010
publication

RanBPM regulates the progression of neuronal precursors through M-phase at the surface of the neocortical ventricular zone

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15 Dec 2009
publication

Integration of distinct intracellular signaling pathways at distal regulatory elements directs T-bet expression in human CD4+ T cells

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27 Sep 2009
publication

Regulation of mu opioid receptor internalization by the scaffold protein RanBPM

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03 Sep 2009
publication

A fragment of the scaffolding protein RanBP9 is increased in Alzheimer’s disease brains and strongly potentiates amyloid-beta peptide generation

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01 Jun 2009
publication

Genetic and epigenetic networks controlling T helper 1 cell differentiation

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09 Mar 2009
publication

Heterotrimeric G proteins demonstrate differential sensitivity to beta-arrestin dependent desensitization

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27 Feb 2009
publication

Novel role of RanBP9 in BACE1 processing of amyloid precursor protein and amyloid beta peptide generation

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10 Apr 2008
publication

Enhancement of transactivation activity of Rta of Epstein-Barr virus by RanBPM

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15 Feb 2007
publication

Chromatin remodeling by the SWI/SNF-like BAF complex and STAT4 activation synergistically induce IL-12Rbeta2 expression during human Th1 cell differentiation

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01 Feb 2007
publication

COP9 signalosome subunit 5 (CSN5/Jab1) regulates the development of the Drosophila immune system: effects on Cactus, Dorsal and hematopoiesis

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30 Aug 2006
publication

The COP9 signalosome regulates Skp2 levels and proliferation of human cells

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04 Jan 2006
publication

An intracellular role for the C1q-globular domain

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01 Jul 2004
publication

Expression pattern of the JAB1/CSN5 gene during murine embryogenesis: colocalization with NEDD8

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13 Jan 2004
publication

RanBPM is a phosphoprotein that associates with the plasma membrane and interacts with the integrin LFA-1

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24 Jul 2003
publication

Gene profiling of lymphoma, myeloma, and AML

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21 Jul 2003
publication

Dissecting oncogenes and tyrosine kinases in AML cells

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18 Jul 2003
publication

Antileukemic activity of natural killer cells in allogeneic BMT

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03 Mar 2003
publication

Characterization of human constitutive photomorphogenesis protein 1, a RING finger ubiquitin ligase that interacts with Jun transcription factors and modulates their transcriptional activity

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01 May 2000
publication

Transcript imaging of the development of human T helper cells using oligonucleotide arrays

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01 Apr 2000
publication

Integrin LFA-1 interacts with the transcriptional co-activator JAB1 to modulate AP-1 activity

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15 Sep 1999
publication

A tyrosine-based sorting signal in the beta2 integrin cytoplasmic domain mediates its recycling to the plasma membrane and is required for ligand-supported migration

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01 May 1999
publication

Regulation of lymphocyte traffic by adhesion molecules

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01 Dec 1997
publication

Through and beyond the wall: late steps in leukocyte transendothelial migration

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01 Feb 1997
publication

A novel approach to the identification of genes involved in neo-angiogenesis: implications for graft re-vascularization

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01 Sep 1996
publication

Integrin-dependent induction of functional urokinase receptors in primary T lymphocytes

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01 Apr 1996
publication

CD31/PECAM-1-driven chemokine-independent transmigration of human T lymphocytes

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01 Mar 1995
publication

Immunohistochemical localization of the plasminogen activator inhibitor-1 in breast cancer

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15 Feb 1994
publication

The urokinase receptor is expressed in invasive breast cancer but not in normal breast tissue

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01 Jan 1991
publication

Age-related changes in interleukin 2 responsiveness of resting and activated human mononuclear cells

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01 Aug 1990
publication

Natural killer lines and clones with apparent antigen specificity

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01 Jul 1989
publication

Interleukin 2 and mitogen driven proliferation in human peripheral mononuclear cells: a kinetic analysis

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