Ligne de temps

Elisabetta Bianchi
Chef(fe) de Groupe
26 août 2024
event

Regulation of IL-23R Expression in Human CD4+ T Cells and the Impact of IL-23 Blockade on Immune Responses in Vivo

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14 févr. 2022
publication

Characterization of Blood Mucosal Associated Invariant T (MAIT) cells in Axial Spondyloarthritis and of resident MAITs from control axial enthesis.

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16 déc. 2021
project

SpA23 – Rôle de l’IL-23 dans les maladies chroniques inflammatoires : exploration des mécanismes cellulaires et moléculaires de la signalisation de l’IL-23 dans la spondylarthrite axiale et périphérique

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16 juil. 2021
project

Pso23 – Exploration des mécanismes cellulaires et moléculaires de la réponse chez les patients recevant une biothérapie ciblant l’axe IL-23/IL-17 dans le psoriasis cutané

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01 avr. 2021
publication

Immune response profiling of patients with spondyloarthritis reveals signalling networks mediating TNF-blocker function in vivo.

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01 avr. 2021
publication

Novel approaches to develop biomarkers predicting treatment responses to TNF-blockers.

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01 janv. 2021
publication

Editorial: Role of the IL-23/IL-17 Pathway in Chronic Immune-Mediated Inflammatory Diseases: Mechanisms and Targeted Therapies.

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25 août 2020
publication

Cellular and molecular profiling of T-cell subsets at the onset of human acute GVHD.

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16 oct. 2019
publication

NFAT primes the human RORC locus for RORγt expression in CD4 T cells

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25 juin 2019
publication

The IL-23/IL-17 pathway in human chronic inflammatory diseases – new insight from genetics and targeted therapies

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19 avr. 2019
publication

The IL-23/IL-17 pathway in human chronic inflammatory diseases-new insight from genetics and targeted therapies

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19 mars 2019
publication

Anti-TNF Therapy in Spondyloarthritis and Related Diseases, Impact on the Immune System and Prediction of Treatment Responses

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14 nov. 2015
publication

Bystander hyperactivation of preimmune CD8+ T cells in chronic HCV patients.

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28 juil. 2015
patent

Seronegative spondyloarthropathy diagnosis and treatment (WO/2015/010744)

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07 juil. 2015
project

Epigenetic mechanisms controlling the stability and plasticity of CD4+ T cell subsets

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11 mai 2015
team

Immunorégulation

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02 juin 2014
publication

RanBP9 overexpression accelerates loss of dendritic spines in a mouse model of Alzheimer’s disease

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13 janv. 2014
publication

Dynamic regulation of the COP9 signalosome in response to DNA damage

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01 janv. 2014
publication

RanBP9 overexpression down-regulates phospho-cofilin, causes early synaptic deficits and impaired learning, and accelerates accumulation of amyloid plaques in the mouse brain

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07 août 2013
publication

COPS5 (Jab1) protein increases β site processing of amyloid precursor protein and amyloid β peptide generation by stabilizing RanBP9 protein levels

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01 juil. 2013
publication

Multiparameter single-cell profiling of human CD4+FOXP3+ regulatory T-cell populations in homeostatic conditions and during graft-versus-host disease

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26 juin 2013
publication

RanBP9 Plays a Critical Role in Neonatal Brain Development in Mice

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13 juin 2013
publication

RanBP9 aggravates synaptic damage in the mouse brain and is inversely correlated to spinophilin levels in Alzheimer’s brain synaptosomes

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01 juin 2013
publication

Combinatorial control of Th17 and Th1 cell functions by genetic variations in genes associated with the interleukin-23 signaling pathway in spondyloarthritis

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31 janv. 2012
publication

Role of RanBP9 on amyloidogenic processing of APP and synaptic protein levels in the mouse brain

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08 avr. 2010
publication

The human COP9 signalosome protects ubiquitin-conjugating enzyme 3 (UBC3/Cdc34) from beta-transducin repeat-containing protein (betaTrCP)-mediated degradation

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01 janv. 2010
publication

RanBPM regulates the progression of neuronal precursors through M-phase at the surface of the neocortical ventricular zone

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15 déc. 2009
publication

Integration of distinct intracellular signaling pathways at distal regulatory elements directs T-bet expression in human CD4+ T cells

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27 sept. 2009
publication

Regulation of mu opioid receptor internalization by the scaffold protein RanBPM

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03 sept. 2009
publication

A fragment of the scaffolding protein RanBP9 is increased in Alzheimer’s disease brains and strongly potentiates amyloid-beta peptide generation

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01 juin 2009
publication

Genetic and epigenetic networks controlling T helper 1 cell differentiation

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09 mars 2009
publication

Heterotrimeric G proteins demonstrate differential sensitivity to beta-arrestin dependent desensitization

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27 févr. 2009
publication

Novel role of RanBP9 in BACE1 processing of amyloid precursor protein and amyloid beta peptide generation

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10 avr. 2008
publication

Enhancement of transactivation activity of Rta of Epstein-Barr virus by RanBPM

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15 févr. 2007
publication

Chromatin remodeling by the SWI/SNF-like BAF complex and STAT4 activation synergistically induce IL-12Rbeta2 expression during human Th1 cell differentiation

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01 févr. 2007
publication

COP9 signalosome subunit 5 (CSN5/Jab1) regulates the development of the Drosophila immune system: effects on Cactus, Dorsal and hematopoiesis

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30 août 2006
publication

The COP9 signalosome regulates Skp2 levels and proliferation of human cells

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04 janv. 2006
publication

An intracellular role for the C1q-globular domain

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01 juil. 2004
publication

Expression pattern of the JAB1/CSN5 gene during murine embryogenesis: colocalization with NEDD8

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13 janv. 2004
publication

RanBPM is a phosphoprotein that associates with the plasma membrane and interacts with the integrin LFA-1

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24 juil. 2003
publication

Gene profiling of lymphoma, myeloma, and AML

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21 juil. 2003
publication

Dissecting oncogenes and tyrosine kinases in AML cells

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18 juil. 2003
publication

Antileukemic activity of natural killer cells in allogeneic BMT

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03 mars 2003
publication

Characterization of human constitutive photomorphogenesis protein 1, a RING finger ubiquitin ligase that interacts with Jun transcription factors and modulates their transcriptional activity

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01 mai 2000
publication

Transcript imaging of the development of human T helper cells using oligonucleotide arrays

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01 avr. 2000
publication

Integrin LFA-1 interacts with the transcriptional co-activator JAB1 to modulate AP-1 activity

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15 sept. 1999
publication

A tyrosine-based sorting signal in the beta2 integrin cytoplasmic domain mediates its recycling to the plasma membrane and is required for ligand-supported migration

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01 mai 1999
publication

Regulation of lymphocyte traffic by adhesion molecules

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01 déc. 1997
publication

Through and beyond the wall: late steps in leukocyte transendothelial migration

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01 févr. 1997
publication

A novel approach to the identification of genes involved in neo-angiogenesis: implications for graft re-vascularization

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01 sept. 1996
publication

Integrin-dependent induction of functional urokinase receptors in primary T lymphocytes

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01 avr. 1996
publication

CD31/PECAM-1-driven chemokine-independent transmigration of human T lymphocytes

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01 mars 1995
publication

Immunohistochemical localization of the plasminogen activator inhibitor-1 in breast cancer

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15 févr. 1994
publication

The urokinase receptor is expressed in invasive breast cancer but not in normal breast tissue

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01 janv. 1991
publication

Age-related changes in interleukin 2 responsiveness of resting and activated human mononuclear cells

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01 août 1990
publication

Natural killer lines and clones with apparent antigen specificity

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01 juil. 1989
publication

Interleukin 2 and mitogen driven proliferation in human peripheral mononuclear cells: a kinetic analysis

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