Timeline

Sigolène Meilhac
Head of Structure
02 Nov 2023
program_project

The IP Stem Cell Initiative

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13 Oct 2023
publication

Identification of Greb1l as a genetic determinant of crisscross heart in mice showing torsion of the heart tube by shortage of progenitor cells.

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15 Mar 2023
event

European Developmental Biology Congress 2023

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16 May 2022
publication

Pseudodynamic analysis of heart tube formation in the mouse reveals strong regional variability and early left–right asymmetry

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22 Apr 2022
publication

3D cell morphology detection by association for embryo heart morphogenesis

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10 Jan 2022
publication

Shaping the mouse heart tube from the second heart field epithelium.

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31 Aug 2021
publication

Heart Development and Congenital Structural Heart Defects.

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13 Apr 2021
publication

Nu3D: 3D Nuclei Segmentation from Light-Sheet Microscopy Images of the Embryonic Heart

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25 Mar 2021
news

Highlights 2020

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23 Nov 2020
publication

Transient Nodal Signaling in Left Precursors Coordinates Opposed Asymmetries Shaping the Heart Loop.

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12 Oct 2020
publication

Mesoderm patterning by a dynamic gradient of retinoic acid signalling.

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21 Jul 2020
publication

Intraflagellar Transport Complex B Proteins Regulate the Hippo Effector Yap1 during Cardiogenesis.

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10 Jun 2020
event

DSCB Department seminar: Alessandra Pierani, Institut Imagine – “Transient moving organizers: life and death in cortical development, evolution and pathology”

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04 Oct 2019
event

Thesis Defense: “Mechanism of oriented cell division underlying cardiac chamber expansion” – DANIEL DARBY

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09 Jul 2019
publication

Standardised imaging pipeline for phenotyping mouse laterality defects and associated heart malformations, at multiple scales and multiple stages.

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22 Nov 2018
publication

Left-right asymmetry in heart development and disease: forming the right loop

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01 Nov 2018
publication

The deployment of cell lineages that form the mammalian heart

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16 Feb 2018
event

Department seminar by Sally Horne-Badovinac, from the University of Chicago: “Going in circles gets you somewhere: signaling mechanisms that coordinate individual cell movements for collective migration”

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05 Jan 2018
event

Department seminar by Annarita Miccio, Institut Imagine, Paris: “Dynamics of transcriptional and epigenetic signatures during hematopoietic lineage commitment and differentiation”

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28 Nov 2017
publication

A predictive model of asymmetric morphogenesis from 3D reconstructions of mouse heart looping dynamics.

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09 Mar 2017
event

SEMINAR ” Left-Right asymmetry in Drosophila: from molecular to organism chirality ” by Stéphane Noselli

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25 Nov 2016
news

SEMINAR “How the molecular machinery of pluripotency controls Nodal expression during epiblast maturation”

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16 Sep 2016
news

SEMINAR ” FGFR3 signaling in skeletal development “

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05 Jan 2016
news

SEMINAR “Endothelin pathway and mandibulofacial dysostoses in Human”

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12 Aug 2015
project

Left-right asymmetry of the heart

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09 Jun 2015
project

Mechanism of heart growth

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11 May 2015
team

Heart Morphogenesis

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31 Mar 2015
publication

The more we know, the more we have to discover: an exciting future for understanding cilia and ciliopathies

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07 Mar 2015
publication

Imaging and analyzing primary cilia in cardiac cells

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02 Feb 2015
publication

Cardiac cell lineages that form the heart

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10 Nov 2014
publication

[Cilia and heart morphogenesis]

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06 Oct 2014
publication

Integrating multi-scale knowledge on cardiac development into a computational model of ventricular trabeculation

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15 Sep 2014
department

Developmental and Stem Cell Biology

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01 Jun 2013
publication

Resolving cell lineage contributions to the ventricular conduction system with a Cx40-GFP allele: a dual contribution of the first and second heart fields.

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21 Jan 2013
publication

Extracting 3D cell parameters from dense tissue environments: application to the development of the mouse heart

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15 Jan 2013
publication

Quantitative analysis of polarity in 3D reveals local cell coordination in the embryonic mouse heart

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05 Sep 2012
publication

Asymmetric fate of the posterior part of the second heart field results in unexpected left/right contributions to both poles of the heart

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01 Aug 2012
publication

Lineage tree for the venous pole of the heart: clonal analysis clarifies controversial genealogy based on genetic tracing

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01 Jan 2012
publication

Cell lineages, growth and repair of the mouse heart

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13 Sep 2011
publication

Tracing cells for tracking cell lineage and clonal behavior

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01 Oct 2010
publication

Clonal analysis reveals common lineage relationships between head muscles and second heart field derivatives in the mouse embryo

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05 May 2009
publication

Active cell movements coupled to positional induction are involved in lineage segregation in the mouse blastocyst

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01 Jan 2008
publication

Myocardium at the base of the aorta and pulmonary trunk is prefigured in the outflow tract of the heart and in subdomains of the second heart field.

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16 Aug 2007
publication

Regionalization of the mouse visceral endoderm as the blastocyst transforms into the egg cylinder

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03 Jul 2007
publication

The anterior visceral endoderm of the mouse embryo is established from both preimplantation precursor cells and by de novo gene expression after implantation

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01 May 2004
publication

The clonal origin of myocardial cells in different regions of the embryonic mouse heart

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01 Jan 2004
publication

Oriented clonal cell growth in the developing mouse myocardium underlies cardiac morphogenesis

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01 Aug 2003
publication

A retrospective clonal analysis of the myocardium reveals two phases of clonal growth in the developing mouse heart

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01 Jan 2003
publication

[The mouse as a model of heart morphogenesis in mammals: origin and lineage of myocytes]

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01 Jan 2003
publication

The formation of skeletal muscle: from somite to limb

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