Ligne de temps

Sigolène Meilhac
Responsable de Structure
21 nov. 2024
news

On Mon 11/18, we held a mini symposium on the novel perspectives in human embryo research and Stem cell day. Lively discussions thanks to our prominent speakers and participants!

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21 nov. 2024
news

On Monday, November 18, we held a Minisymposium on the new perspectives of human embryo research and STEM CELL DAY. Lively discussions thanks to our outstanding speakers and participants!

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21 nov. 2024
news

On Mon 11/18, we held a Mini-Symposium: “The Human Embryo: Novel Perspectives in Research and Disease Mechanisms” and STEM CELL DAY. Lively discussions thanks to our prominent speakers and participants!

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10 avr. 2024
publication

Deep learning-based detection of murine congenital heart defects from µCT scans

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28 mars 2024
publication

Notch3 is a genetic modifier of NODAL signalling for patterning asymmetry during mouse heart looping

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26 mars 2024
event

The human embryo : novel perspectives in research and disease mechanisms

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04 mars 2024
publication

Inactivation of cytidine triphosphate synthase 1 prevents fatal auto-immunity in mice.

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02 nov. 2023
program_project

Initiative Cellules Souches

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13 oct. 2023
publication

Identification of Greb1l as a genetic determinant of crisscross heart in mice showing torsion of the heart tube by shortage of progenitor cells.

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15 mars 2023
event

European Developmental Biology Congress 2023

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01 janv. 2023
publication

Origin of congenital coronary arterio-ventricular fistulae from anomalous epicardial and myocardial development.

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16 mai 2022
publication

Pseudodynamic analysis of heart tube formation in the mouse reveals strong regional variability and early left–right asymmetry

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22 avr. 2022
publication

3D cell morphology detection by association for embryo heart morphogenesis

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01 avr. 2022
publication

Shaping the mouse heart tube from the second heart field epithelium

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31 août 2021
publication

Heart Development and Congenital Structural Heart Defects.

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13 avr. 2021
publication

Nu3D: 3D Nuclei Segmentation from Light-Sheet Microscopy Images of the Embryonic Heart

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25 mars 2021
news

Highlights 2020

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23 nov. 2020
publication

Transient Nodal Signaling in Left Precursors Coordinates Opposed Asymmetries Shaping the Heart Loop.

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12 oct. 2020
publication

Mesoderm patterning by a dynamic gradient of retinoic acid signalling.

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21 juil. 2020
publication

Intraflagellar Transport Complex B Proteins Regulate the Hippo Effector Yap1 during Cardiogenesis.

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10 juin 2020
event

DSCB Department seminar: Alessandra Pierani, Institut Imagine – “Transient moving organizers: life and death in cortical development, evolution and pathology”

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04 oct. 2019
event

Thesis Defense: “Mechanism of oriented cell division underlying cardiac chamber expansion” – DANIEL DARBY

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09 juil. 2019
publication

Standardised imaging pipeline for phenotyping mouse laterality defects and associated heart malformations, at multiple scales and multiple stages.

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22 nov. 2018
publication

Left-right asymmetry in heart development and disease: forming the right loop

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01 nov. 2018
publication

The deployment of cell lineages that form the mammalian heart.

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16 févr. 2018
event

Department seminar by Sally Horne-Badovinac, from the University of Chicago: “Going in circles gets you somewhere: signaling mechanisms that coordinate individual cell movements for collective migration”

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05 janv. 2018
event

Department seminar by Annarita Miccio, Institut Imagine, Paris: “Dynamics of transcriptional and epigenetic signatures during hematopoietic lineage commitment and differentiation”

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28 nov. 2017
publication

A predictive model of asymmetric morphogenesis from 3D reconstructions of mouse heart looping dynamics.

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09 mars 2017
event

SEMINAR ” Left-Right asymmetry in Drosophila: from molecular to organism chirality ” by Stéphane Noselli

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25 nov. 2016
news

SEMINAR “How the molecular machinery of pluripotency controls Nodal expression during epiblast maturation”

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16 sept. 2016
news

SEMINAR ” FGFR3 signaling in skeletal development “

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05 janv. 2016
news

SEMINAR “Endothelin pathway and mandibulofacial dysostoses in Human”

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12 août 2015
project

Left-right asymmetry of the heart

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09 juin 2015
project

Mechanism of heart growth

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11 mai 2015
team

Morphogenèse du coeur

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31 mars 2015
publication

The more we know, the more we have to discover: an exciting future for understanding cilia and ciliopathies

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07 mars 2015
publication

Imaging and analyzing primary cilia in cardiac cells

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02 févr. 2015
publication

Cardiac cell lineages that form the heart

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10 nov. 2014
publication

[Cilia and heart morphogenesis]

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06 oct. 2014
publication

Integrating multi-scale knowledge on cardiac development into a computational model of ventricular trabeculation

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15 sept. 2014
department

Biologie du développement et cellules souches

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01 juin 2013
publication

Resolving cell lineage contributions to the ventricular conduction system with a Cx40-GFP allele: a dual contribution of the first and second heart fields.

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21 janv. 2013
publication

Extracting 3D cell parameters from dense tissue environments: application to the development of the mouse heart

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15 janv. 2013
publication

Quantitative analysis of polarity in 3D reveals local cell coordination in the embryonic mouse heart

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05 sept. 2012
publication

Asymmetric fate of the posterior part of the second heart field results in unexpected left/right contributions to both poles of the heart

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01 août 2012
publication

Lineage tree for the venous pole of the heart: clonal analysis clarifies controversial genealogy based on genetic tracing

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01 janv. 2012
publication

Cell lineages, growth and repair of the mouse heart

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13 sept. 2011
publication

Tracing cells for tracking cell lineage and clonal behavior

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05 mai 2009
publication

Active cell movements coupled to positional induction are involved in lineage segregation in the mouse blastocyst

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01 janv. 2008
publication

Myocardium at the base of the aorta and pulmonary trunk is prefigured in the outflow tract of the heart and in subdomains of the second heart field.

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16 août 2007
publication

Regionalization of the mouse visceral endoderm as the blastocyst transforms into the egg cylinder

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03 juil. 2007
publication

The anterior visceral endoderm of the mouse embryo is established from both preimplantation precursor cells and by de novo gene expression after implantation

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