Timeline
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Alain Jacquier
Head of Structure
06 Dec 2021
news
Congratulation to Alain Jacquier for receiving the Prix André Goffeau – 2021 Medal of the Société Française de Génétique
Read more22 Oct 2021
24 Sep 2021
news
Highlighted Publication : “Investigation of RNA metabolism through large-scale genetic interaction profiling in yeast”, Decourty, L et al., NAR, 2021 Sep 7;49(15) – Genetics of Macromolecular Interactions team
Read more07 Sep 2021
publication
Investigation of RNA metabolism through large-scale genetic interaction profiling in yeast.
Read more05 Oct 2020
publication
Investigation of RNA metabolism through large-scale genetic interaction profiling in yeast
Read more31 Jan 2020
07 Jun 2019
publication
A specialised SKI complex assists the cytoplasmic RNA exosome in the absence of direct association with ribosomes
Read more25 Mar 2019
01 Oct 2018
18 May 2018
publication
Antisense transcriptional interference mediates condition-specific gene repression in budding yeast
Read more17 Mar 2017
publication
Exposure to selenomethionine causes selenocysteine misincorporation and protein aggregation in Saccharomyces cerevisiae
Read more15 Mar 2017
publication
The ribosome-bound quality control complex remains associated to aberrant peptides during their proteasomal targeting and interacts with Tom1 to limit protein aggregation
Read more16 Dec 2016
13 Sep 2016
event
The zinc cluster proteins: a fungal family of transcriptional regulators with functions ranging from carbon metabolism to drug resistance
Read more27 Apr 2016
18 Apr 2016
publication
Rqc1 and Ltn1 Prevent C-terminal Alanine-Threonine Tail (CAT-tail)-induced Protein Aggregation by Efficient Recruitment of Cdc48 on Stalled 60S Subunits
Read more09 Jun 2015
23 Apr 2015
publication
Quality control of transcription start site selection by nonsense-mediated-mRNA decay
Read more09 Feb 2015
13 Feb 2014
publication
Long open reading frame transcripts escape nonsense-mediated mRNA decay in yeast
Read more21 Nov 2013
13 Aug 2013
publication
Yeast ribosomal protein L7 and its homologue Rlp7 are simultaneously present at distinct sites on pre-60S ribosomal particles
Read more11 Mar 2013
publication
Cdc48-associated complex bound to 60S particles is required for the clearance of aberrant translation products
Read more20 Sep 2012
07 May 2012
13 Apr 2012
publication
The yeast RPL9B gene is regulated by modulation between two modes of transcription termination
Read more01 Apr 2011
publication
Gcn4 misregulation reveals a direct role for the evolutionary conserved EKC/KEOPS in the t6A modification of tRNAs
Read more01 Jan 2011
26 Mar 2010
01 Dec 2009
publication
The complex eukaryotic transcriptome: unexpected pervasive transcription and novel small RNAs
Read more18 Nov 2009
publication
Interaction of yeast eIF4G with spliceosome components: implications in pre-mRNA processing events
Read more23 Oct 2009
publication
Physical and genetic interactions of yeast Cwc21p, an ortholog of human SRm300/SRRM2, suggest a role at the catalytic center of the spliceosome
Read more26 Mar 2009
publication
Cordycepin interferes with 3′ end formation in yeast independently of its potential to terminate RNA chain elongation
Read more25 Jan 2009
publication
Widespread bidirectional promoters are the major source of cryptic transcripts in yeast
Read more01 Sep 2008
publication
Futile cycle of transcription initiation and termination modulates the response to nucleotide shortage in S. cerevisiae
Read more25 Jul 2008
publication
60S ribosomal subunit assembly dynamics defined by semi-quantitative mass spectrometry of purified complexes
Read more30 Jun 2008
publication
A yeast exosome cofactor, Mpp6, functions in RNA surveillance and in the degradation of noncoding RNA transcripts
Read more11 Apr 2008
publication
Linking functionally related genes by sensitive and quantitative characterization of genetic interaction profiles
Read more17 Sep 2007
publication
Hmo1 is required for TOR-dependent regulation of ribosomal protein gene transcription
Read more24 Jul 2007
publication
The Hsp40 chaperone Jjj1 is required for the nucleo-cytoplasmic recycling of preribosomal factors in Saccharomyces cerevisiae
Read more23 Jul 2007
publication
Cytoplasmic recycling of 60S preribosomal factors depends on the AAA protein Drg1
Read more01 Jun 2007
publication
Staphylococcus aureus RNAIII coordinately represses the synthesis of virulence factors and the transcription regulator Rot by an antisense mechanism
Read more16 Feb 2007
publication
The p21-activated protein kinase inhibitor Skb15 and its budding yeast homologue are 60S ribosome assembly factors
Read more21 Jul 2006
publication
Nsa2 is an unstable, conserved factor required for the maturation of 27 SB pre-rRNAs
Read more01 May 2006
publication
A functional network involved in the recycling of nucleocytoplasmic pre-60S factors
Read more01 Jun 2005
publication
RNA degradation by the exosome is promoted by a nuclear polyadenylation complex
Read more01 Jun 2005
publication
The complete set of H/ACA snoRNAs that guide rRNA pseudouridylations in Saccharomyces cerevisiae
Read more01 Jun 2005
publication
Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymerase
Read more27 Jan 2005
publication
Staphylococcus aureus RNAIII and the endoribonuclease III coordinately regulate spa gene expression
Read more01 Jul 2004
09 Feb 2004
publication
Identification of TINO: a new evolutionarily conserved BCL-2 AU-rich element RNA-binding protein
Read more09 Jan 2004
01 Jul 2003
publication
A snoRNA that guides the two most conserved pseudouridine modifications within rRNA confers a growth advantage in yeast
Read more01 Jul 2003
01 Nov 2002
01 Mar 2002
publication
Spc24 interacts with Mps2 and is required for chromosome segregation, but is not implicated in spindle pole body duplication
Read more01 Mar 2002
publication
Nuclear architecture and spatial positioning help establish transcriptional states of telomeres in yeast
Read more15 Nov 2001
publication
Nog2p, a putative GTPase associated with pre-60S subunits and required for late 60S maturation steps
Read more14 Feb 2001
publication