Timeline

Alain Jacquier
Head of Structure
07 Jun 2019
publication

A specialised SKI complex assists the cytoplasmic RNA exosome in the absence of direct association with ribosomes

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25 Mar 2019
publication

Structure of the 80S ribosome-Xrn1 nuclease complex

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12 Feb 2019
team

Genetics of genomes

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01 Oct 2018
publication

Nonsense-mediated mRNA decay involves two distinct Upf1-bound complexes

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18 May 2018
publication

Antisense transcriptional interference mediates condition-specific gene repression in budding yeast

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17 Mar 2017
publication

Exposure to selenomethionine causes selenocysteine misincorporation and protein aggregation in Saccharomyces cerevisiae

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15 Mar 2017
publication

The Ribosome-bound Quality Control complex remains associated to aberrant peptides during their proteasomal targeting and interacts with Tom1 to limit protein aggregation

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16 Dec 2016
publication

The cryo-EM structure of a ribosome-Ski2-Ski3-Ski8 helicase complex

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13 Sep 2016
event

The zinc cluster proteins: a fungal family of transcriptional regulators with functions ranging from carbon metabolism to drug resistance

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27 Apr 2016
publication

How cells kill a “killer” messenger

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18 Apr 2016
publication

Rqc1 and Ltn1 prevent CAT-tail induced protein aggregation by efficient recruitment of Cdc48 on stalled 60S subunits

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29 Sep 2015
project

S. cerevisiae gene regulation in quiescence

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09 Jun 2015
project

Diversity and stability of eukaryotic transcripts

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09 Jun 2015
project

Non-sense mediated mRNA decay mechanisms

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11 May 2015
team

Genetics of Macromolecular Interactions

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23 Apr 2015
publication

Quality control of transcription start site selection by nonsense-mediated-mRNA decay

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09 Feb 2015
project

Genome-wide genetic screens by GIM (Genetic Interactions Mapping)

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13 Feb 2014
publication

Long open reading frame transcripts escape nonsense-mediated mRNA decay in yeast

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21 Nov 2013
publication

Dealing with pervasive transcription

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13 Aug 2013
publication

Yeast ribosomal protein L7 and its homologue Rlp7 are simultaneously present at distinct sites on pre-60S ribosomal particles

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11 Mar 2013
publication

Cdc48-associated complex bound to 60S particles is required for the clearance of aberrant translation products

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20 Sep 2012
publication

Extensive degradation of RNA precursors by the exosome in wild-type cells

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07 May 2012
publication

Sodium selenide toxicity is mediated by O2-dependent DNA breaks

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13 Apr 2012
publication

The yeast RPL9B gene is regulated by modulation between two modes of transcription termination

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01 Apr 2011
publication

Gcn4 misregulation reveals a direct role for the evolutionary conserved EKC/KEOPS in the t6A modification of tRNAs

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01 Jan 2011
publication

Enrichment of unstable non-coding RNAs and their genome-wide identification

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26 Mar 2010
publication

Ecm1 is a new pre-ribosomal factor involved in pre-60S particle export

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01 Dec 2009
publication

The complex eukaryotic transcriptome: unexpected pervasive transcription and novel small RNAs

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18 Nov 2009
publication

Interaction of yeast eIF4G with spliceosome components: implications in pre-mRNA processing events

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23 Oct 2009
publication

Physical and genetic interactions of yeast Cwc21p, an ortholog of human SRm300/SRRM2, suggest a role at the catalytic center of the spliceosome

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26 Mar 2009
publication

Cordycepin interferes with 3′ end formation in yeast independently of its potential to terminate RNA chain elongation

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25 Jan 2009
publication

Widespread bidirectional promoters are the major source of cryptic transcripts in yeast

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01 Sep 2008
publication

Futile cycle of transcription initiation and termination modulates the response to nucleotide shortage in S. cerevisiae

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25 Jul 2008
publication

60S ribosomal subunit assembly dynamics defined by semi-quantitative mass spectrometry of purified complexes

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30 Jun 2008
publication

A yeast exosome cofactor, Mpp6, functions in RNA surveillance and in the degradation of noncoding RNA transcripts

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11 Apr 2008
publication

Linking functionally related genes by sensitive and quantitative characterization of genetic interaction profiles

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17 Sep 2007
publication

Hmo1 is required for TOR-dependent regulation of ribosomal protein gene transcription

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24 Jul 2007
publication

The Hsp40 chaperone Jjj1 is required for the nucleo-cytoplasmic recycling of preribosomal factors in Saccharomyces cerevisiae

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23 Jul 2007
publication

Cytoplasmic recycling of 60S preribosomal factors depends on the AAA protein Drg1

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01 Jun 2007
publication

Staphylococcus aureus RNAIII coordinately represses the synthesis of virulence factors and the transcription regulator Rot by an antisense mechanism

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16 Feb 2007
publication

The p21-activated protein kinase inhibitor Skb15 and its budding yeast homologue are 60S ribosome assembly factors

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24 Nov 2006
publication

GOlorize: a Cytoscape plug-in for network visualization with Gene Ontology-based layout and coloring

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21 Jul 2006
publication

Nsa2 is an unstable, conserved factor required for the maturation of 27 SB pre-rRNAs

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01 May 2006
publication

A functional network involved in the recycling of nucleocytoplasmic pre-60S factors

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01 Jun 2005
publication

RNA degradation by the exosome is promoted by a nuclear polyadenylation complex

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01 Jun 2005
publication

The complete set of H/ACA snoRNAs that guide rRNA pseudouridylations in Saccharomyces cerevisiae

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01 Jun 2005
publication

Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymerase

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27 Jan 2005
publication

Staphylococcus aureus RNAIII and the endoribonuclease III coordinately regulate spa gene expression

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01 Jul 2004
publication

Targeted mRNA degradation by deadenylation-independent decapping

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09 Feb 2004
publication

Identification of TINO: a new evolutionarily conserved BCL-2 AU-rich element RNA-binding protein

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01 Jan 2004
publication

Nuclear retention of unspliced mRNAs in yeast is mediated by perinuclear Mlp1

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01 Jul 2003
publication

A snoRNA that guides the two most conserved pseudouridine modifications within rRNA confers a growth advantage in yeast

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01 Jul 2003
publication

Sequential protein association with nascent 60S ribosomal particles

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01 Nov 2002
publication

Human L1 element target-primed reverse transcription in vitro

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01 Mar 2002
publication

Nuclear architecture and spatial positioning help establish transcriptional states of telomeres in yeast

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01 Mar 2002
publication

Spc24 interacts with Mps2 and is required for chromosome segregation, but is not implicated in spindle pole body duplication

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15 Nov 2001
publication

Nog2p, a putative GTPase associated with pre-60S subunits and required for late 60S maturation steps

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14 Feb 2001
publication

Identification of 12 new yeast mitochondrial ribosomal proteins including 6 that have no prokaryotic homologues

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