The zinc cluster proteins: a fungal family of transcriptional regulators with functions ranging from carbon metabolism to drug resistance - Research - Institut Pasteur

A little guide for advanced search:

Tip 1. You can use quotes "" to search for an exact expression.
Example: "cell division"
Tip 2. You can use + symbol to restrict results containing all words.
Example: +cell +stem
Tip 3. You can use + and - symbols to force inclusion or exclusion of specific words.
Example: +cell -stem

e.g. searching for members in projects tagged cancer

Search for

Count

IN

OUT

Content 1

Content Type

member
team
department
center
program_project
nrc
whocc
project
software
tool
patent

Keywords

Positions

Administrative Staff
Assistant Professor
Associate Professor
Clinical Research Assistant
Clinical Research Nurse
Clinician Researcher
Department Manager
Dual-education Student
Full Professor
Honorary Professor
Lab assistant
Master Student
Non-permanent Researcher
Nursing Staff
Permanent Researcher
Pharmacist
PhD Student
Physician
Post-doc
Prize
Project Manager
Research Associate
Research Engineer
Retired scientist
Technician
Undergraduate Student
Veterinary
Visiting Scientist

Appointments

Deputy Director of Center
Deputy Director of Department
Deputy Director of National Reference Center
Deputy Head of Facility
Director of Center
Director of Department
Director of Institute
Director of National Reference Center
Group Leader
Head of Facility
Head of Operations
Head of Structure
Honorary President of the Departement
Labex Coordinator

Content 2

Content Type

member
team
department
center
program_project
nrc
whocc
project
software
tool
patent

Keywords

Positions

Administrative Staff
Assistant Professor
Associate Professor
Clinical Research Assistant
Clinical Research Nurse
Clinician Researcher
Department Manager
Dual-education Student
Full Professor
Honorary Professor
Lab assistant
Master Student
Non-permanent Researcher
Nursing Staff
Permanent Researcher
Pharmacist
PhD Student
Physician
Post-doc
Prize
Project Manager
Research Associate
Research Engineer
Retired scientist
Technician
Undergraduate Student
Veterinary
Visiting Scientist

Appointments

Deputy Director of Center
Deputy Director of Department
Deputy Director of National Reference Center
Deputy Head of Facility
Director of Center
Director of Department
Director of Institute
Director of National Reference Center
Group Leader
Head of Facility
Head of Operations
Head of Structure
Honorary President of the Departement
Labex Coordinator

Search

EN
FR

Go back

Scroll to top

2015-2016 Institut Pasteur PhD Graduation Ceremony

“Characterization of HRP4: an unusual Leishmania major HSP70-related protein”

Scientific Fields

Diseases

Organisms

Applications

Technique

Date

15

Sep 2016

Time

11:00:00

25-28 Rue du Docteur Roux, Paris, France

Address

Building: Jacques Monod

Location

2016-09-15 11:00:00 2016-09-15 00:00:00 Europe/Paris The zinc cluster proteins: a fungal family of transcriptional regulators with functions ranging from carbon metabolism to drug resistance Bernard TURCOTTE Dept of Medicine, McGill University Health Center, Montréal Québec (en année sabbatique dans l’Unité Génétique des Interactions Macromoléculaires) Abstract: Research in my lab focuses on a family of transcriptional regulators that are […] 25-28 Rue du Docteur Roux, Paris, France Alain Jacquier alain.jacquier@pasteur.fr

About

Bernard TURCOTTE
Dept of Medicine, McGill University Health Center, Montréal Québec
(en année sabbatique dans l’Unité Génétique des Interactions Macromoléculaires)

Abstract:
Research in my lab focuses on a family of transcriptional regulators that are called zinc cluster proteins. Members of this family are only found in fungi (or amoeba) and possess the well-conserved motif CysX2CysX6CysX5-12CysX2CysX6-8Cys. The cysteine residues bind to two zinc atoms, which coordinate folding of the domain involved in DNA recogition. The best known member of this family is probably Gal4, a transcriptional activator involved in galactose metabolism in budding yeast (Saccharomyces cerevisiae). Zinc cluster proteins function in a wide range of processes including metabolism, stress response, meiosis, and drug resistance. In budding yeast, we have characterized a number of zinc cluster proteins that are involved in controlling non fermentable carbon utilization through a complex regulatory network. More recently, we have extended our studies of this family of transcription factors to Candida glabrata, an important human fungal pathogen. Results show that a number of zinc cluster proteins modulate drug resistance in this pathogen

Location

Building: Jacques Monod
Address: 25-28 Rue du Docteur Roux, Paris, France

Published on: 13 Sep 2016

(function($) { /* * render_map * * This function will render a Google Map onto the selected jQuery element * * @type function * @date 8/11/2013 * @since 4.3.0 * * @param $el (jQuery element) * @return n/a */ function render_map( $el ) { var MY_MAPTYPE_ID = 'custom_style'; var featureOpts = [{"stylers":[{"hue":"#0088ff"}]}]; var styledMapOptions = { name: 'Custom Style' }; var customMapType = new google.maps.StyledMapType(featureOpts, styledMapOptions); // var var $markers = $el.find('.marker'); // vars var args = { zoom : 16, scrollwheel : false, center : new google.maps.LatLng(0, 0), mapTypeId : google.maps.MapTypeId.ROADMAP, mapTypeId : MY_MAPTYPE_ID }; // create map var map = new google.maps.Map( $el[0], args); map.mapTypes.set(MY_MAPTYPE_ID, customMapType); // add a markers reference map.markers = []; // add markers $markers.each(function(){ add_marker( $(this), map ); }); // center map center_map( map ); } /* * add_marker * * This function will add a marker to the selected Google Map * * @type function * @date 8/11/2013 * @since 4.3.0 * * @param $marker (jQuery element) * @param map (Google Map object) * @return n/a */ function add_marker( $marker, map ) { // var var latlng = new google.maps.LatLng( $marker.attr('data-lat'), $marker.attr('data-lng') ); //var image = 'https://research.pasteur.fr/wp-content/themes/biologyx2/images/logomap.png'; var myIcon = new google.maps.MarkerImage('https://research.pasteur.fr/wp-content/themes/biologyx2/images/map-pin.png', null, null, null, new google.maps.Size(32,32)); // create marker var marker = new google.maps.Marker({ position : latlng, map : map, icon : myIcon }); // add to array map.markers.push( marker ); // if marker contains HTML, add it to an infoWindow if( $marker.html() ) { // create info window var infowindow = new google.maps.InfoWindow({ content : $marker.html() }); // show info window when marker is clicked google.maps.event.addListener(marker, 'click', function() { infowindow.open( map, marker ); }); } } /* * center_map * * This function will center the map, showing all markers attached to this map * * @type function * @date 8/11/2013 * @since 4.3.0 * * @param map (Google Map object) * @return n/a */ function center_map( map ) { // vars var bounds = new google.maps.LatLngBounds(); // loop through all markers and create bounds $.each( map.markers, function( i, marker ){ var latlng = new google.maps.LatLng( marker.position.lat(), marker.position.lng() ); bounds.extend( latlng ); }); // only 1 marker? if( map.markers.length == 1 ) { // set center of map map.setCenter( bounds.getCenter() ); map.setZoom( 15 ); } else { // fit to bounds map.fitBounds( bounds ); } } /* * document ready * * This function will render each map when the document is ready (page has loaded) * * @type function * @date 8/11/2013 * @since 5.0.0 * * @param n/a * @return n/a */ $(document).ready(function(){ $('.acf-map').each(function(){ render_map( $(this) ); }); }); })(jQuery);