Timeline

Gérard Eberl
Head of Structure
12 Jun 2023
news

New publication – The parabrachial nucleus elicits a vigorous corticosterone feedback response to the pro-inflammatory cytokine IL-1beta

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26 May 2023
publication

The parabrachial nucleus elicits a vigorous corticosterone feedback response to the pro-inflammatory cytokine IL-1β.

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28 Mar 2023
program_project

Microbiotalogy

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10 Mar 2023
project

Labex GIL: Methanobrevibacter and Veillonella crosstalk with the intestinal mucosa in the context of health and inflammation

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04 Jul 2022
news

New publication – The neuropeptide VIP potentiates intestinal innate type 2 and type 3 immunity in response to feeding

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02 May 2022
publication

The neuropeptide VIP potentiates intestinal innate type 2 and type 3 immunity in response to feeding.

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22 Apr 2022
news

New publication – Bacterial sensing via neuronal Nod2 regulates appetite and body temperature

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16 Apr 2022
news

Gut microbes regulate appetite and body temperature

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15 Apr 2022
publication

Bacterial sensing via neuronal Nod2 regulates appetite and body temperature.

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01 Apr 2022
publication

TNF hampers intestinal tissue repair in colitis by restricting IL-22 bioavailability.

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21 Mar 2022
project

CoNCEPT – Clinical NeurosCiencE & PsychiaTry

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25 Oct 2021
event

PhD Thesis defence: The brain circuits controlling the immunosuppressive response to the inflammatory cytokine IL-1beta

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30 Mar 2021
publication

SARS-CoV-2 in severe COVID-19 induces a TGF-β-dominated chronic immune response that does not target itself.

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01 Jan 2021
publication

Interplay Between Microbiota, Toll-Like Receptors and Cytokines for the Maintenance of Epithelial Barrier Integrity.

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11 Dec 2020
publication

Effect of gut microbiota on depressive-like behaviors in mice is mediated by the endocannabinoid system.

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26 Oct 2020
publication

Metabolic regulation by PPARγ is required for IL-33-mediated activation of ILC2s in lung and adipose tissue.

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10 Aug 2020
news

Gut microbiota plays a role in brain function and mood regulation

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01 Jun 2020
publication

Beware of whom you live with: Your intestinal IgA may depend on it.

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01 Jun 2020
publication

Specific microbiota enhances intestinal IgA levels by inducing TGF-β in T follicular helper cells of Peyer’s patches in mice.

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17 Mar 2020
publication

Changes in Gut Microbiota by Chronic Stress Impair the Efficacy of Fluoxetine.

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29 Jan 2020
publication

Imprinting of the immune system by the microbiota early in life

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04 Nov 2019
publication

Excess calorie intake early in life increases susceptibility to colitis in adulthood

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04 Oct 2019
publication

A circadian clock is essential for homeostasis of group 3 innate lymphoid cells in the gut

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30 Sep 2019
publication

Characterization of the developmental landscape of murine RORγt+ iNKT cells.

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21 May 2019
publication

A Weaning Reaction to Microbiota Is Required for Resistance to Immunopathologies in the Adult.

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03 Apr 2019
publication

Innate lymphoid cells support regulatory T cells in the intestine through interleukin-2

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11 Mar 2019
publication

Multi-hit early life adversity affects gut microbiota, brain and behavior in a sex-dependent manner

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18 Feb 2019
publication

Inhibition of the dipeptidyl peptidase DPP4 (CD26) reveals IL-33-dependent eosinophil-mediated control of tumor growth

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15 Feb 2019
team

U1224 – Regulation of homeostasis and inflammation by lymphoid cells and microenvironment

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20 Nov 2018
news

How Listeria monocytogenes blocks intestinal villus invasion

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05 Nov 2018
publication

Peyer’s patch myeloid cells infection by Listeria signals through gp38+ stromal cells and locks intestinal villus invasion.

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02 Oct 2018
publication

The regenerating family member 3 β instigates IL-17A-mediated neutrophil recruitment downstream of NOD1/2 signalling for controlling colonisation resistance independently of microbiota community structure

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02 Oct 2018
publication

Blimp-1 Functions as a Molecular Switch to Prevent Inflammatory Activity in Foxp3RORγt Regulatory T Cells

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23 Aug 2018
publication

Innate Lymphoid Cells: 10 Years On.

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01 Aug 2018
publication

Antibiotic treatment-induced secondary IgA deficiency enhances susceptibility to Pseudomonas aeruginosa pneumonia.

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26 Jun 2018
publication

Effects of long-term intake of a yogurt fermented with Lactobacillus delbrueckii subsp. bulgaricus 2038 and Streptococcus thermophilus 1131 on mice

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28 May 2018
publication

Control of pathogens and microbiota by innate lymphoid cells

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17 Apr 2018
event

“Disruptive Discoveries for HIV, HCV and HBV Infections” by Raymond Schinazi – Virology & Immunology departments joint seminar

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07 Apr 2018
publication

The microbiota, a necessary element of immunity

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24 Mar 2018
event

Modeling the Mammalian Microbiota Host Superorganism – www.mam-2018.org

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16 Dec 2017
publication

Robustness in living organisms is homeostasis

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15 Dec 2017
publication

GAPs in early life facilitate immune tolerance

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08 Dec 2017
publication

Towards a General Theory of Immunity?

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25 Oct 2017
event

Herbert W. Virgin – “Control of immunity by the virome, and vice versa”

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07 Oct 2017
news

Microbes, Immunity and Metabolism international conference, November 15th-17th, 2017

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20 Sep 2017
event

Prof. Clifford WOOLF – “Peripheral neuro-immune interactions that amplify or suppress inflammation”

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04 Aug 2017
publication

Macrophages Induce Long-Term Trapping of γδ T Cells with Innate-like Properties within Secondary Lymphoid Organs in the Steady State

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06 Apr 2017
event

MIM 2017 “Microbes, Immunity and Metabolism international conference”

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10 Jan 2017
publication

CD34+ mesenchymal cells are a major component of the intestinal stem cells niche at homeostasis and after injury

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15 Dec 2016
publication

Notch regulates Th17 differentiation and controls trafficking of IL-17 and metabolic regulators within Th17 cells in a context-dependent manner

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09 Dec 2016
event

Marco Prinz seminar

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05 Oct 2016
publication

RORγt, a multitask nuclear receptor at mucosal surfaces

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30 Aug 2016
news

VIROLOGY AND IMMUNOLOGY JOINT SEMINAR

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17 Aug 2016
publication

The Spectrum and Regulatory Landscape of Intestinal Innate Lymphoid Cells Are Shaped by the Microbiome

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21 Jul 2016
event

Benoît Chassaing seminar

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13 Jul 2016
publication

Glial-cell-derived neuroregulators control type 3 innate lymphoid cells and gut defence

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11 Jul 2016
publication

Immunity by equilibrium

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08 Jul 2016
project

Adult neurogenesis and brain plasticity

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24 Jun 2016
publication

SLAM-associated protein favours the development of iNKT2 over iNKT17 cells

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21 Jun 2016
publication

Innate lymphoid cells in defense, immunopathology and immunotherapy

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03 Jun 2016
project

Think tank: Mucosal Immunology

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14 Apr 2016
publication

Infection-Mediated Priming of Phagocytes Protects against Lethal Secondary Aspergillus fumigatus Challenge

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14 Apr 2016
publication

Infection-Mediated Priming of Phagocytes Protects against Lethal Secondary Aspergillus fumigatus Challenge.

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11 Mar 2016
publication

IL-15-dependent balance between Foxp3 and RORγt expression impacts inflammatory bowel disease

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30 Nov 2015
publication

The potential role of microbiota in major psychiatric disorders: Mechanisms, preclinical data, gastro-intestinal comorbidities and therapeutic options

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05 Nov 2015
publication

Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota

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19 Oct 2015
publication

ILC3s protect intestinal stem cells from chemotherapy

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08 Sep 2015
program_project

Major Federating Program Microbes & Brain

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29 Jul 2015
publication

IL-7/IL-7 Receptor Signaling Differentially Affects Effector CD4+ T Cell Subsets Involved in Experimental Autoimmune Encephalomyelitis

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17 Jul 2015
project

When Gut Bacteria Changes Brain Functions

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09 Jul 2015
publication

The microbiota regulates type 2 immunity through RORγt⁺ T cells

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01 Jul 2015
project

Symbiotic microbiota and the development and regulation of the immune system

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01 Jul 2015
project

The role of Intestinal lymphoid cells (ILCs) in defense and physiology

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01 Jul 2015
publication

The Gut Microbiota Regulates Intestinal CD4 T Cells Expressing RORγt and Controls Metabolic Disease

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21 May 2015
publication

Innate lymphoid cells. Innate lymphoid cells: a new paradigm in immunology.

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11 May 2015
team

Microenvironment and Immunity

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23 Apr 2015
publication

Group 3 innate lymphoid cells mediate intestinal selection of commensal bacteria-specific CD4⁺ T cells

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08 Apr 2015
publication

Addressing the experimental variability associated with the microbiota

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20 Jan 2015
publication

Liver-resident macrophage necroptosis orchestrates type 1 microbicidal inflammation and type-2-mediated tissue repair during bacterial infection.

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19 Jan 2015
publication

Commensal microbiota influence systemic autoimmune responses

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17 Jan 2015
publication

An optimized protocol for isolating lymphoid stromal cells from the intestinal lamina propria

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01 Jan 2015
publication

The brave new world of innate lymphoid cells

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18 Sep 2014
publication

Innate lymphoid cells in inflammation and immunity

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15 Sep 2014
department

Immunology

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02 Jun 2014
publication

The biology of bacterial peptidoglycans and their impact on host immunity and physiology

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07 May 2014
publication

TLR-induced cytokines promote effective proinflammatory natural Th17 cell responses

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17 Apr 2014
publication

Segmented filamentous bacterium uses secondary and tertiary lymphoid tissues to induce gut IgA and specific T helper 17 cell responses

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26 Mar 2014
publication

Development and regulation of RORγt(+) innate lymphoid cells

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19 Mar 2014
publication

Immunology: A is for immunity

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19 Mar 2014
publication

Regulatory T cells promote a protective Th17-associated immune response to intestinal bacterial infection with C. rodentium

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26 Feb 2014
publication

Activation of Type 3 innate lymphoid cells and interleukin 22 secretion in the lungs during Streptococcus pneumoniae infection

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01 Dec 2013
publication

Nonredundant function of soluble LTα3 produced by innate lymphoid cells in intestinal homeostasis

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22 Nov 2013
publication

The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide

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22 Nov 2013
publication

M1 macrophages act as LTβR-independent lymphoid tissue inducer cells during atherosclerosis-related lymphoid neogenesis

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05 Aug 2013
publication

Origin, trafficking, and intraepithelial fate of gut-tropic T cells

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12 Jun 2013
publication

Penicillin resistance compromises Nod1-dependent proinflammatory activity and virulence fitness of neisseria meningitidis.

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22 May 2013
publication

Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria

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17 Apr 2013
publication

Interleukin-22 reduces lung inflammation during influenza A virus infection and protects against secondary bacterial infection

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07 Feb 2013
publication

Animals in a bacterial world, a new imperative for the life sciences

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29 Jul 2012
publication

Lineage tracing and genetic ablation of ADAM12(+) perivascular cells identify a major source of profibrotic cells during acute tissue injury

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01 Jul 2012
publication

IL-23 induces spondyloarthropathy by acting on ROR-γt+ CD3+CD4-CD8- entheseal resident T cells

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21 Jun 2012
publication

CD4+ T cells rely on a cytokine gradient to control intracellular pathogens beyond sites of antigen presentation

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20 Apr 2012
publication

Development and function of intestinal innate lymphoid cells

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19 Mar 2012
publication

Notch, Id2, and RORγt sequentially orchestrate the fetal development of lymphoid tissue inducer cells

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08 Mar 2012
publication

Stat3 and Gfi-1 transcription factors control Th17 cell immunosuppressive activity via the regulation of ectonucleotidase expression

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01 Mar 2012
publication

The development of LTi cells

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01 Jan 2012
publication

Development and evolution of RORγt+ cells in a microbe’s world

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16 Dec 2011
publication

The dialog between microbiota and the immune system: shaping the partners through development and evolution

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10 Nov 2011
publication

NOD mice contain an elevated frequency of iNKT17 cells that exacerbate diabetes

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16 Aug 2011
publication

IL-1 and IL-23 mediate early IL-17A production in pulmonary inflammation leading to late fibrosis

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21 Feb 2011
publication

Intestinal microbiota, evolution of the immune system and the bad reputation of pro-inflammatory immunity

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01 Feb 2011
publication

Lymphotoxin-β receptor-independent development of intestinal IL-22-producing NKp46+ innate lymphoid cells

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23 Dec 2010
publication

Critical role of the calpain/calpastatin balance in acute allograft rejection

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22 Dec 2010
publication

Restricted microbiota and absence of cognate TCR antigen leads to an unbalanced generation of Th17 cells

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20 Dec 2010
publication

Microbiota-induced tertiary lymphoid tissues aggravate inflammatory disease in the absence of RORgamma t and LTi cells

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21 Oct 2010
publication

Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling

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24 Jun 2010
publication

Bacteria and MAMP-induced morphogenesis of the immune system.

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04 Jun 2010
publication

Chronic rejection triggers the development of an aggressive intragraft immune response through recapitulation of lymphoid organogenesis

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05 May 2010
publication

A new vision of immunity: homeostasis of the superorganism

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29 Apr 2010
publication

Immunology: Close encounters of the second type

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08 Feb 2010
publication

IL-7 and IL-15 independently program the differentiation of intestinal CD3-NKp46+ cell subsets from Id2-dependent precursors

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20 Jan 2010
publication

Th17 cells are the dominant T cell subtype primed by Shigella flexneri mediating protective immunity

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16 Dec 2009
publication

Opening the crypt: current facts and hypotheses on the function of cryptopatches

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16 Oct 2009
publication

The key role of segmented filamentous bacteria in the coordinated maturation of gut helper T cell responses

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07 Oct 2009
publication

Nonfunctional regulatory T cells and defective control of Th2 cytokine production in natural scurfy mutant mice

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09 Sep 2009
publication

The development of intestinal lymphoid tissues at the interface of self and microbiota

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08 Sep 2009
publication

The nuclear receptor PPAR gamma selectively inhibits Th17 differentiation in a T cell-intrinsic fashion and suppresses CNS autoimmunity

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08 Jul 2009
publication

Skin and peripheral lymph node invariant NKT cells are mainly retinoic acid receptor-related orphan receptor (gamma)t+ and respond preferentially under inflammatory conditions

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01 May 2009
publication

Inflammation recapitulates the ontogeny of lymphoid stromal cells

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21 Jan 2009
publication

Characterization of the thymic IL-7 niche in vivo

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11 Dec 2008
publication

Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense

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04 Dec 2008
publication

Critical role of ROR-γt in a new thymic pathway leading to IL-17-producing invariant NKT cell differentiation

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01 Dec 2008
publication

DC activated via dectin-1 convert Treg into IL-17 producers

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26 May 2008
publication

In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORgamma t+ T cells

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07 Sep 2007
publication

From induced to programmed lymphoid tissues: the long road to preempt pathogens

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23 Apr 2007
publication

Mature natural killer cell and lymphoid tissue-inducing cell development requires Id2-mediated suppression of E protein activity

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16 Apr 2007
publication

BAC to immunology–bacterial artificial chromosome-mediated transgenesis for targeting of immune cells

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02 Jan 2007
publication

Selective depletion of Foxp3+ regulatory T cells induces a scurfy-like disease

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01 May 2005
publication

Inducible lymphoid tissues in the adult gut: recapitulation of a fetal developmental pathway?

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