Timeline

Sébastien Brier
Research Engineer
27 Jun 2019
publication

Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments

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21 Jun 2019
publication

Post-translational acylation controls the folding and functions of the CyaA RTX toxin

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23 May 2019
publication

Dynamics of a type 2 secretion system pseudopilus unraveled by complementary approaches

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18 Nov 2018
publication

Translocation and calmodulin-activation of the adenylate cyclase toxin (CyaA) of Bordetella pertussis

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28 Jun 2018
team

Biological NMR Technological Platform

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29 Dec 2017
publication

Calmodulin fishing with a structurally disordered bait triggers CyaA catalysis

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24 Nov 2017
publication

Characterization of epitope specificities of reference antibodies used for the quantification of the birch pollen allergen Bet v 1

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14 Nov 2017
publication

Structural disorder and induced folding within two cereal, ABA stress and ripening (ASR) proteins

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28 Sep 2017
publication

Structural Characterization of Whirlin Reveals an Unexpected and Dynamic Supramodule Conformation of Its PDZ Tandem

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21 May 2017
publication

Prepore Stability Controls Productive Folding of the BAM-independent Multimeric Outer Membrane Secretin PulD.

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19 Apr 2017
publication

Structure and allosteric inhibition of excitatory amino acid transporter 1

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27 Jan 2017
event

HDX-MS/NMR DAY

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30 Nov 2016
publication

Prepore Stability Controls Productive Folding of the BAM-independent Multimeric Outer Membrane Secretin PulD

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01 Sep 2016
publication

Proteomics for Allergy: from Proteins to the Patients

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13 Jul 2016
publication

MEMHDX: an interactive tool to expedite the statistical validation and visualization of large HDX-MS datasets

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23 Jun 2016
software

MEMHDX – Mixed Effects Models for HDX experiments

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22 Apr 2016
publication

Molecular Basis of Ligand-Dependent Regulation of NadR, the Transcriptional Repressor of Meningococcal Virulence Factor NadA

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18 Nov 2015
project

Molecular crowding

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08 Oct 2015
project

In solution conformation of the SigmaS subunit of RNA polymerase

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16 Sep 2015
publication

Structural models of intrinsically disordered and calcium-bound folded states of a protein adapted for secretion

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17 Aug 2015
project

CyaA secretion, folding and translocation across membrane

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21 Jul 2015
project

Development of a new statistical tool for the analysis of large HDX-MS data sets

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11 May 2015
team

Mass Spectrometry for Biology (UTechS MSBio)

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20 Feb 2015
publication

Neisseria meningitis GNA1030 is a ubiquinone-8 binding protein

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17 Feb 2015
team

Proteomics

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26 Dec 2013
publication

Two cross-reactive monoclonal antibodies recognize overlapping epitopes on Neisseria meningitidis factor H binding protein but have different functional properties

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08 Feb 2013
publication

Defining a protective epitope on factor H binding protein, a key meningococcal virulence factor and vaccine antigen

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10 Dec 2012
publication

Transcriptional regulation of the nadA gene in Neisseria meningitidis impacts the prediction of coverage of a multicomponent meningococcal serogroup B vaccine

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15 Aug 2012
publication

Structural insight into the mechanism of DNA-binding attenuation of the Neisserial adhesin repressor NadR by the small natural ligand 4-hydroxyphenylacetic acid

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30 Jun 2010
publication

Mapping surface accessibility of the C1r/C1s tetramer by chemical modification and mass spectrometry provides new insights into assembly of the human C1 complex

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01 Apr 2009
publication

Aspartic proteinases in Antarctic fish

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01 Jan 2008
publication

Hydrogen exchange mass spectrometry: principles and capabilities

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01 Nov 2007
publication

Purification and characterization of pepsins A1 and A2 from the Antarctic rock cod Trematomus bernacchii

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27 Feb 2007
publication

The Abl SH2-kinase linker naturally adopts a conformation competent for SH3 domain binding

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01 Dec 2006
publication

The marine natural product adociasulfate-2 as a tool to identify the MT-binding region of kinesins

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15 May 2006
publication

Molecular dissection of the inhibitor binding pocket of mitotic kinesin Eg5 reveals mutants that confer resistance to antimitotic agents

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01 Jan 2006
publication

Use of hydrogen/deuterium exchange mass spectrometry and mutagenesis as a tool to identify the binding region of inhibitors targeting the human mitotic kinesin Eg5

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19 Oct 2004
publication

Identification of the protein binding region of S-trityl-L-cysteine, a new potent inhibitor of the mitotic kinesin Eg5

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