Ligne de temps
Sébastien Brier
Ingénieur(e) de Recherche
02 févr. 2023
publication
Structure and dynamic association of an assembly platform subcomplex of the bacterial type II secretion system.
Lire plus01 févr. 2023
news
Bacterial pathogenicity: improving understanding of an essential process – molecule secretion
Lire plus11 sept. 2022
project
Energir: Comprendre les mécanismes moléculaires d’acquisition du fer chez les bactéries à Gram-négatif, par une approche intégrative
Lire plus09 août 2022
publication
Dynamics and structural changes of calmodulin upon interaction with the antagonist calmidazolium.
Lire plus16 mars 2022
01 janv. 2022
publication
Development of a highly specific and sensitive VHH-based sandwich immunoassay for the detection of the SARS-CoV-2 nucleoprotein.
Lire plus01 mai 2021
publication
Characterization of a highly neutralizing single monoclonal antibody to botulinum neurotoxin type A.
Lire plus01 mai 2021
publication
A High-Affinity Calmodulin-Binding Site in the CyaA Toxin Translocation Domain is Essential for Invasion of Eukaryotic Cells.
Lire plus01 janv. 2020
publication
Hydrogen/Deuterium Exchange Mass Spectrometry for the Structural Analysis of Detergent-Solubilized Membrane Proteins.
Lire plus27 juin 2019
publication
Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments
Lire plus21 juin 2019
publication
Post-translational acylation controls the folding and functions of the CyaA RTX toxin.
Lire plus23 mai 2019
publication
Dynamics of a type 2 secretion system pseudopilus unraveled by complementary approaches
Lire plus01 nov. 2018
publication
Translocation and calmodulin-activation of the adenylate cyclase toxin (CyaA) of Bordetella pertussis.
Lire plus28 juin 2018
24 nov. 2017
publication
Characterization of epitope specificities of reference antibodies used for the quantification of the birch pollen allergen Bet v 1
Lire plus14 nov. 2017
publication
Structural disorder and induced folding within two cereal, ABA stress and ripening (ASR) proteins
Lire plus28 sept. 2017
publication
Structural Characterization of Whirlin Reveals an Unexpected and Dynamic Supramodule Conformation of Its PDZ Tandem
Lire plus21 mai 2017
publication
Prepore Stability Controls Productive Folding of the BAM-independent Multimeric Outer Membrane Secretin PulD.
Lire plus19 avr. 2017
27 janv. 2017
06 janv. 2017
publication
Prepore Stability Controls Productive Folding of the BAM-independent Multimeric Outer Membrane Secretin PulD.
Lire plus01 janv. 2017
publication
Calmodulin fishing with a structurally disordered bait triggers CyaA catalysis.
Lire plus01 sept. 2016
13 juil. 2016
publication
MEMHDX: an interactive tool to expedite the statistical validation and visualization of large HDX-MS datasets.
Lire plus23 juin 2016
22 avr. 2016
publication
Molecular Basis of Ligand-Dependent Regulation of NadR, the Transcriptional Repressor of Meningococcal Virulence Factor NadA
Lire plus18 nov. 2015
16 sept. 2015
publication
Structural models of intrinsically disordered and calcium-bound folded states of a protein adapted for secretion.
Lire plus17 août 2015
21 juil. 2015
07 juil. 2015
11 mai 2015
20 févr. 2015
26 déc. 2013
publication
Two cross-reactive monoclonal antibodies recognize overlapping epitopes on Neisseria meningitidis factor H binding protein but have different functional properties
Lire plus08 févr. 2013
publication
Defining a protective epitope on factor H binding protein, a key meningococcal virulence factor and vaccine antigen
Lire plus10 déc. 2012
publication
Transcriptional regulation of the nadA gene in Neisseria meningitidis impacts the prediction of coverage of a multicomponent meningococcal serogroup B vaccine
Lire plus15 août 2012
publication
Structural insight into the mechanism of DNA-binding attenuation of the Neisserial adhesin repressor NadR by the small natural ligand 4-hydroxyphenylacetic acid
Lire plus30 juin 2010
publication
Mapping surface accessibility of the C1r/C1s tetramer by chemical modification and mass spectrometry provides new insights into assembly of the human C1 complex
Lire plus01 avr. 2009
01 janv. 2008
01 nov. 2007
publication
Purification and characterization of pepsins A1 and A2 from the Antarctic rock cod Trematomus bernacchii
Lire plus27 févr. 2007
publication
The Abl SH2-kinase linker naturally adopts a conformation competent for SH3 domain binding
Lire plus01 déc. 2006
publication
The marine natural product adociasulfate-2 as a tool to identify the MT-binding region of kinesins
Lire plus15 mai 2006
publication
Molecular dissection of the inhibitor binding pocket of mitotic kinesin Eg5 reveals mutants that confer resistance to antimitotic agents
Lire plus01 janv. 2006
publication
Use of hydrogen/deuterium exchange mass spectrometry and mutagenesis as a tool to identify the binding region of inhibitors targeting the human mitotic kinesin Eg5
Lire plus19 oct. 2004
publication