Timeline

Vincent Bondet
Research Engineer
02 Sep 2024
publication

SARS-CoV-2 brainstem encephalitis in human inherited DBR1 deficiency.

Read more
28 Aug 2024
publication

Hereditary C1q Deficiency is Associated with Type 1 Interferon-Pathway Activation and a High Risk of Central Nervous System Inflammation.

Read more
15 Nov 2023
news

New publication – Tuberculosis alters immune-metabolic pathways resulting in perturbed IL-1 responses

Read more
09 Aug 2023
publication

Dissecting human population variation in single-cell responses to SARS-CoV-2

Read more
01 Aug 2023
publication

Heterogeneity and functions of the 13 IFN-α subtypes – lucky for some?

Read more
12 May 2023
publication

JAK Inhibition in Aicardi-Goutières Syndrome: a Monocentric Multidisciplinary Real-World Approach Study.

Read more
01 Apr 2023
publication

Central Role of Macrophages and Nucleic Acid Release in Myasthenia Gravis Thymus.

Read more
17 Jan 2023
publication

Inactive disease in patients with lupus is linked to autoantibodies to type I interferons that normalize blood IFNα and B cell subsets.

Read more
05 Dec 2022
publication

Juvenile Neuropsychiatric Systemic Lupus Erythematosus: Identification of Novel Central Neuroinflammation Biomarkers.

Read more
25 Nov 2022
publication

Defective activation and regulation of type I interferon immunity is associated with increasing COVID-19 severity.

Read more
15 Nov 2022
publication

Enhanced TLR3 responsiveness in hepatitis C virus resistant women from the Irish anti-D cohort.

Read more
28 Jun 2022
publication

Early IFNβ secretion determines variable downstream IL-12p70 responses upon TLR4 activation.

Read more
20 Jun 2022
publication

Variability of Primary Sjögren’s Syndrome Is Driven by Interferon-α and Interferon-α Blood Levels Are Associated With the Class II HLA-DQ Locus.

Read more
09 Jun 2022
publication

Interferon-α-mediated therapeutic resistance in early rheumatoid arthritis implicates epigenetic reprogramming.

Read more
18 Apr 2022
publication

CXCR3 Expression Pattern on CD4+ T Cells and IP-10 Levels with Regard to the HIV-1 Reservoir in the Gut-Associated Lymphatic Tissue.

Read more
31 Mar 2022
publication

Activation of NLRP3 Inflammasome in the Skin of Patients with Systemic and Cutaneous Lupus Erythematosus.

Read more
28 Mar 2022
news

New publication – Defects in mucosal immunity and nasopharyngeal dysbiosis in HSC transplanted SCID patients with IL2RG/JAK3 deficiency

Read more
23 Feb 2022
publication

Efficacy and tolerance of corticosteroids and methotrexate in patients with juvenile dermatomyositis: a retrospective cohort study.

Read more
14 Feb 2022
publication

Defects in mucosal immunity and nasopharyngeal dysbiosis in HSC transplanted SCID patients with IL2RG/JAK3 deficiency.

Read more
01 Feb 2022
publication

Primary immune responses are negatively impacted by persistent herpesvirus infections in older people: results from an observational study on healthy subjects and a vaccination trial on subjects aged more than 70 years old.

Read more
01 Jan 2022
publication

Tuberculosis alters immune-metabolic pathways resulting in perturbed IL-1 responses.

Read more
01 Sep 2021
publication

Distinct systemic and mucosal immune responses during acute SARS-CoV-2 infection.

Read more
23 Aug 2021
publication

Onset and Relapse of Juvenile Dermatomyositis Following Asymptomatic SARS-CoV-2 Infection.

Read more
01 Aug 2021
publication

Differential levels of IFNα subtypes in autoimmunity and viral infection.

Read more
04 Jun 2021
publication

Regulation of the acetylcholine/α7nAChR anti-inflammatory pathway in COVID-19 patients.

Read more
01 May 2021
publication

HIV DNA reservoir and elevated PD-1 expression of CD4 T-cell subsets particularly persist in the terminal ileum of HIV-positive patients despite cART.

Read more
01 Apr 2021
publication

Differential Expression of Interferon-Alpha Protein Provides Clues to Tissue Specificity Across Type I Interferonopathies.

Read more
12 Feb 2021
publication

JAK inhibitors are effective in a subset of patients with juvenile dermatomyositis: a monocentric retrospective study.

Read more
01 Feb 2021
publication

Overview of STING-Associated Vasculopathy with Onset in Infancy (SAVI) Among 21 Patients.

Read more
04 Jan 2021
publication

TLR3 controls constitutive IFN-β antiviral immunity in human fibroblasts and cortical neurons.

Read more
01 Jan 2021
publication

Constitutive IFNα Protein Production in Bats.

Read more
01 Jan 2021
publication

Altered Immune Phenotypes and HLA-DQB1 Gene Variation in Multiple Sclerosis Patients Failing Interferon β Treatment.

Read more
02 Nov 2020
publication

Mutations in COPA lead to abnormal trafficking of STING to the Golgi and interferon signaling.

Read more
24 Sep 2020
publication

Dysregulation of tryptophan catabolism at the host-skin microbiota interface in Hidradenitis Suppurativa.

Read more
19 Sep 2020
publication

Absence of Neuronal Autoantibodies in Neuropsychiatric Systemic Lupus Erythematosus.

Read more
13 Jul 2020
publication

Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients.

Read more
02 Jul 2020
team

Translational Immunology

Read more
22 Jun 2020
publication

Three Copies of Four Interferon Receptor Genes Underlie a Mild Type I Interferonopathy in Down Syndrome.

Read more
19 Jun 2020
publication

Catatonia in a patient with Aicardi-Goutières syndrome efficiently treated with immunoadsorption.

Read more
05 Jun 2020
publication

Innate immune stimulation of whole blood reveals IFN-1 hyper-responsiveness in type 1 diabetes.

Read more
05 Mar 2020
publication

The proteome of neutrophils in sickle cell disease reveals an unexpected activation of interferon alpha signaling pathway

Read more
01 Jan 2020
publication

Decreased Type I Interferon Production by Plasmacytoid Dendritic Cells Contributes to Severe Dengue.

Read more
13 Dec 2019
publication

Severe type I interferonopathy and unrestrained interferon signaling due to a homozygous germline mutation in

Read more
26 Nov 2019
publication

Cardiac valve involvement in -related type I interferonopathy

Read more
26 Nov 2019
publication

PSMB10, the last immunoproteasome gene missing for PRAAS

Read more
22 Nov 2019
publication

Anti-MDA5 juvenile idiopathic inflammatory myopathy: a specific subgroup defined by differentially enhanced interferon-α signalling

Read more
30 Oct 2019
publication

Use of ruxolitinib in COPA syndrome manifesting as life-threatening alveolar haemorrhage

Read more
30 Oct 2019
publication

Inhibition of IFNα secretion in cells from patients with juvenile dermatomyositis under TBK1 inhibitor treatment revealed by single-molecular assay technology

Read more
05 Oct 2019
publication

Risk factors associated with myasthenia gravis in thymoma patients: The potential role of thymic germinal centers

Read more
05 Sep 2019
publication

Circulating interferon-α measured with a highly sensitive assay as a biomarker for juvenile inflammatory myositis activity

Read more
22 Aug 2019
publication

Plasma Type I IFN Protein Concentrations in Human Tuberculosis

Read more
10 Jul 2019
publication

Control of TLR7-mediated type I IFN signaling in pDCs through CXCR4 engagement-A new target for lupus treatment

Read more
14 Jun 2019
publication

Type I interferon in patients with systemic autoimmune rheumatic disease is associated with haematological abnormalities and specific autoantibody profiles

Read more
22 May 2019
publication

IP-10 contributes to the inhibition of mycobacterial growth in an ex vivo whole blood assay

Read more
08 Apr 2019
publication

Delineating the healthy human skin UV response and early induction of interferon pathway in cutaneous lupus erythematosus

Read more
07 Mar 2019
publication

Interferon signature in patients with STAT1 gain-of-function mutation is epigenetically determined

Read more
18 Feb 2019
publication

Inhibition of the dipeptidyl peptidase DPP4 (CD26) reveals IL-33-dependent eosinophil-mediated control of tumor growth

Read more
04 Jan 2019
team

Production and Purification of Recombinant Proteins Technological Platform

Read more
06 Dec 2018
publication

Reverse-Transcriptase Inhibitors in the Aicardi–Goutières Syndrome

Read more
01 Nov 2018
publication

A child with severe juvenile dermatomyositis treated with ruxolitinib

Read more
03 Oct 2018
publication

Efficacy of JAK1/2 inhibition in the treatment of chilblain lupus due to TREX1 deficiency

Read more
07 Sep 2018
publication

First description of agonist and antagonist IP-10 in urine of patients with active TB

Read more
05 Jul 2018
publication

Interplay of DDP4 and IP-10 as a Potential Mechanism for Cell Recruitment to Tuberculosis Lesions

Read more
14 Jun 2018
publication

Development and Validation of an Ultrasensitive Single Molecule Array Digital Enzyme-linked Immunosorbent Assay for Human Interferon-α

Read more
01 Jun 2018
publication

JAK inhibitor improves type I interferon induced damage: proof of concept in dermatomyositis

Read more
01 Jun 2018
publication

Comment on: ‘Aberrant tRNA processing causes an autoinflammatory syndrome responsive to TNF inhibitors’ by Giannelou : mutations in result in a constitutive activation of type I interferon signalling

Read more
19 Dec 2017
publication

Type I interferon-mediated autoinflammation due to DNase II deficiency

Read more
20 Apr 2017
publication

TBK1/IKKE blockade inhibits mutant STING mediated inflammatory response in patient cells

Read more
18 Apr 2017
publication

Detection of interferon alpha protein reveals differential levels and cellular sources in disease

Read more
10 Sep 2015
project

Biomarker discovery and viral disease pathogenesis

Read more
10 Sep 2015
project

Functional immune response to Mycobacteria tuberculosis derived antigen

Read more
11 Oct 2013
publication

Structural and functional characterization of an orphan ATP-binding cassette ATPase involved in manganese utilization and tolerance in Leptospira spp

Read more
27 Jul 2007
publication

The crystal structure of M. leprae ML2640c defines a large family of putative S-adenosylmethionine-dependent methyltransferases in mycobacteria

Read more