Ligne de temps

Vincent Bondet
Ingénieur(e) de Recherche
17 nov. 2024
publication

Cytokine Autoantibodies Alter Gene Expression Profiles of Healthy Donors.

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12 nov. 2024
publication

Increased mortality in diffuse systemic sclerosis patients with high circulating IFNα levels.

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11 oct. 2024
publication

From Gut to Blood: Redistribution of Zonulin in People Living with HIV.

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02 sept. 2024
publication

SARS-CoV-2 brainstem encephalitis in human inherited DBR1 deficiency.

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28 août 2024
publication

Hereditary C1q Deficiency is Associated with Type 1 Interferon-Pathway Activation and a High Risk of Central Nervous System Inflammation.

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15 nov. 2023
news

New publication – Tuberculosis alters immune-metabolic pathways resulting in perturbed IL-1 responses

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09 août 2023
publication

Dissecting human population variation in single-cell responses to SARS-CoV-2

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01 août 2023
publication

Heterogeneity and functions of the 13 IFN-α subtypes – lucky for some?

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12 mai 2023
publication

JAK Inhibition in Aicardi-Goutières Syndrome: a Monocentric Multidisciplinary Real-World Approach Study.

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01 avr. 2023
publication

Central Role of Macrophages and Nucleic Acid Release in Myasthenia Gravis Thymus.

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17 janv. 2023
publication

Inactive disease in patients with lupus is linked to autoantibodies to type I interferons that normalize blood IFNα and B cell subsets.

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05 déc. 2022
publication

Juvenile Neuropsychiatric Systemic Lupus Erythematosus: Identification of Novel Central Neuroinflammation Biomarkers.

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25 nov. 2022
publication

Defective activation and regulation of type I interferon immunity is associated with increasing COVID-19 severity.

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15 nov. 2022
publication

Enhanced TLR3 responsiveness in hepatitis C virus resistant women from the Irish anti-D cohort.

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28 juin 2022
publication

Early IFNβ secretion determines variable downstream IL-12p70 responses upon TLR4 activation.

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20 juin 2022
publication

Variability of Primary Sjögren’s Syndrome Is Driven by Interferon-α and Interferon-α Blood Levels Are Associated With the Class II HLA-DQ Locus.

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09 juin 2022
publication

Interferon-α-mediated therapeutic resistance in early rheumatoid arthritis implicates epigenetic reprogramming.

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18 avr. 2022
publication

CXCR3 Expression Pattern on CD4+ T Cells and IP-10 Levels with Regard to the HIV-1 Reservoir in the Gut-Associated Lymphatic Tissue.

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31 mars 2022
publication

Activation of NLRP3 Inflammasome in the Skin of Patients with Systemic and Cutaneous Lupus Erythematosus.

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28 mars 2022
news

New publication – Defects in mucosal immunity and nasopharyngeal dysbiosis in HSC transplanted SCID patients with IL2RG/JAK3 deficiency

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23 févr. 2022
publication

Efficacy and tolerance of corticosteroids and methotrexate in patients with juvenile dermatomyositis: a retrospective cohort study.

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14 févr. 2022
publication

Defects in mucosal immunity and nasopharyngeal dysbiosis in HSC transplanted SCID patients with IL2RG/JAK3 deficiency.

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01 févr. 2022
publication

Primary immune responses are negatively impacted by persistent herpesvirus infections in older people: results from an observational study on healthy subjects and a vaccination trial on subjects aged more than 70 years old.

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01 janv. 2022
publication

Tuberculosis alters immune-metabolic pathways resulting in perturbed IL-1 responses.

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01 sept. 2021
publication

Distinct systemic and mucosal immune responses during acute SARS-CoV-2 infection.

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23 août 2021
publication

Onset and Relapse of Juvenile Dermatomyositis Following Asymptomatic SARS-CoV-2 Infection.

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01 août 2021
publication

Differential levels of IFNα subtypes in autoimmunity and viral infection.

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04 juin 2021
publication

Regulation of the acetylcholine/α7nAChR anti-inflammatory pathway in COVID-19 patients.

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01 mai 2021
publication

HIV DNA reservoir and elevated PD-1 expression of CD4 T-cell subsets particularly persist in the terminal ileum of HIV-positive patients despite cART.

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01 avr. 2021
publication

Differential Expression of Interferon-Alpha Protein Provides Clues to Tissue Specificity Across Type I Interferonopathies.

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12 févr. 2021
publication

JAK inhibitors are effective in a subset of patients with juvenile dermatomyositis: a monocentric retrospective study.

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01 févr. 2021
publication

Overview of STING-Associated Vasculopathy with Onset in Infancy (SAVI) Among 21 Patients.

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04 janv. 2021
publication

TLR3 controls constitutive IFN-β antiviral immunity in human fibroblasts and cortical neurons.

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01 janv. 2021
publication

Altered Immune Phenotypes and HLA-DQB1 Gene Variation in Multiple Sclerosis Patients Failing Interferon β Treatment.

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01 janv. 2021
publication

Constitutive IFNα Protein Production in Bats.

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02 nov. 2020
publication

Mutations in COPA lead to abnormal trafficking of STING to the Golgi and interferon signaling.

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24 sept. 2020
publication

Dysregulation of tryptophan catabolism at the host-skin microbiota interface in Hidradenitis Suppurativa.

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19 sept. 2020
publication

Absence of Neuronal Autoantibodies in Neuropsychiatric Systemic Lupus Erythematosus.

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13 juil. 2020
publication

Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients.

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02 juil. 2020
team

Immunologie Translationnelle

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22 juin 2020
publication

Three Copies of Four Interferon Receptor Genes Underlie a Mild Type I Interferonopathy in Down Syndrome.

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19 juin 2020
publication

Catatonia in a patient with Aicardi-Goutières syndrome efficiently treated with immunoadsorption.

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05 juin 2020
publication

Innate immune stimulation of whole blood reveals IFN-1 hyper-responsiveness in type 1 diabetes.

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05 mars 2020
publication

The proteome of neutrophils in sickle cell disease reveals an unexpected activation of interferon alpha signaling pathway

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01 janv. 2020
publication

Decreased Type I Interferon Production by Plasmacytoid Dendritic Cells Contributes to Severe Dengue.

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13 déc. 2019
publication

Severe type I interferonopathy and unrestrained interferon signaling due to a homozygous germline mutation in

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26 nov. 2019
publication

Cardiac valve involvement in -related type I interferonopathy

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26 nov. 2019
publication

PSMB10, the last immunoproteasome gene missing for PRAAS

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22 nov. 2019
publication

Anti-MDA5 juvenile idiopathic inflammatory myopathy: a specific subgroup defined by differentially enhanced interferon-α signalling

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30 oct. 2019
publication

Use of ruxolitinib in COPA syndrome manifesting as life-threatening alveolar haemorrhage

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30 oct. 2019
publication

Inhibition of IFNα secretion in cells from patients with juvenile dermatomyositis under TBK1 inhibitor treatment revealed by single-molecular assay technology

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05 oct. 2019
publication

Risk factors associated with myasthenia gravis in thymoma patients: The potential role of thymic germinal centers

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05 sept. 2019
publication

Circulating interferon-α measured with a highly sensitive assay as a biomarker for juvenile inflammatory myositis activity

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22 août 2019
publication

Plasma Type I IFN Protein Concentrations in Human Tuberculosis

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10 juil. 2019
publication

Control of TLR7-mediated type I IFN signaling in pDCs through CXCR4 engagement-A new target for lupus treatment

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14 juin 2019
publication

Type I interferon in patients with systemic autoimmune rheumatic disease is associated with haematological abnormalities and specific autoantibody profiles

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22 mai 2019
publication

IP-10 contributes to the inhibition of mycobacterial growth in an ex vivo whole blood assay

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08 avr. 2019
publication

Delineating the healthy human skin UV response and early induction of interferon pathway in cutaneous lupus erythematosus

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07 mars 2019
publication

Interferon signature in patients with STAT1 gain-of-function mutation is epigenetically determined

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18 févr. 2019
publication

Inhibition of the dipeptidyl peptidase DPP4 (CD26) reveals IL-33-dependent eosinophil-mediated control of tumor growth

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04 janv. 2019
team

Plate-Forme Technologique Production et Purification de Protéines Recombinantes

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06 déc. 2018
publication

Reverse-Transcriptase Inhibitors in the Aicardi–Goutières Syndrome

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01 nov. 2018
publication

A child with severe juvenile dermatomyositis treated with ruxolitinib

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03 oct. 2018
publication

Efficacy of JAK1/2 inhibition in the treatment of chilblain lupus due to TREX1 deficiency

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07 sept. 2018
publication

First description of agonist and antagonist IP-10 in urine of patients with active TB

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05 juil. 2018
publication

Interplay of DDP4 and IP-10 as a Potential Mechanism for Cell Recruitment to Tuberculosis Lesions

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14 juin 2018
publication

Development and Validation of an Ultrasensitive Single Molecule Array Digital Enzyme-linked Immunosorbent Assay for Human Interferon-α

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01 juin 2018
publication

JAK inhibitor improves type I interferon induced damage: proof of concept in dermatomyositis

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01 juin 2018
publication

Comment on: ‘Aberrant tRNA processing causes an autoinflammatory syndrome responsive to TNF inhibitors’ by Giannelou : mutations in result in a constitutive activation of type I interferon signalling

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19 déc. 2017
publication

Type I interferon-mediated autoinflammation due to DNase II deficiency

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20 avr. 2017
publication

TBK1/IKKE blockade inhibits mutant STING mediated inflammatory response in patient cells

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18 avr. 2017
publication

Detection of interferon alpha protein reveals differential levels and cellular sources in disease

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10 sept. 2015
project

Biomarker discovery and viral disease pathogenesis

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10 sept. 2015
project

Functional immune response to Mycobacteria tuberculosis derived antigen

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01 déc. 2013
publication

Structural and functional characterization of an orphan ATP-binding cassette ATPase involved in manganese utilization and tolerance in Leptospira spp.

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27 juil. 2007
publication

The crystal structure of M. leprae ML2640c defines a large family of putative S-adenosylmethionine-dependent methyltransferases in mycobacteria

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