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© Research
Publication : The Journal of allergy and clinical immunology

PSMB10, the last immunoproteasome gene missing for PRAAS

Team: Translational Immunology
Member: Darragh Duffy
Member: Vincent Bondet
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in The Journal of allergy and clinical immunology - 26 Nov 2019

Sarrabay G, Méchin D, Salhi A, Boursier G, Rittore C, Crow Y, Rice G, Tran TA, Cezar R, Duffy D, Bondet V, Boudhane L, Broca C, Kant BP, VanGijn M, Grandemange S, Richard E, Apparailly F, Touitou I

Link to Pubmed [PMID] – 31783057

J. Allergy Clin. Immunol. 2020 Mar;145(3):1015-1017

We describe a patient exhibiting clinical features of PRAAS due to a homozygous mutation in PSMB10. This gene encodes the only immunoproteasome subunit in which mutations have not yet been associated with PRAAS.