Our laboratory is based at Institut Pasteur de la Guyane, in French Guiana (a region of France located in South America). We are studying how the mosquito microbiota affects its host and impacts disease transmission.
We notably focus on Anopheles darlingi, the main malaria vector in the Americas, which is still poorly characterised despite its medical importance.
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Publications
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2018The tripartite interactions between the mosquito, its microbiota and Plasmodium, Parasit Vectors 2018 Mar;11(1):200.
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2018Identification and Antibioresistance Characterisation of Culturable Bacteria in the Intestinal Microbiota of Mosquitoes, Vector Biol. J. 2018 Jan;2(2).
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2017A Swiss Army Knife to Cut Malaria Transmission, Cell Host Microbe 2017 Nov;22(5):577-579.
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2017The Peptidoglycan Recognition Proteins PGRPLA and PGRPLB Regulate Anopheles Immunity to Bacteria and Affect Infection by Plasmodium, J Innate Immun 2017 May;.
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2017Microbiota-induced peritrophic matrix regulates midgut homeostasis and prevents systemic infection of malaria vector mosquitoes, PLoS Pathog. 2017 May;13(5):e1006391.
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2017The Mosquito Immune System and Its Interactions With the Microbiota: Implications for Disease Transmission, Arthropod vector (Ed. Stephen K. Wikel, Serap Aksoy & George Dimopoulos) 2017 May 1:101-122.
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2016Larval diet affects mosquito development and permissiveness to Plasmodium infection, Sci Rep 2016 Dec;6:38230.
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2016Seasonality and Locality Affect the Diversity of Anopheles gambiae and Anopheles coluzzii Midgut Microbiota from Ghana, PLoS ONE 2016;11(6):e0157529.
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2016Differential Effects of Azithromycin, Doxycycline, and Cotrimoxazole in Ingested Blood on the Vectorial Capacity of Malaria Mosquitoes, Open Forum Infect Dis 2016 Apr;3(2):ofw074.
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2015Antibiotics in ingested human blood affect the mosquito microbiota and capacity to transmit malaria, Nat Commun 2015 Jan;6:5921.
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Institut Pasteur de Cayenne