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  • member
  • team
  • department
  • center
  • program_project
  • nrc
  • whocc
  • project
  • software
  • tool
  • patent
  • Administrative Staff
  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Clinician Researcher
  • Department Manager
  • Full Professor
  • Graduate Student
  • Honorary Professor
  • Lab assistant
  • Non-permanent Researcher
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Operations
  • Head of Structure
  • Honorary President of the Departement
  • Labex Coordinator
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Scientific Fields
Diseases
Organisms
Applications
Technique
Starting Date
01
Jan 2021
Ending Date
31
Dec 2024
Status
Ongoing
Members
5
Structures
6
Instituts
1

About

Aedes aegypti is the main mosquito vector of several arboviruses of medical significance. Its vectorial capacity is influenced by manifold genetic and environmental factors, including the microbiota. Disentangling genetic and non-genetic drivers of Ae. aegypti microbiota and vectorial capacity is currently hindered by the lack of genetic tools. In this project, we will establish the first genetic panel for Ae. aegypti by creating inbred lines from a natural population in French Guiana. Building on our expertise in Ae. aegypti genomics and biology, we will use this genetic panel to monitor genomic and microbiome evolution during the inbreeding process, and to investigate the genetic basis of the microbiota and vectorial capacity. Knowledge generated by this project will support the development of novel entomological strategies to combat emerging arboviruses. It will also lay the foundation for a future genetic reference panel of Ae. aegypti as a community resource for quantitative genetics research.

Fundings