Thomas Bourgeron

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Positions

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Assistant Professor
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Department Manager
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Appointments

Deputy Director of Center
Deputy Director of Department
Deputy Director of National Reference Center
Deputy Head of Facility
Director of Center
Director of Department
Director of Institute
Director of National Reference Center
Group Leader
Head of Facility
Head of Operations
Head of Structure
Honorary President of the Departement
Labex Coordinator

Content 2

Content Type

member
team
department
center
program_project
nrc
whocc
project
software
tool
patent

Keywords

Positions

Administrative Staff
Assistant Professor
Associate Professor
Clinical Research Assistant
Clinical Research Nurse
Clinician Researcher
Department Manager
Dual-education Student
Full Professor
Honorary Professor
Lab assistant
Master Student
MD-PhD Student
Medical Staff
Non-permanent Researcher
Nursing Staff
Permanent Researcher
Pharmacist
PhD Student
Physician
Post-doc
Prize
Project Manager
Research Associate
Research Engineer
Retired scientist
Technician
Undergraduate Student
Veterinary
Visiting Scientist

Appointments

Deputy Director of Center
Deputy Director of Department
Deputy Director of National Reference Center
Deputy Head of Facility
Director of Center
Director of Department
Director of Institute
Director of National Reference Center
Group Leader
Head of Facility
Head of Operations
Head of Structure
Honorary President of the Departement
Labex Coordinator

Project

Phelan-McDermid Syndrome: from mechanisms to treatments

2020

Publication

Autism-associated SHANK3 mutations impair maturation of neuromuscular junctions and striated muscles.

Science translational medicine

Lutz AK, Pfaender S, Incearap B, Ioannidis V, Ottonelli I, Föhr KJ, Cammerer J, Zoller M, Higelin J, Giona F, Stetter M, Stoecker N, Alami NO, Schön M, Orth M, Liebau S, Barbi G, Grabrucker AM, Delorme R, Fauler M, Mayer B, Jesse S, Roselli F, Ludolph AC, Bourgeron T, Verpelli C, Demestre M, Boeckers TM,

2021

Publication

SHANK3 conformation regulates direct actin binding and crosstalk with Rap1 signaling.

Current biology : CB

Salomaa SI, Miihkinen M, Kremneva E, Paatero I, Lilja J, Jacquemet G, Vuorio J, Antenucci L, Kogan K, Hassani Nia F, Hollos P, Isomursu A, Vattulainen I, Coffey ET, Kreienkamp HJ, Lappalainen P, Ivaska J

2019

Publication

Altered spinogenesis in iPSC-derived cortical neurons from patients with autism carrying de novo SHANK3 mutations.

Scientific reports

Gouder L, Vitrac A, Goubran-Botros H, Danckaert A, Tinevez JY, André-Leroux G, Atanasova E, Lemière N, Biton A, Leblond CS, Poulet A, Boland A, Deleuze JF, Benchoua A, Delorme R, Bourgeron T, Cloëz-Tayarani I,

2023

Publication

Excessive self-grooming, gene dysregulation and imbalance between the striosome and matrix compartments in the striatum of Shank3 mutant mice.

Frontiers in molecular neuroscience

Ferhat AT, Verpy E, Biton A, Forget B, De Chaumont F, Mueller F, Le Sourd AM, Coqueran S, Schmitt J, Rochefort C, Rondi-Reig L, Leboucher A, Boland A, Fin B, Deleuze JF, Boeckers TM, Ey E, Bourgeron T,

2006

Publication

Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders

Nature genetics

Durand CM, Betancur C, Boeckers TM, Bockmann J, Chaste P, Fauchereau F, Nygren G, Rastam M, Gillberg IC, Anckarsäter H, Sponheim E, Goubran-Botros H, Delorme R, Chabane N, Mouren-Simeoni MC, de Mas P, Bieth E, Rogé B, Héron D, Burglen L, Gillberg C, Leboyer M, Bourgeron T

2020

Publication

A chimeric mouse model to study human iPSC-derived neurons: the case of a truncating SHANK3 mutation.

Scientific reports

Vitrac A, Pons S, Balkota M, Lemière N, Raïs C, Bourgeois JP, Maskos U, Bourgeron T, Cloëz-Tayarani I,

Project

Mouse models of ASD

Thomas Bourgeron

Job

Postdoc position: Neurobiology of Autism

Post-doc position: ANR project aiming at investigating the impact of previously known modifiers (stress, lithium, and zinc) on multiple behavioral phenotypes identified in a mouse model of SHANK3 deficiency (Shank3 full Knock-Out) and deciphering […]

Permanent Researcher

Thomas Bourgeron

Human Genetics and Cognitive Functions

Having begun my research career investigating mitochondria in plants and then neurological diseases, I discovered the first mutations of the NLGN3, NLGN4X and SHANK3 genes in autism highlighting the main role of the synapse […]

Job

Functional analysis of social communication and stereotyped behaviours in mouse models of autism

A post-doctoral fellowship position is available for the study of the brain regions involved in social communication and stereotyped behaviours in wild-type mice and in genetic mouse models of autism. We are more specifically […]

Laboratory