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team
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whocc
project
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Deputy Director of Center
Deputy Director of Department
Deputy Director of National Reference Center
Deputy Head of Facility
Director of Center
Director of Department
Director of Institute
Director of National Reference Center
Group Leader
Head of Facility
Head of Operations
Head of Structure
Honorary President of the Departement
Labex Coordinator

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Spontaneous pathology in PS19 tauopathy mice progresses via brain networks.

Neurobiology of disease

Ramirez DMO, Whitesell JD, Bhagwat N, Thomas TL, Ajay AD, Nawaby A, Delatour B, Bay S, LaFaye P, Harris JA, Meeks JP, Diamond MI

Enzymatic Synthesis of Vancomycin-Modified DNA

Molecules

Chiara Figazzolo, Frédéric Bonhomme, Saidbakhrom Saidjalolov, Mélanie Ethève-Quelquejeu, and Marcel Hollenstein*

New Chemical Probe Targeting Bacterial NAD Kinase.

Molecules (Basel, Switzerland)

Clément DA, Leseigneur C, Gelin M, Coelho D, Huteau V, Lionne C, Labesse G, Dussurget O, Pochet S,

Interferon gamma response to Mycobacterium avium subsp. paratuberculosis specific lipopentapeptide antigen L5P in cattle.

Research in veterinary science

Holbert S, Branger M, Souriau A, Lamoureux B, Ganneau C, Richard G, Cochard T, Tholoniat C, Bay S, Winter N, Moyen JL, Biet F,

Benzoyl and pivaloyl as efficient protecting groups for controlled enzymatic synthesis of DNA and XNA oligonucleotides

Asian journal of organic chemistry

Flamme, M.; Katkevica, D.; Pajuste, K.; Katkevics, M.; Sabat, N.; Hanlon, S.; Marzuoli, I.; Püntener, K.; Sladojevich, F.; Hollenstein, M.

Identification of novel leishmanicidal molecules by virtual and biochemical screenings targeting Leishmania eukaryotic translation initiation factor 4A

PLoS neglected tropical diseases

Harigua-Souiai E, Abdelkrim YZ, Bassoumi-Jamoussi I, Zakraoui O, Bouvier G, Essafi-Benkhadir K, Banroques J, Desdouits N, Munier-Lehmann H, Barhoumi M, Tanner NK, Nilges M, Blondel A, Guizani I

Cell wall peptidolipids of Mycobacterium avium: from genetic prediction to exact structure of a nonribosomal peptide.

Molecular microbiology

Bannantine JP, Etienne G, Laval F, Stabel JR, Lemassu A, Daffé M, Bayles DO, Ganneau C, Bonhomme F, Branger M, Cochard T, Bay S, Biet F,

Towards the controlled enzymatic synthesis of LNA containing oligonucleotides.

Frontiers in chemistry

Sabat N, Katkevica D, Pajuste K, Flamme M, Stämpfli A, Katkevics M, Hanlon S, Bisagni S, Püntener K, Sladojevich F, Hollenstein M*

Structure-based design, synthesis and biological evaluation of a NAD+ analogue targeting Pseudomonas aeruginosa NAD kinase.

The FEBS journal

Rahimova R, Nogaret P, Huteau V, Gelin M, Clément DA, Labesse G, Pochet S, Blanc-Potard AB, Lionne C,

A Novel Polyaminocarboxylate Compound To Treat Murine Pulmonary Aspergillosis by Interfering with Zinc Metabolism

Antimicrobial agents and chemotherapy

Laskaris P, Vicentefranqueira R, Helynck O, Jouvion G, Calera JA, du Merle L, Suzenet F, Buron F, de Sousa RA, Mansuy D, Cavaillon JM, Latgé JP, Munier-Lehmann H, Ibrahim-Granet O

Cleaved CD31 as a target for in vivo molecular imaging of inflammation.

Scientific reports

Vigne J, Bay S, Aid-Launais R, Pariscoat G, Rucher G, Sénémaud J, Truffier A, Anizan N, Even G, Ganneau C, Andreata F, Le Borgne M, Nicoletti A, Le Guludec D, Caligiuri G, Rouzet F,

Screening and evaluation of antiviral compounds against Equid alpha-herpesviruses using an impedance-based cellular assay

Virology

Thieulent CJ, Hue ES, Fortier CI, Dallemagne P, Zientara S, Munier-Lehmann H, Hans A, Fortier GD, Pitel PH, Vidalain PO, Pronost SL

Seroreactivity against Specific L5P Antigen from Mycobacterium avium subsp. paratuberculosis in Children at Risk for T1D.

PloS one

Niegowska M, Rapini N, Biet F, Piccinini S, Bay S, Lidano R, Manca Bitti ML, Sechi LA,

C-H Imidation of 7-Deazapurines.

ACS omega

Sabat, N.; Poštová Slavětínská, L.; Klepetářová, B.; Hocek, M.

Design and Synthesis of Naturally-Inspired SARS-CoV-2 Inhibitors

Royal Society Of Chemistry

Hassan H, Chiaravalli J, Hassan A, Bedda I, Krischuns T, Chen K-Y, Shi Ming LI A, Delpal A, Decroly E, Vedadi M, Naffakh N, Agou F, Mallart S, Arafa R K, Aromondo PB

Design, synthesis, biophysical and biological evaluation of original condensed pyrrolopyrimidine and pyrrolopyridine ligands as anti-SARS-CoV-2 agents targeting G4

European Journal of Medicinal Chemistry

Jean Guillon, Solène Savrimoutou, Nicolas da Rocha, Sandra Albenque-Rubio, Olivier Helynck, Cyrielle Durand, Jeanne Chiaravalli, Noël Pinaud, Luisa Ronga, Stéphane Moreau, Simon Chirold, Tshering Zangmo, Melika Arab, Lindita Lari, Jean‐louis Mergny, Hélène Munier-Lehmann, Marc Lavigne

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Expanding species diversity in the monotypic genera Thalassoporum and Tumidithrix (Pseudanabaenales, Cyanobacteriota) with the description of Thalassoporum mexicanum sp. nov. and Tumidithrix helvetica sp. nov.

Weekly Screening of Circulating Mucorales DNA and early treatment in Severely Burned Patients Improves Survival: Real-Life Bi-center Experience in France.

Calls

Creation of new junior research groups at the Institut Pasteur – Call for applications 2026

2026 René and Andrée Duquesne Prize

2026 Pasteur Vallery-Radot Prize

Events

11 Upcoming Events

Calendar

Today

09 Feb 2026

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Demonstration of the BD FACSDiscover A8™

Antibody Engineering

Chemistry of Biomolecules

UMR3523 – Chemistry for Life Sciences (Chem4Life)

UMR3528 – Structural Molecular Biology and Infectious Process

Immunology Dpt. Seminar , Prof. Ivaylo Ivanov, from Columbia University Irving Medical Center, NY, USA. ” Microbiota Control of Host Immunity “ – Ivaylo Ivanov, Ph.D.

Antibody Engineering

Chemistry of Biomolecules

UMR3523 – Chemistry for Life Sciences (Chem4Life)

UMR3528 – Structural Molecular Biology and Infectious Process

Tumor Hypoxia – the Hidden Driver of Cancer Recurrence and Genome Instability – Hiroshi HARADA, Ph.D.

Antibody Engineering

Chemistry of Biomolecules

UMR3523 – Chemistry for Life Sciences (Chem4Life)

UMR3528 – Structural Molecular Biology and Infectious Process

Department of Parasites and Insect Vectors Seminar : Franziska Hentzschel “Nuclear actin regulates genome segregation during Plasmodium mitosis in the mosquito”

Antibody Engineering

Chemistry of Biomolecules

UMR3523 – Chemistry for Life Sciences (Chem4Life)

UMR3528 – Structural Molecular Biology and Infectious Process

EPI-PROTEOMICS TO DECODE CHROMATIN AND PROTEIN METHYLATION REWIRING IN CANCER THERAPY RESISTANCE

Antibody Engineering

Chemistry of Biomolecules

UMR3523 – Chemistry for Life Sciences (Chem4Life)

UMR3528 – Structural Molecular Biology and Infectious Process

Women’s Health, Women in Health

Antibody Engineering

Chemistry of Biomolecules

UMR3523 – Chemistry for Life Sciences (Chem4Life)

UMR3528 – Structural Molecular Biology and Infectious Process

Jobs

Job: Permanent Researcher

G5 call — Institut Pasteur

Job: Research Engineer

Research engineer position in single-cell multi-omics integration

Machine Learning for integrative genomics

Post-doctoral position – Subtil Lab

Cellular Biology of Microbial Infection

Postdoc position for a (bio)physicist, engineer or computational scientist

Imaging and Modeling

Network

Publications

Proceedings of the National Academy of Sciences of the United States of America

Evolution of abiotic cubane chemistries in a nucleic acid aptamer allows selective recognition of a malaria biomarker.

Nature communications

Germline inherited small RNAs facilitate the clearance of untranslated maternal mRNAs in C. elegans embryos.

Current opinion in cell biology

Staying away from the breaking point: Probing the limits of epithelial cell elimination.

Current biology : CB

Competition for Space Induces Cell Elimination through Compaction-Driven ERK Downregulation.

News

Demonstration of the BD FACSDiscover A8™

Pasteur Lunch & Learn Easypanel / OMIQ

TOP Paper of the Year in Gut 2025 — Benoît CHASSAING, Héloïse RYTTER and cowor...

Symposium : Spencer Shorte, remembering a visionary mind