I currently lead a research unit in the Virology department of Institut Pasteur. My research interests lie in RNA virus discovery, emergence, transmission, and evolution. Within the group, we use viral genomics to study […]
Intracellular traffic and cell compartmentalization Eukaryotic cells contain extensive internal membranes defining many compartments having each specific functions. However these organelles are constantly moving and reshaping, still retaining their identity. The maintenance of cell […]
Francois Schweisguth studied at the Ecole Normale Superieure in Paris (1983-88) and obtained a PhD in Developmental Biology in 1990 under the supervision of Jean-Antoine Lepesant (IJM, Paris) and Alain Vincent (CBD, Toulouse). He […]
Dr. Gerald Späth currently holds a Research Director position at the Institut Pasteur in Paris, where he directs the Unit ‘Parasitologie moléculaire et Signalisation’ (12 members) and the Department ‘Parasites and Insect Vectors’ (ca. […]
Pascale Pescher is a research engineer in the unit ‘Parasitologie moléculaire et signalisation’. She started her career working on host-mycobacteria interactions and since 2006 joined the field of Leishmania research studying the molecular basis […]
Virus-host ribonucleoprotein complexes and innate immunity The RIG-I-like receptors (RLRs) play a major role in sensing intracytoplasmic RNA virus infection to initiate and modulate antiviral immunity. These RNA helicases interact with particular signatures of […]
I’m a trained biophysicist and develop integrated approaches combining fluorescence imaging, wetlab experiments, computerised image analysis, and mathematical modeling. We apply this methods to study RNA regulation across several scales, ranging from sub-cellular RNA […]