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  • tool
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  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Clinical Research Nurse
  • Clinician Researcher
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  • Dual-education Student
  • Full Professor
  • Honorary Professor
  • Lab assistant
  • Master Student
  • MD-PhD Student
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  • PhD Student
  • Physician
  • Post-doc
  • Prize
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  • Research Engineer
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  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
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About

About me

I am a trained biophysicist specializing in the development of integrated methodologies that combine fluorescence imaging, wet lab experiments, computerized image analysis, and mathematical modeling.

I hold an undergraduate degree in Computational Physics from Graz, Austria. My Ph.D. research at the NIH in Bethesda, USA, focused on studying the in-vivo binding properties of nuclear proteins using live-cell fluorescence microscopy and mathematical modeling. After completing my Ph.D., I continued at the NIH for a brief postdoc, analyzing a biochemical assay to measure locus-specific DNA residence times.

Subsequently, I worked as a postdoc at ENS Paris and Institut Pasteur in Paris (France), where I developed automated image processing tools and mathematical models to gain a quantitative understanding of transcription regulation. In 2013, I joined Pasteur as a staff scientist. Since 2023, I have been leading the Quantitative RNA Imaging groupSince 2025, I have been acting as the interim head of the Photonic BioImaging (PBI) platform.

Current position

I am currently serving as the interim head of the Photonic BioImaging (PBI) platform. PBI specializes in advanced optical microscopy techniques, providing crucial imaging expertise for life sciences research. Our platform is dedicated to service rendering, training, technology-driven research, and development of innovative microscopy approaches

In addition to my role with PBI, I lead the Quantitative RNA Imaging group within the platform. We primarily investigate RNA regulation across various spatial scales, utilizing single RNA imaging to address complex biological questions. Our research is supported by a network of national and international collaborations, aiming to advance our understanding of RNA synthesis, processing, and transcription.

Projects

Software

CV

EDUCATION

HDR

  • Thesis: Exploring spatio-temporal transcriptional regulation

Ph.D.

  • Graz University of Technology, Austria and National Institutes of Health (NIH), Bethesda; 2005 – 2008
  • Thesis: Quantitative analysis of the dynamic properties of chromatin associated proteins by FRAP experiments
  • Advisors: Dr. James G. McNally, Dr. Zlatko Trajanoski

M.S.

  • Computational Physics, Universität Graz, Austria, 1999 – 2005
  • Thesis: Numerical Simulations of FRAP Experiments
  • Advisors: Dr. Max Lippitsch, Dr. Zlatko Trajanoski

Publications

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