Molecular and Structural Biology and Chemistry [516]
Simon Wain-Hobson
Mycology
The Mycology Department at Institut Pasteur studies yeasts and filamentous fungi responsible for fungal infections in humans. Multidisciplinary approaches are used to explore the biology of fungal pathogens and fungal pathogenesis, with the aim […]
Christine Petit
Auditory Therapies Innovation Lab
SCIENTIFIC POSITIONS Head of Auditory Therapies Innovation Laboratory at the Hearing Institute (an Institut Pasteur Center), Paris Professor “Classe Exceptionnelle” at Institut Pasteur, Paris Professor Emeritus at Collège de France, Chair of Genetics […]
Pierre-Jean Corringer
Signaling and receptors dynamics
I was trained as a chemist and did my PhD (Paris) and post-doctoral fellowship (Brighton) in organic synthesis. He then joined the Pasteur Institute as a CNRS researcher to work on nicotinic acetylcholine receptors, […]
Pascale Cossart
Bacteria-Cell Interactions
Pascale Cossart has since 1986 investigated how bacterial pathogens interact with mammalian cells during infection. She has pioneered and documented in details how bacteria by using a multitude of complementary strategies, – including posttranslational […]
Thermodynamic stability of macromolecules
Circular dichroism (CD) spectroscopy allows the determination of secondary and tertiary structures, the analysis of conformational changes and the measure of thermal and chemical stability of folding. Differential Scanning Calorimetry (DSC) gives access to […]
Secondary and tertiary structures of macromolecules
Circular dichroism (CD) allows the measurement of secondary and tertiary structures, the analyse of conformational changes, the kinetic of folding and the thermal and chemical stability of folding. Fluorescence spectroscopy gives access to the […]
Size and Shape of Macromolecules and their assemblies
Analytical Ultracentrifugation gives access to the mass and shape of macromolecules in solution, allowing to evaluate their oligomerization state, their stoichiometry and the equilibrium constant of assemblies. Dynamic Light Scattering (cuvette or microplaque) allows […]
Stoichiometry of Macromolecular Assemblies
Static Light Scattering allows to measure the mass and intrinsic viscosity of macromolecules Analytical Ultracentrifugation gives access to the oligomerization state and the stoichiometry of molecular assemblies