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Deputy Director of National Reference Center
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Director of Center
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Director of Institute
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Christine Petit

Development, developmental genetics, pattern formation and organogenesis [77]

Permanent Researcher

Pierre-Marie Lledo

UMR3571 – Genes, Synapses and Cognition

Much of our adult behaviors reflect the state of neural circuits sculpted by sensory experience in infancy and early childhood. At no other time in life does the surrounding environment so potently shape most […]

Cell biology of Notch

François Schweisguth

Fate patterning and self-organized Notch dynamics

François Schweisguth

Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors

Nature

Gomez Perdiguero E, Klapproth K, Schulz C, Busch K, Azzoni E, Crozet L, Garner H, Trouillet C, de Bruijn MF, Geissmann F, Rodewald HR

Auditory Therapies Innovation Lab

Christine Petit

Parasites and Insect Vectors

The Parasites and Insect Vectors Department investigates the life cycle of parasites and their vectors. This research addresses global public health concerns and tackles the ongoing need for better prevention, control, and treatment. The department […]

Developmental and Stem Cell Biology

Developmental biology first made its appearance at Institut Pasteur when François Jacob, François Gros and their colleagues extended their pioneering work on mRNA in bacteria to gene regulation in eukaryotic systems. This led to […]

Myb-independent macrophages: a family of cells that develops with their tissue of residence and is involved in its homeostasis

Cold Spring Harbor symposia on quantitative biology

Gomez Perdiguero E, Geissmann F

Lymphomyeloid contribution of an immune-restricted progenitor emerging prior to definitive hematopoietic stem cells

Cell stem cell

Böiers C, Carrelha J, Lutteropp M, Luc S, Green JC, Azzoni E, Woll PS, Mead AJ, Hultquist A, Swiers G, Perdiguero EG, Macaulay IC, Melchiori L, Luis TC, Kharazi S, Bouriez-Jones T, Deng Q, Pontén A, Atkinson D, Jensen CT, Sitnicka E, Geissmann F, Godin I, Sandberg R, de Bruijn MF, Jacobsen SE

Fuz mutant mice reveal shared mechanisms between ciliopathies and FGF-related syndromes

Developmental cell

Tabler JM, Barrell WB, Szabo-Rogers HL, Healy C, Yeung Y, Perdiguero EG, Schulz C, Yannakoudakis BZ, Mesbahi A, Wlodarczyk B, Geissmann F, Finnell RH, Wallingford JB, Liu KJ

Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways

Nature neuroscience

Kierdorf K, Erny D, Goldmann T, Sander V, Schulz C, Perdiguero EG, Wieghofer P, Heinrich A, Riemke P, Hölscher C, Müller DN, Luckow B, Brocker T, Debowski K, Fritz G, Opdenakker G, Diefenbach A, Biber K, Heikenwalder M, Geissmann F, Rosenbauer F, Prinz M

Development and homeostasis of “resident” myeloid cells: the case of the microglia

Glia

Gomez Perdiguero E, Schulz C, Geissmann F

A lineage of myeloid cells independent of Myb and hematopoietic stem cells

Science (New York, N.Y.)

Schulz C, Gomez Perdiguero E, Chorro L, Szabo-Rogers H, Cagnard N, Kierdorf K, Prinz M, Wu B, Jacobsen SE, Pollard JW, Frampton J, Liu KJ, Geissmann F