• 2024
  Nicola Festuccia, Sandrine Vandormael-Pournin, Almira Chervova, Anna Geiselman, Francina Langa, Rémi-Xavier Coux, Inma Gonzalez, Guillaume Giraud Collet, Michel Cohen-Tannoudji, Pablo Navarro, Nr5a2 is dispensable for zygotic genome activation but essential for morula development, Science, 2024, 386 (6717), pp.eadg7325. ⟨10.1126/science.adg7325⟩.
• 2023
  Thaller AL, Jönsson F, Fiquet O, Marie S, Doisne JM, Girelli-Zubani G, Eri T, Fernandes P, Tatirovsky E, Langa-Vives F, Bruhns P, Strick-Marchand H, Di Santo JP, A human immune system (HIS) mouse model that dissociates roles for mouse and human FcR+ cells during antibody-mediated immune responses., Eur J Immunol 2023 Aug; (): e2350454.
• 2023
  Le Chevalier F, Authié P, Chardenoux S, Bourgine M, Vesin B, Cussigh D, Sassier Y, Fert I, Noirat A, Nemirov K, Anna F, Bérard M, Guinet F, Hardy D, Charneau P, Lemonnier F, Langa-Vives F, Majlessi L, Mice Humanized for MHC and hACE2 with High Permissiveness to SARS-CoV-2 Omicron Replication., Microbes Infect 2023 Apr; (): 105142.
• 2022
  Russo E, Lemaître F, Corre B, Chikina AS, Langa-Vives F, Bousso P, , SPICE-Met: profiling and imaging energy metabolism at the single-cell level using a fluorescent reporter mouse., EMBO J 2022 Aug; (): e111528.
• 2022
  Vesin B, Lopez J, Noirat A, Authié P, Fert I, Le Chevalier F, Moncoq F, Nemirov K, Blanc C, Planchais C, Mouquet H, Guinet F, Hardy D, Vives FL, Gerke C, Anna F, Bourgine M, Majlessi L, Charneau P, , An intranasal lentiviral booster reinforces the waning mRNA vaccine-induced SARS-CoV-2 immunity that it targets to lung mucosa., Mol Ther 2022 Apr; (): .
• 2022
  Dos Santos M, Backer S, Auradé F, Wong MM, Wurmser M, Pierre R, Langa F, Do Cruzeiro M, Schmitt A, Concordet JP, Sotiropoulos A, Jeffrey Dilworth F, Noordermeer D, Relaix F, Sakakibara I, Maire P, , A fast Myosin super enhancer dictates muscle fiber phenotype through competitive interactions with Myosin genes., Nat Commun 2022 02; 13(1): 1039.
• 2021
  Ku MW, Authié P, Bourgine M, Anna F, Noirat A, Moncoq F, Vesin B, Nevo F, Lopez J, Souque P, Blanc C, Fert I, Chardenoux S, Lafosse L, Cussigh D, Hardy D, Nemirov K, Guinet F, Langa Vives F, Majlessi L, Charneau P, , Brain cross-protection against SARS-CoV-2 variants by a lentiviral vaccine in new transgenic mice., EMBO Mol Med 2021 12; 13(12): e14459.
• 2021
  Foray AP, Candon S, Hildebrand S, Marquet C, Valette F, Pecquet C, Lemoine S, Langa-Vives F, Dumas M, Hu P, Santamaria P, You S, Lyon S, Scott L, Bu CH, Wang T, Xu D, Moresco EMY, Scazzocchio C, Bach JF, Beutler B, Chatenoud L, , De novo germline mutation in the dual specificity phosphatase 10 gene accelerates autoimmune diabetes., Proc Natl Acad Sci U S A 2021 11; 118(47): .
• 2021
  Dubois-Vedrenne I, Al Delbany D, De Henau O, Robert V, Vernimmen M, Langa F, Lefort A, Libert F, Wittamer V, Parmentier M, , The antitumoral effects of chemerin are independent from leukocyte recruitment and mediated by inhibition of neoangiogenesis., Oncotarget 2021 Sep; 12(19): 1903-1919.
• 2021
  Maurizy C, Abeza C, Lemmers B, Gabola M, Longobardi C, Pinet V, Ferrand M, Paul C, Bremond J, Langa F, Gerbe F, Jay P, Verheggen C, Tinari N, Helmlinger D, Lattanzio R, Bertrand E, Hahne M, Pradet-Balade B, , The HSP90/R2TP assembly chaperone promotes cell proliferation in the intestinal epithelium., Nat Commun 2021 08; 12(1): 4810.
• 2021
  Benavente-Diaz M, Comai G, Di Girolamo D, Langa F, Tajbakhsh S, , Dynamics of myogenic differentiation using a novel Myogenin knock-in reporter mouse., Skelet Muscle 2021 Feb; 11(1): 5.
• 2021
  Houzelstein D, Simon-Chazottes D, Batista L, Tokuda S, Langa Vives F, Flamand M, Montagutelli X, Panthier JJ, , The ring finger protein 213 gene (Rnf213) contributes to Rift Valley fever resistance in mice., Mamm Genome 2021 02; 32(1): 30-37.
• 2021
  Hörnblad A, Bastide S, Langenfeld K, Langa F, Spitz F, , Dissection of the Fgf8 regulatory landscape by in vivo CRISPR-editing reveals extensive intra- and inter-enhancer redundancy., Nat Commun 2021 01; 12(1): 439.
• 2021
  Gamblin C, Rouault C, Lacombe A, Langa-Vives F, Farabos D, Lamaziere A, Clément K, Gautier EL, Yvan-Charvet L, Dugail I, , Lysosomal Acid Lipase Drives Adipocyte Cholesterol Homeostasis and Modulates Lipid Storage in Obesity, Independent of Autophagy., Diabetes 2021 01; 70(1): 76-90.
• 2020
  Delavallée L, Mathiah N, Cabon L, Mazeraud A, Brunelle-Navas MN, Lerner LK, Tannoury M, Prola A, Moreno-Loshuertos R, Baritaud M, Vela L, Garbin K, Garnier D, Lemaire C, Langa-Vives F, Cohen-Salmon M, Fernández-Silva P, Chrétien F, Migeotte I, Susin SA, , Mitochondrial AIF loss causes metabolic reprogramming, caspase-independent cell death blockade, embryonic lethality, and perinatal hydrocephalus., Mol Metab 2020 10; 40(): 101027.
• 2020
  Sawade L, Grandi F, Mignanelli M, Patiño-López G, Klinkert K, Langa-Vives F, Di Guardo R, Echard A, Bolino A, Haucke V, , Rab35-regulated lipid turnover by myotubularins represses mTORC1 activity and controls myelin growth., Nat Commun 2020 06; 11(1): 2835.
• 2019
  Dubois-Vedrenne I, De Henau O, Robert V, Langa F, Al Delbany D, Vosters O, Angelats-Canals E, Vernimmen M, Luangsay S, Wittamer V, Parmentier M, Expression of Bioactive Chemerin by Keratinocytes Inhibits Late Stages of Tumor Development in a Chemical Model of Skin Carcinogenesis, Front Oncol 2019;9:1253.
• 2019
  Benyelles M, Episkopou H, O'Donohue MF, Kermasson L, Frange P, Poulain F, Burcu Belen F, Polat M, Bole-Feysot C, Langa-Vives F, Gleizes PE, de Villartay JP, Callebaut I, Decottignies A, Revy P, Impaired telomere integrity and rRNA biogenesis in PARN-deficient patients and knock-out models, EMBO Mol Med 2019 07;11(7):e10201.
• 2019
  Glenda Comai, Eglantine Heude, Sebastian Mella, Sylvain Paisant, Francesca Pala, Mirialys Gallardo, Francina Langa, Gabrielle Kardon, Swetha Gopalakrishnan, Shahragim Tajbakhsh, A distinct cardiopharyngeal mesoderm genetic hierarchy establishes antero-posterior patterning of esophagus striated muscle, eLife, 2019, 8, pp.e47460. ⟨10.7554/eLife.47460⟩.
• 2018
  Forget B, Scholze P, Langa F, Morel C, Pons S, Mondoloni S, Besson M, Durand-de Cuttoli R, Hay A, Tricoire L, Lambolez B, Mourot A, Faure P, Maskos U, , A Human Polymorphism in CHRNA5 Is Linked to Relapse to Nicotine Seeking in Transgenic Rats., Curr Biol 2018 Oct; 28(20): 3244-3253.e7.
• 2017
  Lesport E, Ferster A, Biver A, Roch B, Vasquez N, Jabado N, Vives FL, Revy P, Soulier J, de Villartay JP, Reduced recruitment of 53BP1 during interstrand crosslink repair is associated with genetically inherited attenuation of mitomycin C sensitivity in a family with Fanconi anemia, Oncotarget 2018 Jan;9(3):3779-3793.
• 2017
  Phelep A, Laouari D, Bharti K, Burtin M, Tammaccaro S, Garbay S, Nguyen C, Vasseur F, Blanc T, Berissi S, Langa-Vives F, Fischer E, Druilhe A, Arnheiter H, Friedlander G, Pontoglio M, Terzi F, MITF – A controls branching morphogenesis and nephron endowment, PLoS Genet. 2017 12;13(12):e1007093.
• 2016
  Forand A, Koumakis E, Rousseau A, Sassier Y, Journe C, Merlin JF, Leroy C, Boitez V, Codogno P, Friedlander G, Cohen I, , Disruption of the Phosphate Transporter Pit1 in Hepatocytes Improves Glucose Metabolism and Insulin Signaling by Modulating the USP7/IRS1 Interaction., Cell Rep 2016 11; 17(7): 1905.
• 2016
  Lebailly B, Langa F, Boitard C, Avner P, Rogner UC, The circadian gene Arntl2 on distal mouse chromosome 6 controls thymocyte apoptosis, Mamm. Genome 2017 02;28(1-2):1-12.
• 2016
  Forand A, Koumakis E, Rousseau A, Sassier Y, Journe C, Merlin JF, Leroy C, Boitez V, Codogno P, Friedlander G, Cohen I, , Disruption of the Phosphate Transporter Pit1 in Hepatocytes Improves Glucose Metabolism and Insulin Signaling by Modulating the USP7/IRS1 Interaction., Cell Rep 2016 09; 16(10): 2736-2748.
• 2016
  Cubillos-Rojas M, Schneider T, Hadjebi O, Pedrazza L, de Oliveira JR, Langa F, Guénet JL, Duran J, de Anta JM, Alcántara S, Ruiz R, Pérez-Villegas EM, Aguilar-Montilla FJ, Carrión ÁM, Armengol JA, Baple E, Crosby AH, Bartrons R, Ventura F, Rosa JL, The HERC2 ubiquitin ligase is essential for embryonic development and regulates motor coordination, Oncotarget 2016 Aug;7(35):56083-56106.
• 2016
  Lemoine A, Chauveau-Le Friec G, Langa F, Louvet C, Generation of a Double KO Mouse by Simultaneous Targeting of the Neighboring Genes Tmem176a and Tmem176b Using CRISPR/Cas9: Key Steps from Design to Genotyping, J Genet Genomics 2016 05;43(5):329-40.
• 2016
  Abby E, Tourpin S, Ribeiro J, Daniel K, Messiaen S, Moison D, Guerquin J, Gaillard JC, Armengaud J, Langa F, Toth A, Martini E, Livera G, Implementation of meiosis prophase I programme requires a conserved retinoid-independent stabilizer of meiotic transcripts, Nat Commun 2016 Jan;7:10324.
• 2015
  Daubas P, Duval N, Bajard L, Langa Vives F, Robert B, Mankoo BS, Buckingham M, Fine-tuning the onset of myogenesis by homeobox proteins that interact with the Myf5 limb enhancer, Biol Open 2015 Nov;4(12):1614-24.
• 2014
  Serra-Hassoun M, Bourgine M, Boniotto M, Berges J, Langa F, Michel ML, Freitas AA, Garcia S, Human hematopoietic reconstitution and HLA-restricted responses in nonpermissive alymphoid mice, J. Immunol. 2014 Aug;193(3):1504-11.
• 2014
  Papanayotou C, Benhaddou A, Camus A, Perea-Gomez A, Jouneau A, Mezger V, Langa F, Ott S, Sabéran-Djoneidi D, Collignon J, A novel nodal enhancer dependent on pluripotency factors and smad2/3 signaling conditions a regulatory switch during epiblast maturation, PLoS Biol. 2014 Jun;12(6):e1001890.
• 2014
  Révy D, Jaouen F, Salin P, Melon C, Chabbert D, Tafi E, Concetta L, Langa F, Amalric M, Kerkerian-Le Goff L, Marie H, Beurrier C, Cellular and behavioral outcomes of dorsal striatonigral neuron ablation: new insights into striatal functions, Neuropsychopharmacology 2014 Oct;39(11):2662-72.
• 2014
  Samandary S, Kridane-Miledi H, Sandoval JS, Choudhury Z, Langa-Vives F, Spencer D, Chentoufi AA, Lemonnier FA, BenMohamed L, Associations of HLA-A, HLA-B and HLA-C alleles frequency with prevalence of herpes simplex virus infections and diseases across global populations: implication for the development of an universal CD8+ T-cell epitope-based vaccine, Hum. Immunol. 2014 Aug;75(8):715-29.
• 2014
  Si-Tahar M, Blanc F, Furio L, Chopy D, Balloy V, Lafon M, Chignard M, Fiette L, Langa F, Charneau P, Pothlichet J, Protective role of LGP2 in influenza virus pathogenesis, J. Infect. Dis. 2014 Jul;210(2):214-23.
• 2013
  Boucherma R, Kridane-Miledi H, Bouziat R, Rasmussen M, Gatard T, Langa-Vives F, Lemercier B, Lim A, Bérard M, Benmohamed L, Buus S, Rooke R, Lemonnier FA, HLA-A*01:03, HLA-A*24:02, HLA-B*08:01, HLA-B*27:05, HLA-B*35:01, HLA-B*44:02, and HLA-C*07:01 monochain transgenic/H-2 class I null mice: novel versatile preclinical models of human T cell responses, J. Immunol. 2013 Jul;191(2):583-93.
• 2013
  Zarantonelli ML, Skoczynska A, Antignac A, El Ghachi M, Deghmane AE, Szatanik M, Mulet C, Werts C, Peduto L, d'Andon MF, Thouron F, Nato F, Lebourhis L, Philpott DJ, Girardin SE, Vives FL, Sansonetti P, Eberl G, Pedron T, Taha MK, Boneca IG, , Penicillin resistance compromises Nod1-dependent proinflammatory activity and virulence fitness of neisseria meningitidis., Cell Host Microbe 2013 Jun; 13(6): 735-45.
• 2012
  Lallemand Y, Moreau J, Cloment CS, Vives FL, Robert B, Generation and characterization of a tamoxifen inducible Msx1(CreERT2) knock-in allele, Genesis 2013 Feb;51(2):110-9.
• 2012
  Dulauroy S, Di Carlo SE, Langa F, Eberl G, Peduto L, Lineage tracing and genetic ablation of ADAM12(+) perivascular cells identify a major source of profibrotic cells during acute tissue injury, Nat. Med. 2012 Aug;18(8):1262-70.
• 2012
  Nouët Y, Dahan J, Labalette C, Levillayer F, Julien B, Jouvion G, Cairo S, Vives FL, Ribeiro A, Huerre M, Colnot S, Perret C, Nhieu JT, Tordjmann T, Buendia MA, Wei Y, The four and a half LIM-only protein 2 regulates liver homeostasis and contributes to carcinogenesis, J. Hepatol. 2012 Nov;57(5):1029-36.
• 2012
  Fenina M, Simon-Chazottes D, Vandormael-Pournin S, Soueid J, Langa F, Cohen-Tannoudji M, Bernard BA, Panthier JJ, I-SceI-mediated double-strand break does not increase the frequency of homologous recombination at the Dct locus in mouse embryonic stem cells, PLoS ONE 2012;7(6):e39895.
• 2012
  Boucherma R, Kridane-Miledi H, Vives FL, Vauchy C, Borg C, Kleinclauss F, Fiette L, Tiberghien P, Lemonnier FA, Rohrlich PS, Huetz F, Loss of central and peripheral CD8+ T-cell tolerance to HFE in mouse models of human familial hemochromatosis, Eur. J. Immunol. 2012 Apr;42(4):851-62.
• 2011
  Grey C, Barthès P, Chauveau-Le Friec G, Langa F, Baudat F, de Massy B, Mouse PRDM9 DNA-binding specificity determines sites of histone H3 lysine 4 trimethylation for initiation of meiotic recombination, PLoS Biol. 2011 Oct;9(10):e1001176.
• 2010
  Sawa S, Cherrier M, Lochner M, Satoh-Takayama N, Fehling HJ, Langa F, Di Santo JP, Eberl G, Lineage relationship analysis of RORgammat+ innate lymphoid cells, Science 2010 Oct;330(6004):665-9.
• 2009
  Mashimo T, Hadjebi O, Amair-Pinedo F, Tsurumi T, Langa F, Serikawa T, Sotelo C, Guénet JL, Rosa JL, Progressive Purkinje cell degeneration in tambaleante mutant mice is a consequence of a missense mutation in HERC1 E3 ubiquitin ligase, PLoS Genet. 2009 Dec;5(12):e1000784.
• 2009
  Alves NL, Richard-Le Goff O, Huntington ND, Sousa AP, Ribeiro VS, Bordack A, Vives FL, Peduto L, Chidgey A, Cumano A, Boyd R, Eberl G, Di Santo JP, Characterization of the thymic IL-7 niche in vivo, Proc. Natl. Acad. Sci. U.S.A. 2009 Feb;106(5):1512-7.
• 2008
  Disson O, Grayo S, Huillet E, Nikitas G, Langa-Vives F, Dussurget O, Ragon M, Le Monnier A, Babinet C, Cossart P, Lecuit M, , Conjugated action of two species-specific invasion proteins for fetoplacental listeriosis., Nature 2008 Oct; 455(7216): 1114-8.
• 2008
  Lochner M, Peduto L, Cherrier M, Sawa S, Langa F, Varona R, Riethmacher D, Si-Tahar M, Di Santo JP, Eberl G, In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORgamma t+ T cells, J. Exp. Med. 2008 Jun;205(6):1381-93.
• 2008
  Bensoussan V, Lallemand Y, Moreau J, Cloment CS, Langa F, Robert B, Generation of an Msx2-GFP conditional null allele, Genesis 2008 May;46(5):276-82.
• 2007
  Zarantonelli ML, Szatanik M, Giorgini D, Hong E, Huerre M, Guillou F, Alonso JM, Taha MK, , Transgenic mice expressing human transferrin as a model for meningococcal infection., Infect Immun 2007 Dec; 75(12): 5609-14.
• 2007
  Hyenne V, Souilhol C, Cohen-Tannoudji M, Cereghini S, Petit C, Langa F, Maro B, Simmler MC, Conditional knock-out reveals that zygotic vezatin-null mouse embryos die at implantation, Mech. Dev. 2007 Jul;124(6):449-62.
• 2007
  Monet M, Domenga V, Lemaire B, Souilhol C, Langa F, Babinet C, Gridley T, Tournier-Lasserve E, Cohen-Tannoudji M, Joutel A, The archetypal R90C CADASIL-NOTCH3 mutation retains NOTCH3 function in vivo, Hum. Mol. Genet. 2007 Apr;16(8):982-92.
• 2006
  Delmaghani S, del Castillo FJ, Michel V, Leibovici M, Aghaie A, Ron U, Van Laer L, Ben-Tal N, Van Camp G, Weil D, Langa F, Lathrop M, Avan P, Petit C, Mutations in the gene encoding pejvakin, a newly identified protein of the afferent auditory pathway, cause DFNB59 auditory neuropathy, Nat. Genet. 2006 Jul;38(7):770-8.