• 2023
  Collados Rodríguez M, Maillard P, Journeaux A, Komarova AV, Najburg V, David RS, Helynck O, Guo M, Zhong J, Baize S, Tangy F, Jacob Y, Munier-Lehmann H, Meurs EF, Novel Antiviral Molecules against Ebola Virus Infection., Int J Mol Sci 2023 Sep; 24(19): .
• 2022
  Nicolas Vabret, Valérie Najburg, Alexander Solovyov, Ramya Gopal, Christopher Mcclain, Petr Šulc, Sreekumar Balan, Yannis Rahou, Guillaume Beauclair, Maxime Chazal, Hugo Varet, Rachel Legendre, Odile Sismeiro, Raul Y. Sanchez David, Lise Chauveau, Nolwenn Jouvenet, Martin Markowitz, Sylvie van der Werf, Olivier Schwartz, Frédéric Tangy, Nina Bhardwaj, Benjamin D. Greenbaum, Anastassia V. Komarova, Y RNAs are conserved endogenous RIG-I ligands across RNA virus infection and are targeted by HIV-1, iScience, 2022, 25 (7), pp.104599. ⟨10.1016/j.isci.2022.104599⟩.
• 2021
  Andrea Di Gioacchino, Rachel Legendre, Yannis Rahou, Valérie Najburg, Pierre Charneau, Benjamin Greenbaum, Frédéric Tangy, Sylvie van Der Werf, Simona Cocco, Anastassia Komarova, sgDI-tector: defective interfering viral genome bioinformatics for detection of coronavirus subgenomic RNAs, RNA, 2021, 28 (3), pp.277-289. ⟨10.1261/rna.078969.121⟩.
• 2021
  Phanramphoei N. Frantz, Aleksandr Barinov, Claude Ruffié, Chantal Combredet, Valérie Najburg, Guilherme Dias de Melo, Florence Larrous, Lauriane Kergoat, Samaporn Teeravechyan, Anan Jongkaewwattana, Emmanuelle Billon-Denis, Jean-Nicolas Tournier, Matthieu Prot, Laurine Levillayer, Laurine Conquet, Xavier Montagutelli, Magali Tichit, David Hardy, Priyanka Fernandes, Hélène Strick-Marchand, James Di Santo, Etienne Simon-Lorière, Hervé Bourhy, Frédéric Tangy, A live measles-vectored COVID-19 vaccine induces strong immunity and protection from SARS-CoV-2 challenge in mice and hamsters, Nature Communications, 2021, 12 (1), pp.6277. ⟨10.1038/s41467-021-26506-2⟩.
• 2021
  Sarah Lesage, Maxime Chazal, Guillaume Beauclair, Damien Batalie, Silvia Cerboni, Elodie Couderc, Aurianne Lescure, Elaine del Nery, Frédéric Tangy, Annette Martin, Nicolas Manel, Nolwenn Jouvenet, Discovery of genes that modulate flavivirus replication in an interferon-dependent manner, Journal of Molecular Biology, 2021, pp.167277. ⟨10.1016/j.jmb.2021.167277⟩.
• 2021
  Mateo M, Reynard S, Journeaux A, Germain C, Hortion J, Carnec X, Picard C, Baillet N, Borges-Cardoso V, Merabet O, Vallve A, Barron S, Jourjon O, Lacroix O, Duthey A, Dirheimer M, Jouvion G, Moreau PH, Fellmann L, Carbonnelle C, Raoul H, Tangy F, Baize S, , A single-shot Lassa vaccine induces long-term immunity and protects cynomolgus monkeys against heterologous strains., Sci Transl Med 2021 Jun; 13(597): .
• 2021
  Alice Meignié, Chantal Combredet, Marc Santolini, István Kovács, Thibaut Douché, Quentin Giai Gianetto, Hyeju Eun, Mariette I Matondo, Yves Jacob, Regis Grailhe, Frédéric Tangy, Anastassia V. Komarova, Proteomic Analysis Uncovers Measles Virus Protein C Interaction With p65–iASPP Protein Complex, Molecular and Cellular Proteomics, 2021, 20, pp.100049. ⟨10.1016/j.mcpro.2021.100049⟩.
• 2020
  Guillaume Beauclair, Felix Streicher, Maxime Chazal, Daniela Bruni, Sarah Lesage, Ségolène Gracias, Salomé Bourgeau, Laura Sinigaglia, Takashi Fujita, Eliane Meurs, Frédéric Tangy, Nolwenn Jouvenet, Retinoic Acid Inducible Gene I and Protein Kinase R, but Not Stress Granules, Mediate the Proinflammatory Response to Yellow Fever Virus, Journal of Virology, 2020, 94 (22), pp.e00403-20. ⟨10.1128/JVI.00403-20⟩.
• 2019
  Petrova E, Gracias S, Beauclair G, Tangy F, Jouvenet N, , Uncovering Flavivirus Host Dependency Factors through a Genome-Wide Gain-of-Function Screen., Viruses 2019 01; 11(1): .
• 2018
  Beauclair G, Mura M, Combredet C, Tangy F, Jouvenet N, Komarova AV, , DI-tector: defective interfering viral genomes’ detector for next-generation sequencing data., RNA 2018 10; 24(10): 1285-1296.
• 2018
  Chazal M, Beauclair G, Gracias S, Najburg V, Simon-Lorière E, Tangy F, Komarova AV, Jouvenet N, RIG-I Recognizes the 5′ Region of Dengue and Zika Virus Genomes., Cell Rep. 2018 Jul 10;24(2):320-328.
• 2017
  Lucas-Hourani M, Dauzonne D, Munier-Lehmann H, Khiar S, Nisole S, Dairou J, Helynck O, Afonso PV, Tangy F, Vidalain PO, Original chemical series of pyrimidine biosynthesis inhibitors that boost the antiviral interferon response, Antimicrob Agents Chemother. 2017 Sep 22;61(10). pii: e00383-17.
• 2016
  Achard C, Guillerme JB, Bruni D, Boisgerault N, Combredet C, Tangy F, Jouvenet N, Grégoire M, Fonteneau JF, Oncolytic measles virus induces tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated cytotoxicity by human myeloid and plasmacytoid dendritic cells., Oncoimmunology. 2016 Nov 18;6(1):e1261240.
• 2016
  Sanchez David RY, Combredet C, Sismeiro O, Dillies MA, Jagla B, Coppée JY, Mura M, Guerbois Galla M, Despres P, Tangy F, Komarova AV, Comparative analysis of viral RNA signatures on different RIG-I-like receptors, Elife 2016 Mar;5.
• 2015
  Lucas-Hourani M, Munier-Lehmann H, El Mazouni F, Malmquist NA, Harpon J, Coutant EP, Guillou S, Helynck O, Noel A, Scherf A, Phillips MA, Tangy F, Vidalain PO, Janin YL, Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH), J. Med. Chem. 2015 Jul;58(14):5579-98.
• 2015
  Ramsauer K, Schwameis M, Firbas C, Müllner M, Putnak RJ, Thomas SJ, Desprès P, Tauber E, Jilma B, Tangy F, Immunogenicity, safety, and tolerability of a recombinant measles-virus-based chikungunya vaccine: a randomised, double-blind, placebo-controlled, active-comparator, first-in-man trial, Lancet Infect Dis 2015 May;15(5):519-27.
• 2015
  Munier-Lehmann H, Lucas-Hourani M, Guillou S, Helynck O, Zanghi G, Noel A, Tangy F, Vidalain PO, Janin YL, Original 2-(3-alkoxy-1H-pyrazol-1-yl)pyrimidine derivatives as inhibitors of human dihydroorotate dehydrogenase (DHODH), J. Med. Chem. 2015 Jan;58(2):860-77.
• 2015
  Vidalain PO, Jacob Y, Hagemeijer MC, Jones LM, Neveu G, Roussarie JP, Rottier PJ, Tangy F, de Haan CA, A field-proven yeast two-hybrid protocol used to identify coronavirus-host protein-protein interactions, Methods Mol. Biol. 2015;1282:213-29.
• 2014
  Grandin C, Lucas-Hourani M, Clavel M, Taborik F, Vabret A, Tangy F, Contamin H, Vidalain PO, Evidence for an intranasal immune response to human respiratory syncytial virus infection in cynomolgus macaques, J. Gen. Virol. 2015 Apr;96(Pt 4):782-92.
• 2014
  Melia MM, Earle JP, Abdullah H, Reaney K, Tangy F, Cosby SL, Use of SLAM and PVRL4 and identification of pro-HB-EGF as cell entry receptors for wild type phocine distemper virus, PLoS ONE 2014;9(8):e106281.
• 2014
  Lucas-Hourani M, Munier-Lehmann H, Helynck O, Komarova A, Desprès P, Tangy F, Vidalain PO, High-throughput screening for broad-spectrum chemical inhibitors of RNA viruses, J Vis Exp 2014;(87).
• 2014
  Escriou N, Callendret B, Lorin V, Combredet C, Marianneau P, Février M, Tangy F, Protection from SARS coronavirus conferred by live measles vaccine expressing the spike glycoprotein, Virology 2014 Mar;452-453:32-41.
• 2014
  Jacob D, Ruffie C, Dubois M, Combredet C, Amino R, Formaglio P, Gorgette O, Pehau-Arnaudet G, Guery C, Puijalon O, Barale JC, Ménard R, Tangy F, Sala M, Whole Pichia pastoris yeast expressing measles virus nucleoprotein as a production and delivery system to multimerize Plasmodium antigens., PLoS One 2014 ; 9(1): e86658.
• 2013
  Tangy F, Desprès P, Yellow fever vaccine attenuation revealed: loss of diversity, J. Infect. Dis. 2014 Feb;209(3):318-20.
• 2013
  Lucas-Hourani M, Dauzonne D, Jorda P, Cousin G, Lupan A, Helynck O, Caignard G, Janvier G, André-Leroux G, Khiar S, Escriou N, Desprès P, Jacob Y, Munier-Lehmann H, Tangy F, Vidalain PO, Inhibition of pyrimidine biosynthesis pathway suppresses viral growth through innate immunity, PLoS Pathog. 2013;9(10):e1003678.
• 2013
  Brandler S, Tangy F, Vaccines in development against West Nile virus, Viruses 2013 Oct;5(10):2384-409.
• 2013
  Téoulé F, Brisac C, Pelletier I, Vidalain PO, Jégouic S, Mirabelli C, Bessaud M, Combelas N, Autret A, Tangy F, Delpeyroux F, Blondel B, The Golgi protein ACBD3, an interactor for poliovirus protein 3A, modulates poliovirus replication, J. Virol. 2013 Oct;87(20):11031-46.
• 2013
  Brandler S, Ruffié C, Combredet C, Brault JB, Najburg V, Prevost MC, Habel A, Tauber E, Desprès P, Tangy F, A recombinant measles vaccine expressing chikungunya virus-like particles is strongly immunogenic and protects mice from lethal challenge with chikungunya virus, Vaccine 2013 Aug;31(36):3718-25.
• 2013
  Judith D, Mostowy S, Bourai M, Gangneux N, Lelek M, Lucas-Hourani M, Cayet N, Jacob Y, Prévost MC, Pierre P, Tangy F, Zimmer C, Vidalain PO, Couderc T, Lecuit M, , Species-specific impact of the autophagy machinery on Chikungunya virus infection., EMBO Rep 2013 Jun; 14(6): 534-44.
• 2013
  Komarova AV, Combredet C, Sismeiro O, Dillies MA, Jagla B, Sanchez David RY, Vabret N, Coppée JY, Vidalain PO, Tangy F, Identification of RNA partners of viral proteins in infected cells, RNA Biol 2013 Jun;10(6):944-56.
• 2013
  Guillerme JB, Gregoire M, Tangy F, Fonteneau JF, Antitumor Virotherapy by Attenuated Measles Virus (MV), Biology (Basel) 2013;2(2):587-602.
• 2013
  Munier-Lehmann H, Vidalain PO, Tangy F, Janin YL, On dihydroorotate dehydrogenases and their inhibitors and uses, J. Med. Chem. 2013 Apr;56(8):3148-67.
• 2013
  Caignard G, Lucas-Hourani M, Dhondt KP, Labernardière JL, Petit T, Jacob Y, Horvat B, Tangy F, Vidalain PO, The V protein of Tioman virus is incapable of blocking type I interferon signaling in human cells, PLoS ONE 2013;8(1):e53881.
• 2012
  Luco S, Delmas O, Vidalain PO, Tangy F, Weil R, Bourhy H, RelAp43, a member of the NF-κB family involved in innate immune response against Lyssavirus infection, PLoS Pathog. 2012;8(12):e1003060.
• 2012
  Lucas-Hourani M, Lupan A, Desprès P, Thoret S, Pamlard O, Dubois J, Guillou C, Tangy F, Vidalain PO, Munier-Lehmann H, A phenotypic assay to identify Chikungunya virus inhibitors targeting the nonstructural protein nsP2, J Biomol Screen 2013 Feb;18(2):172-9.
• 2012
  Aynaud MM, Suspène R, Vidalain PO, Mussil B, Guétard D, Tangy F, Wain-Hobson S, Vartanian JP, Human Tribbles 3 protects nuclear DNA from cytidine deamination by APOBEC3A, J. Biol. Chem. 2012 Nov;287(46):39182-92.
• 2012
  Neveu G, Cassonnet P, Vidalain PO, Rolloy C, Mendoza J, Jones L, Tangy F, Muller M, Demeret C, Tafforeau L, Lotteau V, Rabourdin-Combe C, Travé G, Dricot A, Hill DE, Vidal M, Favre M, Jacob Y, Comparative analysis of virus-host interactomes with a mammalian high-throughput protein complementation assay based on Gaussia princeps luciferase, Methods 2012 Dec;58(4):349-59.
• 2012
  Mesel-Lemoine M, Millet J, Vidalain PO, Law H, Vabret A, Lorin V, Escriou N, Albert ML, Nal B, Tangy F, A human coronavirus responsible for the common cold massively kills dendritic cells but not monocytes, J. Virol. 2012 Jul;86(14):7577-87.
• 2012
  Brandler S, Marianneau P, Loth P, Lacôte S, Combredet C, Frenkiel MP, Desprès P, Contamin H, Tangy F, Measles vaccine expressing the secreted form of West Nile virus envelope glycoprotein induces protective immunity in squirrel monkeys, a new model of West Nile virus infection, J. Infect. Dis. 2012 Jul;206(2):212-9.
• 2012
  Bouraï M, Lucas-Hourani M, Gad HH, Drosten C, Jacob Y, Tafforeau L, Cassonnet P, Jones LM, Judith D, Couderc T, Lecuit M, André P, Kümmerer BM, Lotteau V, Desprès P, Tangy F, Vidalain PO, , Mapping of Chikungunya virus interactions with host proteins identified nsP2 as a highly connected viral component., J Virol 2012 Mar; 86(6): 3121-34.
• 2011
  Komarova AV, Combredet C, Meyniel-Schicklin L, Chapelle M, Caignard G, Camadro JM, Lotteau V, Vidalain PO, Tangy F, Proteomic analysis of virus-host interactions in an infectious context using recombinant viruses, Mol. Cell Proteomics 2011 Dec;10(12):M110.007443.
• 2011
  Mourez T, Mesel-Lemoine M, Combredet C, Najburg V, Cayet N, Tangy F, A chimeric measles virus with a lentiviral envelope replicates exclusively in CD4+/CCR5+ cells, Virology 2011 Oct;419(2):117-25.
• 2011
  Brault JB, Kudelko M, Vidalain PO, Tangy F, Desprès P, Pardigon N, The interaction of flavivirus M protein with light chain Tctex-1 of human dynein plays a role in late stages of virus replication, Virology 2011 Sep;417(2):369-78.
• 2010
  Vidalain PO, Tangy F, Virus-host protein interactions in RNA viruses, Microbes Infect. 2010 Dec;12(14-15):1134-43.
• 2010
  Brandler S, Ruffie C, Najburg V, Frenkiel MP, Bedouelle H, Desprès P, Tangy F, Pediatric measles vaccine expressing a dengue tetravalent antigen elicits neutralizing antibodies against all four dengue viruses, Vaccine 2010 Sep;28(41):6730-9.
• 2010
  Pelletier I, Saulnier A, Brisac C, Jegouic S, Vabret N, Tangy F, Blondel B, Colbère-Garapin F, Enhanced gene silencing in cells cured of persistent virus infection by RNA interference, J. Virol. 2010 Jul;84(13):6880-5.
• 2009
  Assenberg R, Delmas O, Ren J, Vidalain PO, Verma A, Larrous F, Graham SC, Tangy F, Grimes JM, Bourhy H, Structure of the nucleoprotein binding domain of Mokola virus phosphoprotein, J. Virol. 2010 Jan;84(2):1089-96.
• 2009
  Pothlichet J, Burtey A, Kubarenko AV, Caignard G, Solhonne B, Tangy F, Ben-Ali M, Quintana-Murci L, Heinzmann A, Chiche JD, Vidalain PO, Weber AN, Chignard M, Si-Tahar M, Study of human RIG-I polymorphisms identifies two variants with an opposite impact on the antiviral immune response, PLoS ONE 2009;4(10):e7582.
• 2009
  Caignard G, Komarova AV, Bouraï M, Mourez T, Jacob Y, Jones LM, Rozenberg F, Vabret A, Freymuth F, Tangy F, Vidalain PO, Differential regulation of type I interferon and epidermal growth factor pathways by a human Respirovirus virulence factor, PLoS Pathog. 2009 Sep;5(9):e1000587.
• 2009
  Journo C, Filipe J, About F, Chevalier SA, Afonso PV, Brady JN, Flynn D, Tangy F, Israël A, Vidalain PO, Mahieux R, Weil R, NRP/Optineurin Cooperates with TAX1BP1 to potentiate the activation of NF-kappaB by human T-lymphotropic virus type 1 tax protein, PLoS Pathog. 2009 Jul;5(7):e1000521.
• 2009
  Vitour D, Dabo S, Ahmadi Pour M, Vilasco M, Vidalain PO, Jacob Y, Mezel-Lemoine M, Paz S, Arguello M, Lin R, Tangy F, Hiscott J, Meurs EF, Polo-like kinase 1 (PLK1) regulates interferon (IFN) induction by MAVS, J. Biol. Chem. 2009 Aug;284(33):21797-809.
• 2009
  Guerbois M, Moris A, Combredet C, Najburg V, Ruffié C, Février M, Cayet N, Brandler S, Schwartz O, Tangy F, Live attenuated measles vaccine expressing HIV-1 Gag virus like particles covered with gp160DeltaV1V2 is strongly immunogenic, Virology 2009 May;388(1):191-203.
• 2008
  Caignard G, Bouraï M, Jacob Y, , Tangy F, Vidalain PO, Inhibition of IFN-alpha/beta signaling by two discrete peptides within measles virus V protein that specifically bind STAT1 and STAT2, Virology 2009 Jan;383(1):112-20.
• 2008
  Ozden S, Lucas-Hourani M, Ceccaldi PE, Basak A, Valentine M, Benjannet S, Hamelin J, Jacob Y, Mamchaoui K, Mouly V, Desprès P, Gessain A, Butler-Browne G, Chrétien M, Tangy F, Vidalain PO, Seidah NG, Inhibition of Chikungunya virus infection in cultured human muscle cells by furin inhibitors: impairment of the maturation of the E2 surface glycoprotein, J. Biol. Chem. 2008 Aug;283(32):21899-908.
• 2008
  Suspène R, Renard M, Henry M, Guétard D, Puyraimond-Zemmour D, Billecocq A, Bouloy M, Tangy F, Vartanian JP, Wain-Hobson S, Inversing the natural hydrogen bonding rule to selectively amplify GC-rich ADAR-edited RNAs, Nucleic Acids Res. 2008 Jul;36(12):e72.
• 2007
  Brandler S, Lucas-Hourani M, Moris A, Frenkiel MP, Combredet C, Février M, Bedouelle H, Schwartz O, Desprès P, Tangy F, Pediatric measles vaccine expressing a dengue antigen induces durable serotype-specific neutralizing antibodies to dengue virus, PLoS Negl Trop Dis 2007;1(3):e96.
• 2007
  Brandler S, Tangy F, Recombinant vector derived from live attenuated measles virus: potential for flavivirus vaccines, Comp. Immunol. Microbiol. Infect. Dis. 2008 Mar;31(2-3):271-91.
• 2007
  Caignard G, Guerbois M, Labernardière JL, Jacob Y, Jones LM, , Wild F, Tangy F, Vidalain PO, Measles virus V protein blocks Jak1-mediated phosphorylation of STAT1 to escape IFN-alpha/beta signaling, Virology 2007 Nov;368(2):351-62.
• 2005
  Lorin C, Delebecque F, Labrousse V, Da Silva L, Lemonnier F, Brahic M, Tangy F, A recombinant live attenuated measles vaccine vector primes effective HLA-A0201-restricted cytotoxic T lymphocytes and broadly neutralizing antibodies against HIV-1 conserved epitopes, Vaccine 2005 Aug;23(36):4463-72.
• 2005
  Lorin C, Combredet C, Labrousse V, Mollet L, Desprès P, Tangy F, A paediatric vaccination vector based on live attenuated measles vaccine, Therapie 2005 May-Jun;60(3):227-33.
• 2005
  Lorin C, Saidi H, Belaid A, Zairi A, Baleux F, Hocini H, Bélec L, Hani K, Tangy F, The antimicrobial peptide dermaseptin S4 inhibits HIV-1 infectivity in vitro, Virology 2005 Apr;334(2):264-75.
• 2005
  Tangy F, Naim HY, Live attenuated measles vaccine as a potential multivalent pediatric vaccination vector, Viral Immunol. 2005;18(2):317-26.
• 2004
  F. Delebecque, C. Combredet, As Gabet, E. Wattel, M. Brahic, F. Tangy, A chimeric human T cell leukemia virus type I bearing a deltaR Moloney-murine leukemia virus envelope infects mice persistently and induces humoral and cellular immune responses., Journal of Infectious Diseases, 2005, pp.263. ⟨10.1086/426825⟩.
• 2004
  Desprès P, Combredet C, Frenkiel MP, Lorin C, Brahic M, Tangy F, Live measles vaccine expressing the secreted form of the West Nile virus envelope glycoprotein protects against West Nile virus encephalitis, J. Infect. Dis. 2005 Jan;191(2):207-14.
• 2004
  Lorin C, Mollet L, Delebecque F, Combredet C, Hurtrel B, Charneau P, Brahic M, Tangy F, A single injection of recombinant measles virus vaccines expressing human immunodeficiency virus (HIV) type 1 clade B envelope glycoproteins induces neutralizing antibodies and cellular immune responses to HIV, J. Virol. 2004 Jan;78(1):146-57.
• 2002
  Delebecque F, Pramberger K, Prévost MC, Brahic M, Tangy F, A chimeric human T-cell lymphotropic virus type 1 with the envelope glycoprotein of Moloney murine leukemia virus is infectious for murine cells, J. Virol. 2002 Aug;76(15):7883-9.