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Guides
  • 2024
    Richard E, Darracq B, Littner E, Millot GA, Conte V, Cokelaer T, Engelstädter J, Rocha EPC, Mazel D, Loot C, Belt and braces: Two escape ways to maintain the cassette reservoir of large chromosomal integrons., PLoS Genet 2024 Apr; 20(4): e1011231.
  • 2024
    Egill Richard, Baptiste Darracq, Eloi Littner, Claire Vit, Clémence Whiteway, Julia Bos, Florian Fournes, Geneviève Garriss, Valentin Conte, Delphine Lapaillerie, Vincent Parissi, François Rousset, Ole Skovgaard, David Bikard, Eduardo P. C. Rocha, Didier Mazel, Céline Loot, Cassette recombination dynamics within chromosomal integrons are regulated by toxin-antitoxin systems., Science Advances , 2024, 10 (2), pp.eadj3498. ⟨10.1126/sciadv.adj3498⟩.
  • 2024
    Loot C, Millot GA, Richard E, Littner E, Vit C, Lemoine F, Néron B, Cury J, Darracq B, Niault T, Lapaillerie D, Parissi V, Rocha EPC, Mazel D, Integron cassettes integrate into bacterial genomes via widespread non-classical attG sites., Nat Microbiol 2024 Jan; 9(1): 228-240.
  • 2022
    Richard E, Darracq B, Loot C, Mazel D, Unbridled Integrons: A Matter of Host Factors., Cells 2022 Mar; 11(6): .
  • 2021
    Vit C, Richard E, Fournes F, Whiteway C, Eyer X, Lapaillerie D, Parissi V, Mazel D, Loot C, Cassette recruitment in the chromosomal Integron of Vibrio cholerae., Nucleic Acids Res 2021 Jun; 49(10): 5654-5670.
  • 2020
    Escudero JA, Nivina A, Kemble HE, Loot C, Tenaillon O, Mazel D, Primary and promiscuous functions coexist during evolutionary innovation through whole protein domain acquisitions., Elife 2020 Dec; 9(): .
  • 2020
    Aleksandra Nivina, Maj Svea Grieb, Céline Loot, David Bikard, Jean Cury, Laila Shehata, Juliana Bernardes, Didier Mazel, Structure-specific DNA recombination sites: Design, validation, and machine learning–based refinement, Science Advances , 2020, 6 (30), pp.eaay2922. ⟨10.1126/sciadv.aay2922⟩.
  • 2020
    Vit C, Loot C, Escudero JA, Nivina A, Mazel D, Integron Identification in Bacterial Genomes and Cassette Recombination Assays., Methods Mol Biol 2020 ; 2075(): 189-208.
  • 2019
    Mukhortava A, Pöge M, Grieb MS, Nivina A, Loot C, Mazel D, Schlierf M, Structural heterogeneity of attC integron recombination sites revealed by optical tweezers., Nucleic Acids Res 2019 Feb; 47(4): 1861-1870.
  • 2018
    Escudero JA, Nivina A, Cambray G, López-Igual R, Loot C, Mazel D, Recoding of synonymous genes to expand evolutionary landscapes requires control of secondary structure affecting translation., Biotechnol Bioeng 2018 Jan; 115(1): 184-191.
  • 2017
    Céline Loot, Aleksandra Nivina, Jean Cury, José Antonio Escudero, Magaly Ducos-Galand, David Bikard, Eduardo P C Rocha, Didier Mazel, Differences in Integron Cassette Excision Dynamics Shape a Trade-Off between Evolvability and Genetic Capacitance., mBio, 2017, 8 (2), pp.e02296-16. ⟨10.1128/mBio.02296-16⟩.
  • 2016
    Nivina A, Escudero JA, Vit C, Mazel D, Loot C, Efficiency of integron cassette insertion in correct orientation is ensured by the interplay of the three unpaired features of attC recombination sites., Nucleic Acids Res 2016 Sep; 44(16): 7792-803.
  • 2016
    Rey O, Danchin E, Mirouze M, Loot C, Blanchet S, Adaptation to Global Change: A Transposable Element-Epigenetics Perspective., Trends Ecol Evol 2016 Jul; 31(7): 514-526.
  • 2016
    Escudero JA, Loot C, Parissi V, Nivina A, Bouchier C, Mazel D, Unmasking the ancestral activity of integron integrases reveals a smooth evolutionary transition during functional innovation., Nat Commun 2016 Mar; 7(): 10937.
  • 2015
    Escudero JA, Loot C, Nivina A, Mazel D, The Integron: Adaptation On Demand., Microbiol Spectr 2015 Apr; 3(2): MDNA3-0019-2014.
  • 2014
    Loot C, Parissi V, Escudero JA, Amarir-Bouhram J, Bikard D, Mazel D, The integron integrase efficiently prevents the melting effect of Escherichia coli single-stranded DNA-binding protein on folded attC sites., J Bacteriol 2014 Feb; 196(4): 762-71.
  • 2012
    Loot C, Ducos-Galand M, Escudero JA, Bouvier M, Mazel D, Replicative resolution of integron cassette insertion., Nucleic Acids Res 2012 Sep; 40(17): 8361-70.
  • 2010
    Bikard D, Loot C, Baharoglu Z, Mazel D, Folded DNA in action: hairpin formation and biological functions in prokaryotes., Microbiol Mol Biol Rev 2010 Dec; 74(4): 570-88.
  • 2010
    Loot C, Bikard D, Rachlin A, Mazel D, Cellular pathways controlling integron cassette site folding., EMBO J 2010 Aug; 29(15): 2623-34.
  • 2009
    Bouvier M, Ducos-Galand M, Loot C, Bikard D, Mazel D, Structural features of single-stranded integron cassette attC sites and their role in strand selection., PLoS Genet 2009 Sep; 5(9): e1000632.
  • 2008
    Guermonprez H, Loot C, Casacuberta JM, Different strategies to persist: the pogo-like Lemi1 transposon produces miniature inverted-repeat transposable elements or typical defective elements in different plant genomes., Genetics 2008 Sep; 180(1): 83-92.
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