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2019Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling, Sci Signal 2019 05;12(580).
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2019Novel mechanistic insights into physiological signaling pathways mediated by mycobacterial Ser/Thr protein kinases, Genes Immun. 2019 Apr;.
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2017PknG senses amino acid availability to control metabolism and virulence of Mycobacterium tuberculosis, PLoS Pathog. 2017 May;13(5):e1006399.
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2015Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG, Chem. Biol. 2015 Jul;22(7):917-27.
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2015The crystal structure of the catalytic domain of the ser/thr kinase PknA from M. tuberculosis shows an Src-like autoinhibited conformation, Proteins 2015 May;83(5):982-8.
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2014Secondary structure reshuffling modulates glycosyltransferase function at the membrane, Nat. Chem. Biol. 2015 Jan;11(1):16-8.
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2014Structural studies suggest a peptidoglycan hydrolase function for the Mycobacterium tuberculosis Tat-secreted protein Rv2525c, J. Struct. Biol. 2014 Nov;188(2):156-64.
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2014A dual conformation of the post-decarboxylation intermediate is associated with distinct enzyme states in mycobacterial KGD (α-ketoglutarate decarboxylase), Biochem. J. 2014 Feb;457(3):425-34.
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2013GarA is an essential regulator of metabolism in Mycobacterium tuberculosis, Mol. Microbiol. 2013 Oct;90(2):356-66.
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2013Tolerance of the archaeal Sac7d scaffold protein to alternative library designs: characterization of anti-immunoglobulin G Affitins, Protein Eng. Des. Sel. 2013 Apr;26(4):267-75.
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2013Contactin 4, -5 and -6 differentially regulate neuritogenesis while they display identical PTPRG binding sites, Biol Open 2013 Mar;2(3):324-34.
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2012Conformational changes upon ligand binding in the essential class II fumarase Rv1098c from Mycobacterium tuberculosis, FEBS Lett. 2012 Jun;586(11):1606-11.
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2011Functional plasticity and allosteric regulation of α-ketoglutarate decarboxylase in central mycobacterial metabolism, Chem. Biol. 2011 Aug;18(8):1011-20.
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20113-Keto-5-aminohexanoate cleavage enzyme: a common fold for an uncommon Claisen-type condensation, J. Biol. Chem. 2011 Aug;286(31):27399-405.
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2010Biological and structural characterization of the Mycobacterium smegmatis nitroreductase NfnB, and its role in benzothiazinone resistance, Mol. Microbiol. 2010 Sep;77(5):1172-85.
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2010A novel role of malonyl-ACP in lipid homeostasis, Biochemistry 2010 Apr;49(14):3161-7.
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2010Crystal structure of Mycobacterium tuberculosis LppA, a lipoprotein confined to pathogenic mycobacteria, Proteins 2010 Feb;78(3):769-72.
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2009Structural plasticity and distinct drug-binding modes of LfrR, a mycobacterial efflux pump regulator, J. Bacteriol. 2009 Dec;191(24):7531-7.
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2009Structure of Mycobacterium tuberculosis Rv2714, a representative of a duplicated gene family in Actinobacteria, Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 2009 Oct;65(Pt 10):972-7.
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2009Bacterial metabolism under FHA control, Structure 2009 Apr;17(4):487-8.
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2008Regulation of glutamate metabolism by protein kinases in mycobacteria, Mol. Microbiol. 2008 Dec;70(6):1408-23.
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2007Structural and binding studies of the three-metal center in two mycobacterial PPM Ser/Thr protein phosphatases, J. Mol. Biol. 2007 Dec;374(4):890-8.
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2007Mycobacterial Ser/Thr protein kinases and phosphatases: physiological roles and therapeutic potential, Biochim. Biophys. Acta 2008 Jan;1784(1):193-202.
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2007Insights into the catalytic mechanism of PPM Ser/Thr phosphatases from the atomic resolution structures of a mycobacterial enzyme, Structure 2007 Jul;15(7):863-72.
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2006The crystal structure of Mycobacterium tuberculosis adenylate kinase in complex with two molecules of ADP and Mg2+ supports an associative mechanism for phosphoryl transfer, Protein Sci. 2006 Jun;15(6):1489-93.
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2006The structure of PknB in complex with mitoxantrone, an ATP-competitive inhibitor, suggests a mode of protein kinase regulation in mycobacteria, FEBS Lett. 2006 May;580(13):3018-22.
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2005Conserved autophosphorylation pattern in activation loops and juxtamembrane regions of Mycobacterium tuberculosis Ser/Thr protein kinases, Biochem. Biophys. Res. Commun. 2005 Aug;333(3):858-67.
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2005Glutamine amidotransferase activity of NAD+ synthetase from Mycobacterium tuberculosis depends on an amino-terminal nitrilase domain, Res. Microbiol. 2005 Mar;156(2):173-7.
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2004Rv2686c-Rv2687c-Rv2688c, an ABC fluoroquinolone efflux pump in Mycobacterium tuberculosis, Antimicrob. Agents Chemother. 2004 Aug;48(8):3175-8.
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2003Techniques and applications: The heterologous expression of Mycobacterium tuberculosis genes is an uphill road, Trends Microbiol. 2003 Aug;11(8):351-8.
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2003The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology, Tuberculosis (Edinb) 2003;83(4):223-49.
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2002The multidrug transporters belonging to major facilitator superfamily in Mycobacterium tuberculosis, Mol. Med. 2002 Nov;8(11):714-24.
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2002Reconstitution of T-cell receptor repertoire diversity following non-myeloablative allogeneic stem cell transplantation in an acute myeloid leukemia patient, Haematologica 2002 Oct;87(10):ECR31.
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2002High prevalence of a variant of SENV in intravenous drug user HIV-infected patients, J. Med. Virol. 2002 Sep;68(1):18-23.
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2002Heterologous expression, purification, and enzymatic activity of Mycobacterium tuberculosis NAD(+) synthetase, Protein Expr. Purif. 2002 Aug;25(3):547-57.
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2002Transmission of SEN virus from mothers to their babies, J. Med. Virol. 2002 Mar;66(3):421-7.