• 2021
  Bruch EM, Vilela P, Yang L, Boyko A, Lexa-Sapart N, Raynal B, Alzari PM, Bellinzoni M, , Actinobacteria challenge the paradigm: A unique protein architecture for a well-known, central metabolic complex., Proc Natl Acad Sci U S A 2021 Nov; 118(48): .
• 2021
  Lisa MN, Sogues A, Barilone N, Baumgart M, Gil M, Graña M, Durán R, Biondi RM, Bellinzoni M, Bott M, Alzari PM, , A Tetratricopeptide Repeat Scaffold Couples Signal Detection to OdhI Phosphorylation in Metabolic Control by the Protein Kinase PknG., mBio 2021 Oct; 12(5): e0171721.
• 2021
  Lima A, Leyva A, Rivera B, Portela MM, Gil M, Cascioferro A, Lisa MN, Wehenkel A, Bellinzoni M, Carvalho PC, Batthyány C, Alvarez MN, Brosch R, Alzari PM, Durán R, , Proteome remodeling in the Mycobacterium tuberculosis PknG knockout: Molecular evidence for the role of this kinase in cell envelope biogenesis and hypoxia response., J Proteomics 2021 07; 244(): 104276.
• 2020
  Mori M, Stelitano G, Gelain A, Pini E, Chiarelli LR, Sammartino JC, Poli G, Tuccinardi T, Beretta G, Porta A, Bellinzoni M, Villa S, Meneghetti F, , Shedding X-ray Light on the Role of Magnesium in the Activity of Mycobacterium tuberculosis Salicylate Synthase (MbtI) for Drug Design., J Med Chem 2020 07; 63(13): 7066-7080.
• 2020
  Bruch, E.M., Petrella, S., Bellinzoni, M., Structure-Based Drug Design for Tuberculosis: Challenges Still Ahead, Appl. Sci. 2020; 10(12):4248.
• 2020
  Artiukhov AV, Kazantsev AV, Lukashev NV, Bellinzoni M, Bunik VI, , Selective Inhibition of 2-Oxoglutarate and 2-Oxoadipate Dehydrogenases by the Phosphonate Analogs of Their 2-Oxo Acid Substrates., Front Chem 2020 ; 8(): 596187.
• 2019
  Chiarelli LR, Mori M, Beretta G, Gelain A, Pini E, Sammartino JC, Stelitano G, Barlocco D, Costantino L, Lapillo M, Poli G, Caligiuri I, Rizzolio F, Bellinzoni M, Tuccinardi T, Villa S, Meneghetti F, , New insight into structure-activity of furan-based salicylate synthase (MbtI) inhibitors as potential antitubercular agents., J Enzyme Inhib Med Chem 2019 Dec; 34(1): 823-828.
• 2019
  Wagner T, Boyko A, Alzari PM, Bunik VI, Bellinzoni M, , Conformational transitions in the active site of mycobacterial 2-oxoglutarate dehydrogenase upon binding phosphonate analogues of 2-oxoglutarate: From a Michaelis-like complex to ThDP adducts., J Struct Biol 2019 11; 208(2): 182-190.
• 2019
  Bellinzoni M, Wehenkel AM, Durán R, Alzari PM, , Novel mechanistic insights into physiological signaling pathways mediated by mycobacterial Ser/Thr protein kinases., Microbes Infect ; 21(5-6): 222-229.
• 2019
  Wagner T, André-Leroux G, Hindie V, Barilone N, Lisa MN, Hoos S, Raynal B, Vulliez-Le Normand B, O'Hare HM, Bellinzoni M, Alzari PM, , Structural insights into the functional versatility of an FHA domain protein in mycobacterial signaling., Sci Signal 2019 05; 12(580): .
• 2019
  Bellinzoni M, Wehenkel AM, Durán R, Alzari PM, , Novel mechanistic insights into physiological signaling pathways mediated by mycobacterial Ser/Thr protein kinases., Genes Immun 2019 05; 20(5): 383-393.
• 2019
  Gil M, Lima A, Rivera B, Rossello J, Urdániz E, Cascioferro A, Carrión F, Wehenkel A, Bellinzoni M, Batthyány C, Pritsch O, Denicola A, Alvarez MN, Carvalho PC, Lisa MN, Brosch R, Piuri M, Alzari PM, Durán R, , New substrates and interactors of the mycobacterial Serine/Threonine protein kinase PknG identified by a tailored interactomic approach., J Proteomics 2019 02; 192(): 321-333.
• 2017
  Rieck B, Degiacomi G, Zimmermann M, Cascioferro A, Boldrin F, Lazar-Adler NR, Bottrill AR, le Chevalier F, Frigui W, Bellinzoni M, Lisa MN, Alzari PM, Nguyen L, Brosch R, Sauer U, Manganelli R, O'Hare HM, , PknG senses amino acid availability to control metabolism and virulence of Mycobacterium tuberculosis., PLoS Pathog 2017 May; 13(5): e1006399.
• 2017
  Lisa MN, Wagner T, Alexandre M, Barilone N, Raynal B, Alzari PM, Bellinzoni M, , The crystal structure of PknI from Mycobacterium tuberculosis shows an inactive, pseudokinase-like conformation., FEBS J 2017 02; 284(4): 602-614.
• 2016
  Le NH, Molle V, Eynard N, Miras M, Stella A, Bardou F, Galandrin S, Guillet V, André-Leroux G, Bellinzoni M, Alzari P, Mourey L, Burlet-Schiltz O, Daffé M, Marrakchi H, , Ser/Thr Phosphorylation Regulates the Fatty Acyl-AMP Ligase Activity of FadD32, an Essential Enzyme in Mycolic Acid Biosynthesis., J Biol Chem 2016 Oct; 291(43): 22793-22805.
• 2015
  Mori G, Chiarelli LR, Esposito M, Makarov V, Bellinzoni M, Hartkoorn RC, Degiacomi G, Boldrin F, Ekins S, de Jesus Lopes Ribeiro AL, Marino LB, Centárová I, Svetlíková Z, Blaško J, Kazakova E, Lepioshkin A, Barilone N, Zanoni G, Porta A, Fondi M, Fani R, Baulard AR, Mikušová K, Alzari PM, Manganelli R, de Carvalho LP, Riccardi G, Cole ST, Pasca MR, , Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG., Chem Biol 2015 Jul; 22(7): 917-27.
• 2015
  Wagner T, Alexandre M, Duran R, Barilone N, Wehenkel A, Alzari PM, Bellinzoni M, , The crystal structure of the catalytic domain of the ser/thr kinase PknA from M. tuberculosis shows an Src-like autoinhibited conformation., Proteins 2015 May; 83(5): 982-8.
• 2014
  Giganti D, Albesa-Jové D, Urresti S, Rodrigo-Unzueta A, Martínez MA, Comino N, Barilone N, Bellinzoni M, Chenal A, Guerin ME, Alzari PM, , Secondary structure reshuffling modulates glycosyltransferase function at the membrane., Nat Chem Biol 2015 Jan; 11(1): 16-8.
• 2014
  Bellinzoni M, Haouz A, Miras I, Magnet S, André-Leroux G, Mukherjee R, Shepard W, Cole ST, Alzari PM, , Structural studies suggest a peptidoglycan hydrolase function for the Mycobacterium tuberculosis Tat-secreted protein Rv2525c., J Struct Biol 2014 Nov; 188(2): 156-64.
• 2014
  Wagner T, Barilone N, Alzari PM, Bellinzoni M, , A dual conformation of the post-decarboxylation intermediate is associated with distinct enzyme states in mycobacterial KGD (α-ketoglutarate decarboxylase)., Biochem J 2014 Feb; 457(3): 425-34.
• 2013
  Ventura M, Rieck B, Boldrin F, Degiacomi G, Bellinzoni M, Barilone N, Alzaidi F, Alzari PM, Manganelli R, O'Hare HM, , GarA is an essential regulator of metabolism in Mycobacterium tuberculosis., Mol Microbiol 2013 Oct; 90(2): 356-66.
• 2013
  Béhar G, Bellinzoni M, Maillasson M, Paillard-Laurance L, Alzari PM, He X, Mouratou B, Pecorari F, , Tolerance of the archaeal Sac7d scaffold protein to alternative library designs: characterization of anti-immunoglobulin G Affitins., Protein Eng Des Sel 2013 Apr; 26(4): 267-75.
• 2013
  Mercati O, Danckaert A, André-Leroux G, Bellinzoni M, Gouder L, Watanabe K, Shimoda Y, Grailhe R, De Chaumont F, Bourgeron T, Cloëz-Tayarani I, , Contactin 4, -5 and -6 differentially regulate neuritogenesis while they display identical PTPRG binding sites., Biol Open 2013 Mar; 2(3): 324-34.
• 2012
  Mechaly AE, Haouz A, Miras I, Barilone N, Weber P, Shepard W, Alzari PM, Bellinzoni M, , Conformational changes upon ligand binding in the essential class II fumarase Rv1098c from Mycobacterium tuberculosis., FEBS Lett 2012 Jun; 586(11): 1606-11.
• 2011
  Wagner T, Bellinzoni M, Wehenkel A, O'Hare HM, Alzari PM, , Functional plasticity and allosteric regulation of α-ketoglutarate decarboxylase in central mycobacterial metabolism., Chem Biol 2011 Aug; 18(8): 1011-20.
• 2011
  Bellinzoni M, Bastard K, Perret A, Zaparucha A, Perchat N, Vergne C, Wagner T, de Melo-Minardi RC, Artiguenave F, Cohen GN, Weissenbach J, Salanoubat M, Alzari PM, , 3-Keto-5-aminohexanoate cleavage enzyme: a common fold for an uncommon Claisen-type condensation., J Biol Chem 2011 Aug; 286(31): 27399-405.
• 2010
  Manina G, Bellinzoni M, Pasca MR, Neres J, Milano A, Ribeiro AL, Buroni S, Skovierová H, Dianišková P, Mikušová K, Marák J, Makarov V, Giganti D, Haouz A, Lucarelli AP, Degiacomi G, Piazza A, Chiarelli LR, De Rossi E, Salina E, Cole ST, Alzari PM, Riccardi G, , Biological and structural characterization of the Mycobacterium smegmatis nitroreductase NfnB, and its role in benzothiazinone resistance., Mol Microbiol 2010 Sep; 77(5): 1172-85.
• 2010
  Martinez MA, Zaballa ME, Schaeffer F, Bellinzoni M, Albanesi D, Schujman GE, Vila AJ, Alzari PM, de Mendoza D, , A novel role of malonyl-ACP in lipid homeostasis., Biochemistry 2010 Apr; 49(14): 3161-7.
• 2010
  Graña M, Bellinzoni M, Bellalou J, Haouz A, Miras I, Buschiazzo A, Winter N, Alzari PM, , Crystal structure of Mycobacterium tuberculosis LppA, a lipoprotein confined to pathogenic mycobacteria., Proteins 2010 Feb; 78(3): 769-72.
• 2009
  Bellinzoni M, Buroni S, Schaeffer F, Riccardi G, De Rossi E, Alzari PM, , Structural plasticity and distinct drug-binding modes of LfrR, a mycobacterial efflux pump regulator., J Bacteriol 2009 Dec; 191(24): 7531-7.
• 2009
  Graña M, Bellinzoni M, Miras I, Fiez-Vandal C, Haouz A, Shepard W, Buschiazzo A, Alzari PM, , Structure of Mycobacterium tuberculosis Rv2714, a representative of a duplicated gene family in Actinobacteria., Acta Crystallogr Sect F Struct Biol Cryst Commun 2009 Oct; 65(Pt 10): 972-7.
• 2009
  Bellinzoni M, Alzari PM, , Bacterial metabolism under FHA control., Structure 2009 Apr; 17(4): 487-8.
• 2008
  O'Hare HM, Durán R, Cerveñansky C, Bellinzoni M, Wehenkel AM, Pritsch O, Obal G, Baumgartner J, Vialaret J, Johnsson K, Alzari PM, , Regulation of glutamate metabolism by protein kinases in mycobacteria., Mol Microbiol 2008 Dec; 70(6): 1408-23.
• 2007
  Wehenkel A, Bellinzoni M, Schaeffer F, Villarino A, Alzari PM, , Structural and binding studies of the three-metal center in two mycobacterial PPM Ser/Thr protein phosphatases., J Mol Biol 2007 Dec; 374(4): 890-8.
• 2007
  Wehenkel A, Bellinzoni M, Graña M, Duran R, Villarino A, Fernandez P, Andre-Leroux G, England P, Takiff H, Cerveñansky C, Cole ST, Alzari PM, , Mycobacterial Ser/Thr protein kinases and phosphatases: physiological roles and therapeutic potential., Biochim Biophys Acta 2008 Jan; 1784(1): 193-202.
• 2007
  Bellinzoni M, Wehenkel A, Shepard W, Alzari PM, , Insights into the catalytic mechanism of PPM Ser/Thr phosphatases from the atomic resolution structures of a mycobacterial enzyme., Structure 2007 Jul; 15(7): 863-72.
• 2006
  Bellinzoni M, Haouz A, Graña M, Munier-Lehmann H, Shepard W, Alzari PM, , The crystal structure of Mycobacterium tuberculosis adenylate kinase in complex with two molecules of ADP and Mg2+ supports an associative mechanism for phosphoryl transfer., Protein Sci 2006 Jun; 15(6): 1489-93.
• 2006
  Wehenkel A, Fernandez P, Bellinzoni M, Catherinot V, Barilone N, Labesse G, Jackson M, Alzari PM, , The structure of PknB in complex with mitoxantrone, an ATP-competitive inhibitor, suggests a mode of protein kinase regulation in mycobacteria., FEBS Lett 2006 May; 580(13): 3018-22.
• 2005
  Durán R, Villarino A, Bellinzoni M, Wehenkel A, Fernandez P, Boitel B, Cole ST, Alzari PM, Cerveñansky C, , Conserved autophosphorylation pattern in activation loops and juxtamembrane regions of Mycobacterium tuberculosis Ser/Thr protein kinases., Biochem Biophys Res Commun 2005 Aug; 333(3): 858-67.
• 2005
  Bellinzoni M, Buroni S, Pasca MR, Guglierame P, Arcesi F, De Rossi E, Riccardi G, , Glutamine amidotransferase activity of NAD+ synthetase from Mycobacterium tuberculosis depends on an amino-terminal nitrilase domain., Res Microbiol 2005 Mar; 156(2): 173-7.
• 2004
  Pasca MR, Guglierame P, Arcesi F, Bellinzoni M, De Rossi E, Riccardi G, , Rv2686c-Rv2687c-Rv2688c, an ABC fluoroquinolone efflux pump in Mycobacterium tuberculosis., Antimicrob Agents Chemother 2004 Aug; 48(8): 3175-8.
• 2003
  Bellinzoni M, Riccardi G, , Techniques and applications: The heterologous expression of Mycobacterium tuberculosis genes is an uphill road., Trends Microbiol 2003 Aug; 11(8): 351-8.
• 2003
  Terwilliger TC, Park MS, Waldo GS, Berendzen J, Hung LW, Kim CY, Smith CV, Sacchettini JC, Bellinzoni M, Bossi R, De Rossi E, Mattevi A, Milano A, Riccardi G, Rizzi M, Roberts MM, Coker AR, Fossati G, Mascagni P, Coates AR, Wood SP, Goulding CW, Apostol MI, Anderson DH, Gill HS, Eisenberg DS, Taneja B, Mande S, Pohl E, Lamzin V, Tucker P, Wilmanns M, Colovos C, Meyer-Klaucke W, Munro AW, McLean KJ, Marshall KR, Leys D, Yang JK, Yoon HJ, Lee BI, Lee MG, Kwak JE, Han BW, Lee JY, Baek SH, Suh SW, Komen MM, Arcus VL, Baker EN, Lott JS, Jacobs W, Alber T, Rupp B, The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology, Tuberculosis (Edinb) 2003;83(4):223-49.
• 2002
  De Rossi E, Arrigo P, Bellinzoni M, Silva PA, Martín C, Aínsa JA, Guglierame P, Riccardi G, , The multidrug transporters belonging to major facilitator superfamily in Mycobacterium tuberculosis., Mol Med 2002 Nov; 8(11): 714-24.
• 2002
  Almici C, Imberti L, Lanfranchi A, Verardi R, Bellinzoni M, Berta S, Izzi T, , Reconstitution of T-cell receptor repertoire diversity following non-myeloablative allogeneic stem cell transplantation in an acute myeloid leukemia patient., Haematologica 2002 Oct; 87(10): ECR31.
• 2002
  Pirovano S, Bellinzoni M, Matteelli A, Ballerini C, Albertini A, Imberti L, , High prevalence of a variant of SENV in intravenous drug user HIV-infected patients., J Med Virol 2002 Sep; 68(1): 18-23.
• 2002
  Bellinzoni M, De Rossi E, Branzoni M, Milano A, Peverali FA, Rizzi M, Riccardi G, , Heterologous expression, purification, and enzymatic activity of Mycobacterium tuberculosis NAD(+) synthetase., Protein Expr Purif 2002 Aug; 25(3): 547-57.
• 2002
  Pirovano S, Bellinzoni M, Ballerini C, Cariani E, Duse M, Albertini A, Imberti L, , Transmission of SEN virus from mothers to their babies., J Med Virol 2002 Mar; 66(3): 421-7.