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  • team
  • department
  • center
  • program_project
  • nrc
  • whocc
  • project
  • software
  • tool
  • patent
  • Administrative Staff
  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Department Manager
  • Full Professor
  • Graduate Student
  • Lab assistant
  • Non-permanent Researcher
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Operations
  • Head of Structure
  • Honorary President of the Departement
  • Labex Coordinator
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Starting Date
01
Oct 2021
Ending Date
30
Sep 2024
Status
Not started
Members
5
Structures
4
Instituts
1

About

Developing a SHERLOCK platform for multipurpose detection of trypanosomatid Parasites

 

Neglected tropical diseases caused by vector-born trypanosomatids – African trypanosomiases, Chagas disease and leishmaniases – affect both humans and animals, and disproportionately levy an economic burden on those living in poverty. Progression towards their control or elimination is dependent on accurate surveillance using reliable diagnostic tests. SherPa is an original, cutting-edge, multidisciplinary translational project that aims (WP1) to develop highly sensitive and specific SHERLOCK-based detection tools for rapid diagnosis of trypanosomatid infections and drug resistance determination, adapted to both active and passive surveillance, and (WP2) to demonstrate the efficacy of these new tools by conducting epidemiological studies on both human and animal African trypanosomiases in Western Africa in order to investigate the impact of control programs on parasite circulation in endemic regions and determine host reservoir diversity.

 

African trypanosomiases, Chagas disease, leishmaniases, trypanosomatid parasites, SHERLOCK, diagnosis, epidemiological surveillance.

Fundings