Developing a SHERLOCK platform for multipurpose detection of trypanosomatid Parasites Neglected tropical diseases caused by vector-born trypanosomatids – African trypanosomiases, Chagas disease and leishmaniases – affect both humans and animals, and disproportionately levy an […]
SHERLOCK4HAT African trypanosomes are transmitted by the bite of the tsetse fly and cause the debilitating, and often fatal, neglected tropical disease sleeping sickness, or Human African Trypanosomiasis (HAT). Trypanosoma brucei gambiense, the parasites […]
2022SHERLOCK4HAT: A CRISPR-based tool kit for diagnosis of Human African Trypanosomiasis., EBioMedicine 2022 Nov; 85(): 104308.
2022VEX1 Influences mVSG Expression During the Transition to Mammalian Infectivity in Trypanosoma brucei., Front Cell Dev Biol 2022 ; 10(): 851475.
2021DNA double strand break position leads to distinct gene expression changes and regulates VSG switching pathway choice., PLoS Pathog 2021 Nov; 17(11): e1010038.
2021The MRN complex promotes DNA repair by homologous recombination and restrains antigenic variation in African trypanosomes., Nucleic Acids Res 2021 Jan; (): .