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Candida albicans genomic diversity and its underlying mechanisms
Christophe D’Enfert (PI)
Following our introduction of Multi-Locus Sequence Typing (MLST) as the state-of-the-art methodology for molecular epidemiology studies of C. albicans, the Fungal Biology and Pathogenicity Unit at Institut Pasteur is now progressing into population genomics […]
2022Multiple Stochastic Parameters Influence Genome Dynamics in a Heterozygous Diploid Eukaryotic Model., J Fungi (Basel) 2022 Jun; 8(7): .
2022The (Lack of) DNA Double-Strand Break Repair Pathway Choice During V(D)J Recombination, Frontiers in Genetics.
2021Factors that influence bidirectional long-tract homozygosis due to double-strand break repair in Candida albicans., Genetics 2021 Mar; (): .
2020Use of CRISPR-Cas9 To Target Homologous Recombination Limits Transformation-Induced Genomic Changes in Candida albicans., mSphere 2020 09; 5(5): .
2019Identification of Recessive Lethal Alleles in the Diploid Genome of a Candida albicans Laboratory Strain Unveils a Potential Role of Repetitive Sequences in Buffering Their Deleterious Impact, mSphere 2019 02;4(1).