Chlamydia infection and infertility
The asyptomatic infection by Chlamydia leads to severe complications such as infertility and ectopic pregnancy. We will attempt to understand how chlamydia infection induces either functional or organic infertility in female genital tract and […]
Innate immune response to C. trachomatis infection in the female genital tract
Chlamydia trachomatis is the most common bacterial cause of sexually transmitted infection and is particularly prevalent in the young population. C. trachomatis is an obligate intracellular bacterium infecting primarily epithelial cells of the genital […]
Early steps of infection We have observed that chlamydia invasion of a host cell triggers a transient ubiquitination at the entry sites. Deubiquitination follows very rapidly (20 min post infection). We have identified a […]
2022Chlamydia trachomatis development requires both host glycolysis and oxidative phosphorylation but has only minor effects on these pathways., J Biol Chem 2022 Aug; 298(9): 102338.
2016The DUF582 proteins of Chlamydia trachomatis bind to components of the ESCRT machinery, which is dispensable for bacterial growth in vitro., Front Cell Infect Microbiol. 2016 Sept;in press.